| PANOVSKÝ, Roman, Martina DOUBKOVÁ, Mary Luz MOJICA-PISCIOTTI, Tomáš HOLEČEK, Jan MÁCHAL, Věra FEITOVÁ, Lucia MASÁROVÁ, Lukáš OPATŘIL, Vladimír KINCL and Jana VÍŠKOVÁ. Left ventricular myocardial deformation assessment in asymptomatic patients with recently diagnosed sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis. Orphanet Journal of Rare Diseases. London: BMC, 2021, vol. 16, No 1, p. 1-8. ISSN 1750-1172. Available from: https://dx.doi.org/10.1186/s13023-021-02038-2. |
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@article{1795081,
author = {Panovský, Roman and Doubková, Martina and MojicaandPisciotti, Mary Luz and Holeček, Tomáš and Máchal, Jan and Feitová, Věra and Masárová, Lucia and Opatřil, Lukáš and Kincl, Vladimír and Víšková, Jana},
article_location = {London},
article_number = {1},
doi = {http://dx.doi.org/10.1186/s13023-021-02038-2},
keywords = {Cardiac magnetic resonance; Sarcoidosis; Feature tracking; Strain analysis},
language = {eng},
issn = {1750-1172},
journal = {Orphanet Journal of Rare Diseases},
title = {Left ventricular myocardial deformation assessment in asymptomatic patients with recently diagnosed sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis},
url = {https://ojrd.biomedcentral.com/articles/10.1186/s13023-021-02038-2},
volume = {16},
year = {2021}
}
TY - JOUR
ID - 1795081
AU - Panovský, Roman - Doubková, Martina - Mojica-Pisciotti, Mary Luz - Holeček, Tomáš - Máchal, Jan - Feitová, Věra - Masárová, Lucia - Opatřil, Lukáš - Kincl, Vladimír - Víšková, Jana
PY - 2021
TI - Left ventricular myocardial deformation assessment in asymptomatic patients with recently diagnosed sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis
JF - Orphanet Journal of Rare Diseases
VL - 16
IS - 1
SP - 1-8
EP - 1-8
PB - BMC
SN - 17501172
KW - Cardiac magnetic resonance
KW - Sarcoidosis
KW - Feature tracking
KW - Strain analysis
UR - https://ojrd.biomedcentral.com/articles/10.1186/s13023-021-02038-2
N2 - Background Sarcoidosis is a systemic granulomatous disease affecting different organs including the heart. Myocardial strain analysis could potentially detect the early stages of cardiac dysfunction in sarcoidosis patients. The present study aims to assess the use of cardiac magnetic resonance (CMR) strain analysis using feature tracking (FT) in the detection of early cardiac involvement in asymptomatic patients with sarcoidosis. Methods One hundred and thirteen CMR studies of patients with sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis without pre-existing known cardiovascular disease were included in the study and analysed using FT and compared to 22 age and gender-matched controls. Global longitudinal strain (GLS), global circumferential strain (GCS) and global radial strain (GRS) of the left ventricle (LV) were measured. Results The sarcoidosis patients did not significantly differ from the controls in basic demographic data and had normal global and regional systolic LV function—LV ejection fraction (EF) 66 ± 7% vs 65 ± 5% in the controls (p = NS). No statistically significant differences were found in all strain parameters between patients and controls: GLS (− 13.9 ± 3.1 vs. − 14.2 ± 2.5), GCS (− 23.4 ± 4.0 vs. − 22.2 ± 2.9) and GRS (53.4 ± 13.5 vs. 51.2 ± 13.6%) (p = NS). Conclusion Patients with sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis had normal myocardial deformation measured by CMR-FT derived global strain
ER -
PANOVSKÝ, Roman, Martina DOUBKOVÁ, Mary Luz MOJICA-PISCIOTTI, Tomáš HOLEČEK, Jan MÁCHAL, Věra FEITOVÁ, Lucia MASÁROVÁ, Lukáš OPATŘIL, Vladimír KINCL and Jana VÍŠKOVÁ. Left ventricular myocardial deformation assessment in asymptomatic patients with recently diagnosed sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis. \textit{Orphanet Journal of Rare Diseases}. London: BMC, 2021, vol.~16, No~1, p.~1-8. ISSN~1750-1172. Available from: https://dx.doi.org/10.1186/s13023-021-02038-2.
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