Modulation of Working Memory and Resting-State fMRI by tDCS of
the Right Frontoparietal Network

J 2021

Modulation of Working Memory and Resting-State fMRI by tDCS of the Right Frontoparietal Network

PUPÍKOVÁ, Monika, Patrik ŠIMKO, Martin GAJDOŠ and Irena REKTOROVÁ

Basic information

Original name

Modulation of Working Memory and Resting-State fMRI by tDCS of the Right Frontoparietal Network

Authors

PUPÍKOVÁ, Monika (203 Czech Republic, belonging to the institution), Patrik ŠIMKO (703 Slovakia, belonging to the institution), Martin GAJDOŠ (203 Czech Republic, belonging to the institution) and Irena REKTOROVÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Neural Plasticity, LONDON, HINDAWI, 2021, 2090-5904

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30210 Clinical neurology

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.144

RIV identification code

RIV/00216224:14740/21:00120156

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1155/2021/5594305

UT WoS

000683157900001

Keywords in English

Working Memory; Resting-State fMRI; tDCS of the Right Frontoparietal Network

Abstract

V originále

Many cognitive functions, including working memory, are processed within large-scale brain networks. We targeted the right frontoparietal network (FPN) with one session of transcranial direct current stimulation (tDCS) in an attempt to modulate the cognitive speed of a visual working memory task (WMT) in 27 young healthy subjects using a double-blind crossover design. We further explored the neural underpinnings of induced changes by performing resting-state fMRI prior to and immediately after each stimulation session with the main focus on the interaction between a task-positive FPN and a task-negative default mode network (DMN). Twenty minutes of 2 mA anodal tDCS was superior to sham stimulation in terms of cognitive speed manipulation of a subtask with processing of objects and tools in unconventional views (i.e., the higher cognitive load subtask of the offline WMT). This result was linked to the magnitude of resting-state functional connectivity decreases between the stimulated FPN seed and DMN seeds. We provide the first evidence for the action reappraisal mechanism of object and tool processing. Modulation of cognitive speed of the task by tDCS was reflected by FPN-DMN cross-talk changes.

Links

MUNI/A/1465/2020, interní kód MU

Name: Vědomí a kognice u mozkových onemocnění

Investor: Masaryk University

NV18-04-00256, research and development project

Name: Efekt transkraniální stimulace tDCS na zrakovou pozornost u pacientů s mírnou kognitivní poruchou - studie kombinující MRI a neinvazivní mozkovou stimulaci

Investor: Ministry of Health of the CR

90129, large research infrastructures

Name: Czech-BioImaging II

Citovat

PUPÍKOVÁ, Monika, Patrik ŠIMKO, Martin GAJDOŠ and Irena REKTOROVÁ. Modulation of Working Memory and Resting-State fMRI by tDCS of the Right Frontoparietal Network. Neural Plasticity. LONDON: HINDAWI, 2021, vol. 2021, July 2021, p. 1-9. ISSN 2090-5904. Available from: https://dx.doi.org/10.1155/2021/5594305.

@article{1799853,
   author = {Pupíková, Monika and Šimko, Patrik and Gajdoš, Martin and Rektorová, Irena},
   article_location = {LONDON},
   article_number = {July 2021},
   doi = {http://dx.doi.org/10.1155/2021/5594305},
   keywords = {Working Memory; Resting-State fMRI; tDCS of the Right Frontoparietal Network},
   language = {eng},
   issn = {2090-5904},
   journal = {Neural Plasticity},
   title = {Modulation of Working Memory and Resting-State fMRI by tDCS of the Right Frontoparietal Network},
   url = {https://www.hindawi.com/journals/np/2021/5594305/},
   volume = {2021},
   year = {2021}
}

TY  - JOUR
ID  - 1799853
AU  - Pupíková, Monika - Šimko, Patrik - Gajdoš, Martin - Rektorová, Irena
PY  - 2021
TI  - Modulation of Working Memory and Resting-State fMRI by tDCS of the Right Frontoparietal Network
JF  - Neural Plasticity
VL  - 2021
IS  - July 2021
SP  - 1-9
EP  - 1-9
PB  - HINDAWI
SN  - 20905904
KW  - Working Memory
KW  - Resting-State fMRI
KW  - tDCS of the Right Frontoparietal Network
UR  - https://www.hindawi.com/journals/np/2021/5594305/
N2  - Many cognitive functions, including working memory, are processed within large-scale brain networks. We targeted the right frontoparietal network (FPN) with one session of transcranial direct current stimulation (tDCS) in an attempt to modulate the cognitive speed of a visual working memory task (WMT) in 27 young healthy subjects using a double-blind crossover design. We further explored the neural underpinnings of induced changes by performing resting-state fMRI prior to and immediately after each stimulation session with the main focus on the interaction between a task-positive FPN and a task-negative default mode network (DMN). Twenty minutes of 2 mA anodal tDCS was superior to sham stimulation in terms of cognitive speed manipulation of a subtask with processing of objects and tools in unconventional views (i.e., the higher cognitive load subtask of the offline WMT). This result was linked to the magnitude of resting-state functional connectivity decreases between the stimulated FPN seed and DMN seeds. We provide the first evidence for the action reappraisal mechanism of object and tool processing. Modulation of cognitive speed of the task by tDCS was reflected by FPN-DMN cross-talk changes.
ER  -

PUPÍKOVÁ, Monika, Patrik ŠIMKO, Martin GAJDOŠ and Irena REKTOROVÁ. Modulation of Working Memory and Resting-State fMRI by tDCS of the Right Frontoparietal Network. \textit{Neural Plasticity}. LONDON: HINDAWI, 2021, vol.~2021, July 2021, p.~1-9. ISSN~2090-5904. Available from: https://dx.doi.org/10.1155/2021/5594305.

Detailed Information on Publication Record