Left ventricular myocardial deformation assessment in
asymptomatic patients with recently diagnosed sarcoidosis of
the respiratory tract and/or extrapulmonary sarcoidosis

J 2021

Left ventricular myocardial deformation assessment in asymptomatic patients with recently diagnosed sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis

PANOVSKÝ, Roman, Martina DOUBKOVÁ, Mary Luz MOJICA-PISCIOTTI, Tomáš HOLEČEK, Jan MÁCHAL et. al.

Basic information

Original name

Left ventricular myocardial deformation assessment in asymptomatic patients with recently diagnosed sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis

Authors

PANOVSKÝ, Roman (203 Czech Republic, belonging to the institution), Martina DOUBKOVÁ (203 Czech Republic, belonging to the institution), Mary Luz MOJICA-PISCIOTTI, Tomáš HOLEČEK (203 Czech Republic, belonging to the institution), Jan MÁCHAL (203 Czech Republic, belonging to the institution), Věra FEITOVÁ (203 Czech Republic), Lucia MASÁROVÁ (703 Slovakia, belonging to the institution), Lukáš OPATŘIL (203 Czech Republic, belonging to the institution), Vladimír KINCL (203 Czech Republic, belonging to the institution) and Jana VÍŠKOVÁ (203 Czech Republic, belonging to the institution)

Edition

Orphanet Journal of Rare Diseases, London, BMC, 2021, 1750-1172

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30101 Human genetics

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.303

RIV identification code

RIV/00216224:14110/21:00122474

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1186/s13023-021-02038-2

UT WoS

000701684200002

Keywords in English

Cardiac magnetic resonance; Sarcoidosis; Feature tracking; Strain analysis

Abstract

V originále

Background Sarcoidosis is a systemic granulomatous disease affecting different organs including the heart. Myocardial strain analysis could potentially detect the early stages of cardiac dysfunction in sarcoidosis patients. The present study aims to assess the use of cardiac magnetic resonance (CMR) strain analysis using feature tracking (FT) in the detection of early cardiac involvement in asymptomatic patients with sarcoidosis. Methods One hundred and thirteen CMR studies of patients with sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis without pre-existing known cardiovascular disease were included in the study and analysed using FT and compared to 22 age and gender-matched controls. Global longitudinal strain (GLS), global circumferential strain (GCS) and global radial strain (GRS) of the left ventricle (LV) were measured. Results The sarcoidosis patients did not significantly differ from the controls in basic demographic data and had normal global and regional systolic LV function—LV ejection fraction (EF) 66 ± 7% vs 65 ± 5% in the controls (p = NS). No statistically significant differences were found in all strain parameters between patients and controls: GLS (− 13.9 ± 3.1 vs. − 14.2 ± 2.5), GCS (− 23.4 ± 4.0 vs. − 22.2 ± 2.9) and GRS (53.4 ± 13.5 vs. 51.2 ± 13.6%) (p = NS). Conclusion Patients with sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis had normal myocardial deformation measured by CMR-FT derived global strain

Links

MUNI/A/1685/2020, interní kód MU

Name: Nové trendy v diagnostice a terapii kardiomyopatií

Investor: Masaryk University

Citovat

PANOVSKÝ, Roman, Martina DOUBKOVÁ, Mary Luz MOJICA-PISCIOTTI, Tomáš HOLEČEK, Jan MÁCHAL, Věra FEITOVÁ, Lucia MASÁROVÁ, Lukáš OPATŘIL, Vladimír KINCL and Jana VÍŠKOVÁ. Left ventricular myocardial deformation assessment in asymptomatic patients with recently diagnosed sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis. Orphanet Journal of Rare Diseases. London: BMC, 2021, vol. 16, No 1, p. 1-8. ISSN 1750-1172. Available from: https://dx.doi.org/10.1186/s13023-021-02038-2.

@article{1795081,
   author = {Panovský, Roman and Doubková, Martina and MojicaandPisciotti, Mary Luz and Holeček, Tomáš and Máchal, Jan and Feitová, Věra and Masárová, Lucia and Opatřil, Lukáš and Kincl, Vladimír and Víšková, Jana},
   article_location = {London},
   article_number = {1},
   doi = {http://dx.doi.org/10.1186/s13023-021-02038-2},
   keywords = {Cardiac magnetic resonance; Sarcoidosis; Feature tracking; Strain analysis},
   language = {eng},
   issn = {1750-1172},
   journal = {Orphanet Journal of Rare Diseases},
   title = {Left ventricular myocardial deformation assessment in asymptomatic patients with recently diagnosed sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis},
   url = {https://ojrd.biomedcentral.com/articles/10.1186/s13023-021-02038-2},
   volume = {16},
   year = {2021}
}

TY  - JOUR
ID  - 1795081
AU  - Panovský, Roman - Doubková, Martina - Mojica-Pisciotti, Mary Luz - Holeček, Tomáš - Máchal, Jan - Feitová, Věra - Masárová, Lucia - Opatřil, Lukáš - Kincl, Vladimír - Víšková, Jana
PY  - 2021
TI  - Left ventricular myocardial deformation assessment in asymptomatic patients with recently diagnosed sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis
JF  - Orphanet Journal of Rare Diseases
VL  - 16
IS  - 1
SP  - 1-8
EP  - 1-8
PB  - BMC
SN  - 17501172
KW  - Cardiac magnetic resonance
KW  - Sarcoidosis
KW  - Feature tracking
KW  - Strain analysis
UR  - https://ojrd.biomedcentral.com/articles/10.1186/s13023-021-02038-2
N2  - Background Sarcoidosis is a systemic granulomatous disease affecting different organs including the heart. Myocardial strain analysis could potentially detect the early stages of cardiac dysfunction in sarcoidosis patients. The present study aims to assess the use of cardiac magnetic resonance (CMR) strain analysis using feature tracking (FT) in the detection of early cardiac involvement in asymptomatic patients with sarcoidosis. Methods One hundred and thirteen CMR studies of patients with sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis without pre-existing known cardiovascular disease were included in the study and analysed using FT and compared to 22 age and gender-matched controls. Global longitudinal strain (GLS), global circumferential strain (GCS) and global radial strain (GRS) of the left ventricle (LV) were measured. Results The sarcoidosis patients did not significantly differ from the controls in basic demographic data and had normal global and regional systolic LV function—LV ejection fraction (EF) 66 ± 7% vs 65 ± 5% in the controls (p = NS). No statistically significant differences were found in all strain parameters between patients and controls: GLS (− 13.9 ± 3.1 vs. − 14.2 ± 2.5), GCS (− 23.4 ± 4.0 vs. − 22.2 ± 2.9) and GRS (53.4 ± 13.5 vs. 51.2 ± 13.6%) (p = NS). Conclusion Patients with sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis had normal myocardial deformation measured by CMR-FT derived global strain
ER  -

PANOVSKÝ, Roman, Martina DOUBKOVÁ, Mary Luz MOJICA-PISCIOTTI, Tomáš HOLEČEK, Jan MÁCHAL, Věra FEITOVÁ, Lucia MASÁROVÁ, Lukáš OPATŘIL, Vladimír KINCL and Jana VÍŠKOVÁ. Left ventricular myocardial deformation assessment in asymptomatic patients with recently diagnosed sarcoidosis of the respiratory tract and/or extrapulmonary sarcoidosis. \textit{Orphanet Journal of Rare Diseases}. London: BMC, 2021, vol.~16, No~1, p.~1-8. ISSN~1750-1172. Available from: https://dx.doi.org/10.1186/s13023-021-02038-2.

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