| JERNFORS, Toni, John DANFORTH, Jenni KESANIEMI, Antom LAVRINIENKO, Eugene TUKALENKO, Jiří FAJKUS, Martina DVOŘÁČKOVÁ, Täppio MAPPES and Phillip C. WATTS. Expansion of rDNA and pericentromere satellite repeats in the genomes of bank voles Myodes glareolus exposed to environmental radionuclides. Ecology and Evolution. 111 River st, Hoboken 07030-5774, NJ USA: John Wiley & Sons, 2021, vol. 11, No 13, p. 8754-8767. ISSN 2045-7758. Available from: https://dx.doi.org/10.1002/ece3.7684. |
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@article{1784128,
author = {Jernfors, Toni and Danforth, John and Kesaniemi, Jenni and Lavrinienko, Antom and Tukalenko, Eugene and Fajkus, Jiří and Dvořáčková, Martina and Mappes, Täppio and Watts, Phillip C.},
article_location = {111 River st, Hoboken 07030-5774, NJ USA},
article_number = {13},
doi = {http://dx.doi.org/10.1002/ece3.7684},
keywords = {anthropogenic disturbance; chernobyl; copy number; ionizing radiation; myodes glareolus; rDNA},
language = {eng},
issn = {2045-7758},
journal = {Ecology and Evolution},
title = {Expansion of rDNA and pericentromere satellite repeats in the genomes of bank voles Myodes glareolus exposed to environmental radionuclides},
url = {https://onlinelibrary.wiley.com/doi/10.1002/ece3.7684},
volume = {11},
year = {2021}
}
TY - JOUR
ID - 1784128
AU - Jernfors, Toni - Danforth, John - Kesaniemi, Jenni - Lavrinienko, Antom - Tukalenko, Eugene - Fajkus, Jiří - Dvořáčková, Martina - Mappes, Täppio - Watts, Phillip C.
PY - 2021
TI - Expansion of rDNA and pericentromere satellite repeats in the genomes of bank voles Myodes glareolus exposed to environmental radionuclides
JF - Ecology and Evolution
VL - 11
IS - 13
SP - 8754-8767
EP - 8754-8767
PB - John Wiley & Sons
SN - 20457758
KW - anthropogenic disturbance
KW - chernobyl
KW - copy number
KW - ionizing radiation
KW - myodes glareolus
KW - rDNA
UR - https://onlinelibrary.wiley.com/doi/10.1002/ece3.7684
N2 - Altered copy number of certain highly repetitive regions of the genome, such as satellite DNA within heterochromatin and ribosomal RNA loci (rDNA), is hypothesized to help safeguard the genome against damage derived from external stressors. We quantified copy number of the 18S rDNA and a pericentromeric satellite DNA (Msat-160) in bank voles (Myodes glareolus) inhabiting the Chernobyl Exclusion Zone (CEZ), an area that is contaminated by radionuclides and where organisms are exposed to elevated levels of ionizing radiation. We found a significant increase in 18S rDNA and Msat-160 content in the genomes of bank voles from contaminated locations within the CEZ compared with animals from uncontaminated locations. Moreover, 18S rDNA and Msat-160 copy number were positively correlated in the genomes of bank voles from uncontaminated, but not in the genomes of animals inhabiting contaminated, areas. These results show the capacity for local-scale geographic variation in genome architecture and are consistent with the genomic safeguard hypothesis. Disruption of cellular processes related to genomic stability appears to be a hallmark effect in bank voles inhabiting areas contaminated by radionuclides.
ER -
JERNFORS, Toni, John DANFORTH, Jenni KESANIEMI, Antom LAVRINIENKO, Eugene TUKALENKO, Jiří FAJKUS, Martina DVOŘÁČKOVÁ, Täppio MAPPES and Phillip C. WATTS. Expansion of rDNA and pericentromere satellite repeats in the genomes of bank voles Myodes glareolus exposed to environmental radionuclides. \textit{Ecology and Evolution}. 111 River st, Hoboken 07030-5774, NJ USA: John Wiley \&{} Sons, 2021, vol.~11, No~13, p.~8754-8767. ISSN~2045-7758. Available from: https://dx.doi.org/10.1002/ece3.7684.
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