Detailed Information on Publication Record
2021
Remodeling of Arctic char (Salvelinus alpinus) lipidome under a stimulated scenario of Arctic warming
WANG, Chao, Yufeng GONG, Fuchang DENG, Enmin DING, Jie TANG et. al.Basic information
Original name
Remodeling of Arctic char (Salvelinus alpinus) lipidome under a stimulated scenario of Arctic warming
Authors
WANG, Chao (156 China), Yufeng GONG (156 China), Fuchang DENG (156 China), Enmin DING (156 China), Jie TANG (156 China), Garry Paul CODLING (826 United Kingdom of Great Britain and Northern Ireland, guarantor, belonging to the institution), Jonathan K. CHALLIS (124 Canada), Derek GREEN (124 Canada), Jing WANG (156 China), Qiliang CHEN (156 China), Yuwei XIE (156 China), Shu SU (156 China), Zilin YANG (156 China), Jason RAINE (124 Canada), Paul D. JONES (124 Canada), Song TANG (156 China) and John Paul GIESY (840 United States of America)
Edition
Global Change Biology, Hoboken, USA, Wiley, 2021, 1354-1013
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
10619 Biodiversity conservation
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 13.211
RIV identification code
RIV/00216224:14310/21:00122228
Organization unit
Faculty of Science
UT WoS
000646003100001
Keywords in English
Arctic warming; chronic temperature shifts; dynamic alterations; glycerolipids; glycerophospholipids; lipidomics; machine learning
Tags
Tags
International impact, Reviewed
Změněno: 1/9/2021 22:37, Mgr. Michaela Hylsová, Ph.D.
Abstract
V originále
Arctic warming associated with global climate change poses a significant threat to populations of wildlife in the Arctic. Since lipids play a vital role in adaptation of organisms to variations in temperature, high-resolution mass-spectrometry-based lipidomics can provide insights into adaptive responses of organisms to a warmer environment in the Arctic and help to illustrate potential novel roles of lipids in the process of thermal adaption. In this study, we studied an ecologically and economically important species-Arctic char (Salvelinus alpinus)-with a detailed multi-tissue analysis of the lipidome in response to chronic shifts in temperature using a validated lipidomics workflow. In addition, dynamic alterations in the hepatic lipidome during the time course of shifts in temperature were also characterized. Our results showed that early life stages of Arctic char were more susceptible to variations in temperature. One-year-old Arctic char responded to chronic increases in temperature with coordinated regulation of lipids, including headgroup-specific remodeling of acyl chains in glycerophospholipids (GP) and extensive alterations in composition of lipids in membranes, such as less lyso-GPs, and more ether-GPs and sphingomyelin. Glycerolipids (e.g., triacylglycerol, TG) also participated in adaptive responses of the lipidome of Arctic char. Eight-week-old Arctic char exhibited rapid adaptive alterations of the hepatic lipidome to stepwise decreases in temperature while showing blunted responses to gradual increases in temperature, implying an inability to adapt rapidly to warmer environments. Three common phosphatidylethanolamines (PEs) (PE 36:6|PE 16:1_20:5, PE 38:7|PE 16:1_22:6, and PE 40:7|PE 18:1_22:6) were finally identified as candidate lipid biomarkers for temperature shifts via machine learning approach. Overall, this work provides additional information to a better understanding of underlying regulatory mechanisms of the lipidome of Arctic organisms in the face of near-future warming.
Links
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