J 2021

Prevalence of adiposity-based chronic disease in middle-aged adults from Czech Republic: The Kardiovize study

GONZALEZ-RIVAS, J. P., J. I. MECHANICK, J. P. HERNANDEZ, M. M. INFANTE-GARCIA, Iuliia PAVLOVSKA et. al.

Basic information

Original name

Prevalence of adiposity-based chronic disease in middle-aged adults from Czech Republic: The Kardiovize study

Authors

GONZALEZ-RIVAS, J. P. (guarantor), J. I. MECHANICK, J. P. HERNANDEZ, M. M. INFANTE-GARCIA, Iuliia PAVLOVSKA (804 Ukraine, belonging to the institution), J. R. MEDINA-INOJOSA, Sarka KUNZOVA (203 Czech Republic), R. NIETO-MARTINEZ, Jan BROZ (203 Czech Republic), L. BUSETTO, G. A. M. NETO, F. LOPEZ-JIMENEZ, Jana URBANOVA (203 Czech Republic) and G. B. STOKIN

Edition

OBESITY SCIENCE & PRACTICE, HOBOKEN, WILEY, 2021, 2055-2238

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30202 Endocrinology and metabolism

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

RIV identification code

RIV/00216224:14110/21:00121638

Organization unit

Faculty of Medicine

DOI

UT WoS

000647238400001

Keywords in English

adiposity; cardiovascular disease; epidemiology; obesity; overweight

Tags

Tags

International impact, Reviewed
Změněno: 7/12/2021 13:01, Mgr. Tereza Miškechová

Abstract

V originále

Aims/Hypothesis The need for understanding obesity as a chronic disease, its stigmatization, and the lack of actionability related to it demands a new approach. The adiposity-based chronic disease (ABCD) model is based on adiposity amount, distribution, and function, with a three stage complication-centric rather than a body mass index (BMI)-centric approach. The prevalence rates and associated risk factors are presented. Methods In total, 2159 participants were randomly selected from Czechia. ABCD was established as BMI >= 25 kg/m(2) or high body fat percent, or abdominal obesity and then categorized by their adiposity-based complications: Stage 0: none; Stage 1: mild/moderate; Stage 2: severe. Results ABCD prevalence was 62.8%. Stage 0 was 2.3%; Stage 1 was 31.4%; Stage 2 was 29.1%. Comparing with other classifiers, participants in Stage 2 were more likely to have diabetes, hypertension, and metabolic syndrome than those with overweight, obesity, abdominal obesity, and increased fat mass. ABCD showed the highest sensitivity and specificity to detect participants with peripheral artery disease, increased intima media, and vascular disease. Conclusion/Interpretation The ABCD model provides a more sensitive approach that facilitates the early detection and stratification of participants at risk compared to traditional classifiers.