| KANOVSKY, Petr, Raymond ROSALES, Pavel OTRUBA, Martin NEVRLY, Lenka HVIZDOSOVA, Robert OPAVSKY, Michaela KAISEROVA, Pavel HOK, Katerina MENSIKOVA, Petr HLUSTIK and Martin BAREŠ. Contemporary clinical neurophysiology applications in dystonia. Journal of Neural Transmission. WIEN: SPRINGER WIEN, 2021, vol. 128, No 4, p. 509-519. ISSN 0300-9564. Available from: https://dx.doi.org/10.1007/s00702-021-02310-6. |
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@article{1776217,
author = {Kanovsky, Petr and Rosales, Raymond and Otruba, Pavel and Nevrly, Martin and Hvizdosova, Lenka and Opavsky, Robert and Kaiserova, Michaela and Hok, Pavel and Mensikova, Katerina and Hlustik, Petr and Bareš, Martin},
article_location = {WIEN},
article_number = {4},
doi = {http://dx.doi.org/10.1007/s00702-021-02310-6},
keywords = {Dystonia; Neurophysiology; Network disorder; Brain plasticity},
language = {eng},
issn = {0300-9564},
journal = {Journal of Neural Transmission},
title = {Contemporary clinical neurophysiology applications in dystonia},
url = {https://link.springer.com/article/10.1007/s00702-021-02310-6},
volume = {128},
year = {2021}
}
TY - JOUR
ID - 1776217
AU - Kanovsky, Petr - Rosales, Raymond - Otruba, Pavel - Nevrly, Martin - Hvizdosova, Lenka - Opavsky, Robert - Kaiserova, Michaela - Hok, Pavel - Mensikova, Katerina - Hlustik, Petr - Bareš, Martin
PY - 2021
TI - Contemporary clinical neurophysiology applications in dystonia
JF - Journal of Neural Transmission
VL - 128
IS - 4
SP - 509-519
EP - 509-519
PB - SPRINGER WIEN
SN - 03009564
KW - Dystonia
KW - Neurophysiology
KW - Network disorder
KW - Brain plasticity
UR - https://link.springer.com/article/10.1007/s00702-021-02310-6
N2 - The complex phenomenological understanding of dystonia has transcended from the clinics to genetics, imaging and neurophysiology. One way in which electrophysiology will impact into the clinics are cases wherein a dystonic clinical presentation may not be typical or a "forme fruste" of the disorder. Indeed, the physiological imprints of dystonia are present regardless of its clinical manifestation. Underpinnings in the understanding of dystonia span from the peripheral, segmental and suprasegmental levels to the cortex, and various electrophysiological tests have been applied in the course of time to elucidate the origin of dystonia pathophysiology. While loss of inhibition remains to be the key finding in this regard, intricacies and variabilities exist, thus leading to a notion that perhaps dystonia should best be gleaned as network disorder. Interestingly, the complex process has now spanned towards the understanding in terms of networks related to the cerebellar circuitry and the neuroplasticity. What is evolving towards a better and cohesive view will be neurophysiology attributes combined with structural dynamic imaging. Such a sound approach will significantly lead to better therapeutic modalities in the future.
ER -
KANOVSKY, Petr, Raymond ROSALES, Pavel OTRUBA, Martin NEVRLY, Lenka HVIZDOSOVA, Robert OPAVSKY, Michaela KAISEROVA, Pavel HOK, Katerina MENSIKOVA, Petr HLUSTIK and Martin BAREŠ. Contemporary clinical neurophysiology applications in dystonia. \textit{Journal of Neural Transmission}. WIEN: SPRINGER WIEN, 2021, vol.~128, No~4, p.~509-519. ISSN~0300-9564. Available from: https://dx.doi.org/10.1007/s00702-021-02310-6.
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