Dynamic Functional Connectivity Signifies the Joint Impact of
Dance Intervention and Cognitive Reserve

J 2021

Dynamic Functional Connectivity Signifies the Joint Impact of Dance Intervention and Cognitive Reserve

MITTEROVÁ, Kristína, Martin LAMOŠ, Radek MAREČEK, Monika PUPÍKOVÁ, Patrik ŠIMKO et. al.

Basic information

Original name

Dynamic Functional Connectivity Signifies the Joint Impact of Dance Intervention and Cognitive Reserve

Authors

MITTEROVÁ, Kristína (703 Slovakia, belonging to the institution), Martin LAMOŠ (203 Czech Republic, belonging to the institution), Radek MAREČEK (203 Czech Republic, belonging to the institution), Monika PUPÍKOVÁ (203 Czech Republic, belonging to the institution), Patrik ŠIMKO (703 Slovakia, belonging to the institution), Roman GRMELA (203 Czech Republic, belonging to the institution), Alena SKOTÁKOVÁ (203 Czech Republic, belonging to the institution), Pavlína VACULÍKOVÁ (203 Czech Republic, belonging to the institution) and Irena REKTOROVÁ (203 Czech Republic, guarantor, belonging to the institution)

Edition

Frontiers in aging neuroscience, 2021, 1663-4365

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30103 Neurosciences

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 5.702

RIV identification code

RIV/00216224:14740/21:00120157

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.3389/fnagi.2021.724094

UT WoS

000756942000001

Keywords in English

cognitive reserve; dance intervention; dynamic resting-state functional connectivity; attention; bottom-up processing; top-down processing; dwell time; coverage

Abstract

V originále

Research on dance interventions (DIs) in the elderly has shown promising benefits to physical and cognitive outcomes. The effect of DIs on resting-state functional connectivity (rs-FC) varies, which is possibly due to individual variability. In this study, we assessed the moderation effects of residual cognitive reserve (CR) on DI-induced changes in dynamic rs-FC and their association on cognitive outcomes. Dynamic rs-FC (rs-dFC) and cognitive functions were evaluated in non-demented elderly subjects before and after a 6-month DI (n = 36) and a control group, referred to as the life-asusual (LAU) group (n = 32). Using linear mixed models and moderation, we examined the interaction effect of DIs and CR on changes in the dwell time and coverage of rs-dFC. Cognitive reserve was calculated as the residual difference between the observed memory performance and the performance predicted by brain state. Partial correlations accounting for CR evaluated the unique association between changes in rs-dFC and cognition in the DI group. In subjects with lower residual CR, we observed DI-induced increases in dwell time [t(58) = -2.14, p = 0.036] and coverage [t(58) = -2.22, p = 0.030] of a rs-dFC state, which was implicated in bottom-up information processing. Increased dwell time was also correlated with a DI-induced improvement in Symbol Search (r = 0.42, p = 0.02). In subjects with higher residual CR, we observed a DI-induced increase in coverage [t(58) = 2.11, p = 0.039] of another rs-dFC state, which was implicated in top-down information processing. The study showed that DIs have a differential and behaviorally relevant effect on dynamic rs-dFC, but these benefits depend on the current CR level.

Links

EF19_073/0016943, research and development project

Name: Interní grantová agentura Masarykovy univerzity

NU21-04-00652, research and development project

Name: Role kognitivní rezervy pro hodnocení nefarmakologické intervence (Acronym: StimCORE)

Investor: Ministry of Health of the CR, Implication of cognitive reserve in non-pharmacological intervention outcomes, Subprogram 1 - standard

90129, large research infrastructures

Name: Czech-BioImaging II

Citovat

MITTEROVÁ, Kristína, Martin LAMOŠ, Radek MAREČEK, Monika PUPÍKOVÁ, Patrik ŠIMKO, Roman GRMELA, Alena SKOTÁKOVÁ, Pavlína VACULÍKOVÁ and Irena REKTOROVÁ. Dynamic Functional Connectivity Signifies the Joint Impact of Dance Intervention and Cognitive Reserve. Frontiers in aging neuroscience. 2021, vol. 13, SEP, p. 724094-724102. ISSN 1663-4365. Available from: https://dx.doi.org/10.3389/fnagi.2021.724094.

@article{1799855,
   author = {Mitterová, Kristína and Lamoš, Martin and Mareček, Radek and Pupíková, Monika and Šimko, Patrik and Grmela, Roman and Skotáková, Alena and Vaculíková, Pavlína and Rektorová, Irena},
   article_number = {SEP},
   doi = {http://dx.doi.org/10.3389/fnagi.2021.724094},
   keywords = {cognitive reserve; dance intervention; dynamic resting-state functional connectivity; attention; bottom-up processing; top-down processing; dwell time; coverage},
   language = {eng},
   issn = {1663-4365},
   journal = {Frontiers in aging neuroscience},
   title = {Dynamic Functional Connectivity Signifies the Joint Impact of Dance Intervention and Cognitive Reserve},
   url = {https://www.frontiersin.org/articles/10.3389/fnagi.2021.724094/full},
   volume = {13},
   year = {2021}
}

TY  - JOUR
ID  - 1799855
AU  - Mitterová, Kristína - Lamoš, Martin - Mareček, Radek - Pupíková, Monika - Šimko, Patrik - Grmela, Roman - Skotáková, Alena - Vaculíková, Pavlína - Rektorová, Irena
PY  - 2021
TI  - Dynamic Functional Connectivity Signifies the Joint Impact of Dance Intervention and Cognitive Reserve
JF  - Frontiers in aging neuroscience
VL  - 13
IS  - SEP
SP  - 724094
EP  - 724094
SN  - 16634365
KW  - cognitive reserve
KW  - dance intervention
KW  - dynamic resting-state functional connectivity
KW  - attention
KW  - bottom-up processing
KW  - top-down processing
KW  - dwell time
KW  - coverage
UR  - https://www.frontiersin.org/articles/10.3389/fnagi.2021.724094/full
N2  - Research on dance interventions (DIs) in the elderly has shown promising benefits to physical and cognitive outcomes. The effect of DIs on resting-state functional connectivity (rs-FC) varies, which is possibly due to individual variability. In this study, we assessed the moderation effects of residual cognitive reserve (CR) on DI-induced changes in dynamic rs-FC and their association on cognitive outcomes. Dynamic rs-FC (rs-dFC) and cognitive functions were evaluated in non-demented elderly subjects before and after a 6-month DI (n = 36) and a control group, referred to as the life-asusual (LAU) group (n = 32). Using linear mixed models and moderation, we examined the interaction effect of DIs and CR on changes in the dwell time and coverage of rs-dFC. Cognitive reserve was calculated as the residual difference between the observed memory performance and the performance predicted by brain state. Partial correlations accounting for CR evaluated the unique association between changes in rs-dFC and cognition in the DI group. In subjects with lower residual CR, we observed DI-induced increases in dwell time [t(58) = -2.14, p = 0.036] and coverage [t(58) = -2.22, p = 0.030] of a rs-dFC state, which was implicated in bottom-up information processing. Increased dwell time was also correlated with a DI-induced improvement in Symbol Search (r = 0.42, p = 0.02). In subjects with higher residual CR, we observed a DI-induced increase in coverage [t(58) = 2.11, p = 0.039] of another rs-dFC state, which was implicated in top-down information processing. The study showed that DIs have a differential and behaviorally relevant effect on dynamic rs-dFC, but these benefits depend on the current CR level.
ER  -

MITTEROVÁ, Kristína, Martin LAMOŠ, Radek MAREČEK, Monika PUPÍKOVÁ, Patrik ŠIMKO, Roman GRMELA, Alena SKOTÁKOVÁ, Pavlína VACULÍKOVÁ and Irena REKTOROVÁ. Dynamic Functional Connectivity Signifies the Joint Impact of Dance Intervention and Cognitive Reserve. \textit{Frontiers in aging neuroscience}. 2021, vol.~13, SEP, p.~724094-724102. ISSN~1663-4365. Available from: https://dx.doi.org/10.3389/fnagi.2021.724094.

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