Trichoderma longibrachiatum and Aspergillus fischeri Infection
as a Cause of Skin Graft Failure in a Patient with Critical
Burns after Liver Transplantation

J 2021

Trichoderma longibrachiatum and Aspergillus fischeri Infection as a Cause of Skin Graft Failure in a Patient with Critical Burns after Liver Transplantation

LIPOVÝ, Břetislav, Filip RAŠKA, Iva KOCMANOVA, Marketa HANSLIANOVA, Martin HLADÍK et. al.

Basic information

Original name

Trichoderma longibrachiatum and Aspergillus fischeri Infection as a Cause of Skin Graft Failure in a Patient with Critical Burns after Liver Transplantation

Authors

LIPOVÝ, Břetislav (203 Czech Republic, belonging to the institution), Filip RAŠKA (203 Czech Republic, belonging to the institution), Iva KOCMANOVA (203 Czech Republic), Marketa HANSLIANOVA (203 Czech Republic), Martin HLADÍK (703 Slovakia, guarantor, belonging to the institution), Jakub HOLOUBEK (203 Czech Republic, belonging to the institution), Matěj BEZDÍČEK (203 Czech Republic, belonging to the institution) and Ctirad MACHÁČEK (203 Czech Republic, belonging to the institution)

Edition

Journal of Fungi, BASEL, MDPI, 2021, 2309-608X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10606 Microbiology

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 5.724

RIV identification code

RIV/00216224:14110/21:00121943

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.3390/jof7060487

UT WoS

000666162500001

Keywords in English

dermal substitute; infection; Trichoderma; Aspergillus; critical burns; liver transplantation; immunosuppression

Abstract

V originále

Infectious complications are responsible for the majority of mortalities and morbidities of patients with critical burns. Although bacteria are the predominant etiological agents in such patients, yeasts and fungi have become relatively common causes of infections over the last decade. Here, we report a case of a young man with critical burns on 88% TBSA (total body surface area) arising as a part of polytrauma. The patient's history of orthotopic liver transplantation associated with the patient's need to use combined immunosuppressant therapy was an additional complication. Due to deep burns in the forearm region, we have (after a suitable wound bed preparation) applied a new bi-layered dermal substitute. The patient, however, developed a combined fungal infection in the region of this dermal substitute caused by Trichoderma longibrachiatum and Aspergillus fischeri (the first case ever reported). The infection caused the loss of the split-thickness skin grafts (STSGs); we had to perform repeated hydrosurgical and mechanical debridement and a systemic antifungal treatment prior to re-application of the STSGs. The subsequent skin transplant was successful.

Citovat

LIPOVÝ, Břetislav, Filip RAŠKA, Iva KOCMANOVA, Marketa HANSLIANOVA, Martin HLADÍK, Jakub HOLOUBEK, Matěj BEZDÍČEK and Ctirad MACHÁČEK. Trichoderma longibrachiatum and Aspergillus fischeri Infection as a Cause of Skin Graft Failure in a Patient with Critical Burns after Liver Transplantation. Journal of Fungi. BASEL: MDPI, 2021, vol. 7, No 6, p. 1-10. ISSN 2309-608X. Available from: https://dx.doi.org/10.3390/jof7060487.

@article{1782960,
   author = {Lipový, Břetislav and Raška, Filip and Kocmanova, Iva and Hanslianova, Marketa and Hladík, Martin and Holoubek, Jakub and Bezdíček, Matěj and Macháček, Ctirad},
   article_location = {BASEL},
   article_number = {6},
   doi = {http://dx.doi.org/10.3390/jof7060487},
   keywords = {dermal substitute; infection; Trichoderma; Aspergillus; critical burns; liver transplantation; immunosuppression},
   language = {eng},
   issn = {2309-608X},
   journal = {Journal of Fungi},
   title = {Trichoderma longibrachiatum and Aspergillus fischeri Infection as a Cause of Skin Graft Failure in a Patient with Critical Burns after Liver Transplantation},
   url = {https://www.mdpi.com/2309-608X/7/6/487},
   volume = {7},
   year = {2021}
}

TY  - JOUR
ID  - 1782960
AU  - Lipový, Břetislav - Raška, Filip - Kocmanova, Iva - Hanslianova, Marketa - Hladík, Martin - Holoubek, Jakub - Bezdíček, Matěj - Macháček, Ctirad
PY  - 2021
TI  - Trichoderma longibrachiatum and Aspergillus fischeri Infection as a Cause of Skin Graft Failure in a Patient with Critical Burns after Liver Transplantation
JF  - Journal of Fungi
VL  - 7
IS  - 6
SP  - 1-10
EP  - 1-10
PB  - MDPI
SN  - 2309608X
KW  - dermal substitute
KW  - infection
KW  - Trichoderma
KW  - Aspergillus
KW  - critical burns
KW  - liver transplantation
KW  - immunosuppression
UR  - https://www.mdpi.com/2309-608X/7/6/487
N2  - Infectious complications are responsible for the majority of mortalities and morbidities of patients with critical burns. Although bacteria are the predominant etiological agents in such patients, yeasts and fungi have become relatively common causes of infections over the last decade. Here, we report a case of a young man with critical burns on 88% TBSA (total body surface area) arising as a part of polytrauma. The patient's history of orthotopic liver transplantation associated with the patient's need to use combined immunosuppressant therapy was an additional complication. Due to deep burns in the forearm region, we have (after a suitable wound bed preparation) applied a new bi-layered dermal substitute. The patient, however, developed a combined fungal infection in the region of this dermal substitute caused by Trichoderma longibrachiatum and Aspergillus fischeri (the first case ever reported). The infection caused the loss of the split-thickness skin grafts (STSGs); we had to perform repeated hydrosurgical and mechanical debridement and a systemic antifungal treatment prior to re-application of the STSGs. The subsequent skin transplant was successful.
ER  -

LIPOVÝ, Břetislav, Filip RAŠKA, Iva KOCMANOVA, Marketa HANSLIANOVA, Martin HLADÍK, Jakub HOLOUBEK, Matěj BEZDÍČEK and Ctirad MACHÁČEK. Trichoderma longibrachiatum and Aspergillus fischeri Infection as a Cause of Skin Graft Failure in a Patient with Critical Burns after Liver Transplantation. \textit{Journal of Fungi}. BASEL: MDPI, 2021, vol.~7, No~6, p.~1-10. ISSN~2309-608X. Available from: https://dx.doi.org/10.3390/jof7060487.

Detailed Information on Publication Record