Cognitive Aftereffects of Acute tDCS Coupled with Cognitive
Training: An fMRI Study in Healthy Seniors.

J 2021

Cognitive Aftereffects of Acute tDCS Coupled with Cognitive Training: An fMRI Study in Healthy Seniors.

ŠIMKO, Patrik, Monika PUPÍKOVÁ, Martin GAJDOŠ and Irena REKTOROVÁ

Basic information

Original name

Cognitive Aftereffects of Acute tDCS Coupled with Cognitive Training: An fMRI Study in Healthy Seniors.

Authors

ŠIMKO, Patrik (703 Slovakia, belonging to the institution), Monika PUPÍKOVÁ (203 Czech Republic, belonging to the institution), Martin GAJDOŠ (203 Czech Republic, belonging to the institution) and Irena REKTOROVÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Neural Plasticity, 2021, 2090-5904

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30103 Neurosciences

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.144

RIV identification code

RIV/00216224:14740/21:00120153

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1155/2021/6664479

UT WoS

000713168700001

Keywords in English

DIRECT-CURRENT STIMULATION; WORKING-MEMORY; PREFRONTAL CORTEX; BRAIN-STIMULATION; IMPAIRMENT; ATTENTION; NETWORK; IMPROVE

Abstract

V originále

Enhancing cognitive functions through noninvasive brain stimulation is of enormous public interest, particularly for the aging population in whom processes such as working memory are known to decline. In a randomized double-blind crossover study, we investigated the acute behavioral and neural aftereffects of bifrontal and frontoparietal transcranial direct current stimulation (tDCS) combined with visual working memory (VWM) training on 25 highly educated older adults. Resting-state functional connectivity (rs-FC) analysis was performed prior to and after each stimulation session with a focus on the frontoparietal control network (FPCN). The bifrontal montage with anode over the left dorsolateral prefrontal cortex enhanced VWM accuracy as compared to the sham stimulation. With the rs-FC within the FPCN, we observed significant stimulationxtime interaction using bifrontal tDCS. We found no cognitive aftereffects of the frontoparietal tDCS compared to sham stimulation. Our study shows that a single bifrontal tDCS combined with cognitive training may enhance VWM performance and rs-FC within the relevant brain network even in highly educated older adults.

Links

NV18-04-00256, research and development project

Name: Efekt transkraniální stimulace tDCS na zrakovou pozornost u pacientů s mírnou kognitivní poruchou - studie kombinující MRI a neinvazivní mozkovou stimulaci

Investor: Ministry of Health of the CR

90129, large research infrastructures

Name: Czech-BioImaging II

Citovat

ŠIMKO, Patrik, Monika PUPÍKOVÁ, Martin GAJDOŠ and Irena REKTOROVÁ. Cognitive Aftereffects of Acute tDCS Coupled with Cognitive Training: An fMRI Study in Healthy Seniors. Neural Plasticity. 2021, vol. 2021, APR, p. 6664479-6664488. ISSN 2090-5904. Available from: https://dx.doi.org/10.1155/2021/6664479.

@article{1799846,
   author = {Šimko, Patrik and Pupíková, Monika and Gajdoš, Martin and Rektorová, Irena},
   article_number = {APR},
   doi = {http://dx.doi.org/10.1155/2021/6664479},
   keywords = {DIRECT-CURRENT STIMULATION; WORKING-MEMORY; PREFRONTAL CORTEX; BRAIN-STIMULATION; IMPAIRMENT; ATTENTION; NETWORK; IMPROVE},
   language = {eng},
   issn = {2090-5904},
   journal = {Neural Plasticity},
   title = {Cognitive Aftereffects of Acute tDCS Coupled with Cognitive Training: An fMRI Study in Healthy Seniors.},
   url = {https://downloads.hindawi.com/journals/np/2021/6664479.pdf},
   volume = {2021},
   year = {2021}
}

TY  - JOUR
ID  - 1799846
AU  - Šimko, Patrik - Pupíková, Monika - Gajdoš, Martin - Rektorová, Irena
PY  - 2021
TI  - Cognitive Aftereffects of Acute tDCS Coupled with Cognitive Training: An fMRI Study in Healthy Seniors.
JF  - Neural Plasticity
VL  - 2021
IS  - APR
SP  - 6664479
EP  - 6664479
SN  - 20905904
KW  - DIRECT-CURRENT STIMULATION
KW  - WORKING-MEMORY
KW  - PREFRONTAL CORTEX
KW  - BRAIN-STIMULATION
KW  - IMPAIRMENT
KW  - ATTENTION
KW  - NETWORK
KW  - IMPROVE
UR  - https://downloads.hindawi.com/journals/np/2021/6664479.pdf
N2  - Enhancing cognitive functions through noninvasive brain stimulation is of enormous public interest, particularly for the aging population in whom processes such as working memory are known to decline. In a randomized double-blind crossover study, we investigated the acute behavioral and neural aftereffects of bifrontal and frontoparietal transcranial direct current stimulation (tDCS) combined with visual working memory (VWM) training on 25 highly educated older adults. Resting-state functional connectivity (rs-FC) analysis was performed prior to and after each stimulation session with a focus on the frontoparietal control network (FPCN). The bifrontal montage with anode over the left dorsolateral prefrontal cortex enhanced VWM accuracy as compared to the sham stimulation. With the rs-FC within the FPCN, we observed significant stimulationxtime interaction using bifrontal tDCS. We found no cognitive aftereffects of the frontoparietal tDCS compared to sham stimulation. Our study shows that a single bifrontal tDCS combined with cognitive training may enhance VWM performance and rs-FC within the relevant brain network even in highly educated older adults.
ER  -

ŠIMKO, Patrik, Monika PUPÍKOVÁ, Martin GAJDOŠ and Irena REKTOROVÁ. Cognitive Aftereffects of Acute tDCS Coupled with Cognitive Training: An fMRI Study in Healthy Seniors. \textit{Neural Plasticity}. 2021, vol.~2021, APR, p.~6664479-6664488. ISSN~2090-5904. Available from: https://dx.doi.org/10.1155/2021/6664479.

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