SEHNAL, David, S. BITTRICH, M. DESHPANDE, Radka SVOBODOVÁ, K. BERKA, V. BAZGIER, S. VELANKAR, S.K. BURLEY, Jaroslav KOČA and A.S. ROSE. Mol* Viewer: modern web app for 3D visualization and analysis of large biomolecular structures. Nucleic acids research. Oxford: Oxford University Press, 2021, vol. 49, W1, p. "W431"-"W437", 7 pp. ISSN 0305-1048. Available from: https://dx.doi.org/10.1093/nar/gkab314.
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Basic information
Original name Mol* Viewer: modern web app for 3D visualization and analysis of large biomolecular structures
Authors SEHNAL, David (203 Czech Republic, belonging to the institution), S. BITTRICH, M. DESHPANDE, Radka SVOBODOVÁ (203 Czech Republic, guarantor, belonging to the institution), K. BERKA, V. BAZGIER, S. VELANKAR, S.K. BURLEY, Jaroslav KOČA (203 Czech Republic, belonging to the institution) and A.S. ROSE.
Edition Nucleic acids research, Oxford, Oxford University Press, 2021, 0305-1048.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10608 Biochemistry and molecular biology
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 19.160
RIV identification code RIV/00216224:14740/21:00122430
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.1093/nar/gkab314
UT WoS 000672775800055
Keywords in English MOLECULAR-DYNAMICSDATABASE
Tags CF BioData, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Pavla Foltynová, Ph.D., učo 106624. Changed: 13/10/2021 10:54.
Abstract
Large biomolecular structures are being determined experimentally on a daily basis using established techniques such as crystallography and electron microscopy. In addition, emerging integrative or hybrid methods (I/HM) are producing structural models of huge macromolecular machines and assemblies, sometimes containing 100s of millions of non-hydrogen atoms. The performance requirements for visualization and analysis tools delivering these data are increasing rapidly. Significant progress in developing online, web-native three-dimensional (3D) visualization tools was previously accomplished with the introduction of the LiteMol suite and NGL Viewers. Thereafter, Mol* development was jointly initiated by PDBe and RCSB PDB to combine and build on the strengths of LiteMol (developed by PDBe) and NGL (developed by RCSB PDB). The web-native Mol* Viewer enables 3D visualization and streaming of macromolecular coordinate and experimental data, together with capabilities for displaying structure quality, functional, or biological context annotations. High-performance graphics and data management allows users to simultaneously visualise up to hundreds of (superimposed) protein structures, stream molecular dynamics simulation trajectories, render cell-level models, or display huge I/HM structures. It is the primary 3D structure viewer used by PDBe and RCSB PDB. It can be easily integrated into third-party services. Mol* Viewer is open source and freely available at https://molstar.org/.
Links
EF16_013/0001777, research and development projectName: ELIXIR-CZ: Budování kapacit
LM2018131, research and development projectName: Česká národní infrastruktura pro biologická data (Acronym: ELIXIR-CZ)
Investor: Ministry of Education, Youth and Sports of the CR, Czech National Infrastructure for Biological Data
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