Changes in Cognition and Hemodynamics 1 Year after Carotid
Endarterectomy for Asymptomatic Stenosis

J 2021

Changes in Cognition and Hemodynamics 1 Year after Carotid Endarterectomy for Asymptomatic Stenosis

KOSTAL, Petr, Tomas MRHALEK, Alena KAJANOVA, Martin BOMBIC, Jiri KUBALE et. al.

Basic information

Original name

Changes in Cognition and Hemodynamics 1 Year after Carotid Endarterectomy for Asymptomatic Stenosis

Authors

KOSTAL, Petr (203 Czech Republic), Tomas MRHALEK (203 Czech Republic), Alena KAJANOVA (203 Czech Republic), Martin BOMBIC (703 Slovakia, belonging to the institution), Jiri KUBALE (203 Czech Republic), Ludek STERBA (203 Czech Republic), Svatopluk OSTRY (203 Czech Republic) and Jiri FIEDLER (203 Czech Republic, guarantor)

Edition

Journal of Neurological Surgery, Part A: Central European Neurosurgery, New York, Thieme Medical Publ Inc, 2021, 2193-6315

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30212 Surgery

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 0.984

RIV identification code

RIV/00216224:14110/21:00121770

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1055/s-0040-1720985

UT WoS

000617763500002

Keywords in English

carotid endarterectomy; carotid stenosis; cognitive dissonance; quantitative magnetic resonance angiography

Abstract

V originále

Objectives The impact of a change in hemodynamics on cognitive skills in patients with asymptomatic carotid stenosis (ACS) after carotid endarterectomy (CEA) remains unclear. The aim of this study was to evaluate the results of CEA for ACS at 1 year by assessing the changes in anterior, middle, and posterior cerebral artery blood flow in tandem with changes in cognitive efficiency. Methods Flow volume in cerebral arteries using quantitative magnetic resonance angiography was measured in a group of 14 males and 5 females before and at 1 year after CEA for ACS. Cognitive efficiency was assessed by Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). The values of flow volume were processed using simple ratio (SR) and were used for covariance analyses with changes in cognitive skills after CEA. Results A significant improvement in cognitive efficiency indexes of immediate memory and visuospatial perception at 1 year after CEA for ACS was observed. Simultaneously, a significant deterioration of speech index was noted. During the analysis of association between flow and cognition, the highest correlation could be seen between the middle cerebral artery (MCA) flow and the visuospatial perception. A change in posterior cerebral artery (PCA) flow was associated with an increase in immediate memory index and anterior cerebral artery (ACA) flow change with the speech index. Conclusion Convergence of data supporting the association between revascularization and cognitive improvement were added in a small, single-center cohort of ACS patients undergoing CEA. No significant differences in cognition were seen between preoperative findings and at 1 year after CEA. Visuospatial perception improvement was linked to flow change in MCA, immediate memory improvement to flow change in PCA, and speech index change to flow change in ACA. Methodical limitations of this small study preclude formulating larger generalizations. Hemodynamic factors in CEA should be assessed in a larger-scale study.

Citovat

KOSTAL, Petr, Tomas MRHALEK, Alena KAJANOVA, Martin BOMBIC, Jiri KUBALE, Ludek STERBA, Svatopluk OSTRY and Jiri FIEDLER. Changes in Cognition and Hemodynamics 1 Year after Carotid Endarterectomy for Asymptomatic Stenosis. Journal of Neurological Surgery, Part A: Central European Neurosurgery. New York: Thieme Medical Publ Inc, 2021, vol. 82, No 06, p. 505-511. ISSN 2193-6315. Available from: https://dx.doi.org/10.1055/s-0040-1720985.

@article{1776199,
   author = {Kostal, Petr and Mrhalek, Tomas and Kajanova, Alena and Bombic, Martin and Kubale, Jiri and Sterba, Ludek and Ostry, Svatopluk and Fiedler, Jiri},
   article_location = {New York},
   article_number = {06},
   doi = {http://dx.doi.org/10.1055/s-0040-1720985},
   keywords = {carotid endarterectomy; carotid stenosis; cognitive dissonance; quantitative magnetic resonance angiography},
   language = {eng},
   issn = {2193-6315},
   journal = {Journal of Neurological Surgery, Part A: Central European Neurosurgery},
   title = {Changes in Cognition and Hemodynamics 1 Year after Carotid Endarterectomy for Asymptomatic Stenosis},
   url = {https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0040-1720985},
   volume = {82},
   year = {2021}
}

TY  - JOUR
ID  - 1776199
AU  - Kostal, Petr - Mrhalek, Tomas - Kajanova, Alena - Bombic, Martin - Kubale, Jiri - Sterba, Ludek - Ostry, Svatopluk - Fiedler, Jiri
PY  - 2021
TI  - Changes in Cognition and Hemodynamics 1 Year after Carotid Endarterectomy for Asymptomatic Stenosis
JF  - Journal of Neurological Surgery, Part A: Central European Neurosurgery
VL  - 82
IS  - 06
SP  - 505-511
EP  - 505-511
PB  - Thieme Medical Publ Inc
SN  - 21936315
KW  - carotid endarterectomy
KW  - carotid stenosis
KW  - cognitive dissonance
KW  - quantitative magnetic resonance angiography
UR  - https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0040-1720985
N2  - Objectives The impact of a change in hemodynamics on cognitive skills in patients with asymptomatic carotid stenosis (ACS) after carotid endarterectomy (CEA) remains unclear. The aim of this study was to evaluate the results of CEA for ACS at 1 year by assessing the changes in anterior, middle, and posterior cerebral artery blood flow in tandem with changes in cognitive efficiency. Methods Flow volume in cerebral arteries using quantitative magnetic resonance angiography was measured in a group of 14 males and 5 females before and at 1 year after CEA for ACS. Cognitive efficiency was assessed by Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). The values of flow volume were processed using simple ratio (SR) and were used for covariance analyses with changes in cognitive skills after CEA. Results A significant improvement in cognitive efficiency indexes of immediate memory and visuospatial perception at 1 year after CEA for ACS was observed. Simultaneously, a significant deterioration of speech index was noted. During the analysis of association between flow and cognition, the highest correlation could be seen between the middle cerebral artery (MCA) flow and the visuospatial perception. A change in posterior cerebral artery (PCA) flow was associated with an increase in immediate memory index and anterior cerebral artery (ACA) flow change with the speech index. Conclusion Convergence of data supporting the association between revascularization and cognitive improvement were added in a small, single-center cohort of ACS patients undergoing CEA. No significant differences in cognition were seen between preoperative findings and at 1 year after CEA. Visuospatial perception improvement was linked to flow change in MCA, immediate memory improvement to flow change in PCA, and speech index change to flow change in ACA. Methodical limitations of this small study preclude formulating larger generalizations. Hemodynamic factors in CEA should be assessed in a larger-scale study.
ER  -

KOSTAL, Petr, Tomas MRHALEK, Alena KAJANOVA, Martin BOMBIC, Jiri KUBALE, Ludek STERBA, Svatopluk OSTRY and Jiri FIEDLER. Changes in Cognition and Hemodynamics 1 Year after Carotid Endarterectomy for Asymptomatic Stenosis. \textit{Journal of Neurological Surgery, Part A: Central European Neurosurgery}. New York: Thieme Medical Publ Inc, 2021, vol.~82, No~06, p.~505-511. ISSN~2193-6315. Available from: https://dx.doi.org/10.1055/s-0040-1720985.

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