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@article{1799857,
author = {Hutařová Vařeková, Ivana and Hutař, Jan and Midlik, Adam and Horský, Vladimír and Hladká, Eva and Svobodová, Radka and Berka, Karel},
article_number = {23},
doi = {http://dx.doi.org/10.1093/bioinformatics/btab505},
keywords = {2DProts database; 2D diagram; proteins; database; ontologie;},
language = {eng},
issn = {1367-4803},
journal = {Bioinformatics},
title = {2DProts: database of family-wide protein secondary structure diagrams},
url = {https://academic.oup.com/bioinformatics/article/37/23/4599/6318387},
volume = {37},
year = {2021}
}
TY - JOUR
ID - 1799857
AU - Hutařová Vařeková, Ivana - Hutař, Jan - Midlik, Adam - Horský, Vladimír - Hladká, Eva - Svobodová, Radka - Berka, Karel
PY - 2021
TI - 2DProts: database of family-wide protein secondary structure diagrams
JF - Bioinformatics
VL - 37
IS - 23
SP - 4599-4601
EP - 4599-4601
PB - Oxford University Press
SN - 13674803
KW - 2DProts database
KW - 2D diagram
KW - proteins
KW - database
KW - ontologie;
UR - https://academic.oup.com/bioinformatics/article/37/23/4599/6318387
N2 - Secondary structures provide a deep insight into the protein architecture. They can serve for comparison between individual protein family members. The most straightforward way how to deal with protein secondary structure is its visualization using 2D diagrams. Several software tools for the generation of 2D diagrams were developed. Unfortunately, they create 2D diagrams based on only a single protein. Therefore, 2D diagrams of two proteins from one family markedly differ. For this reason, we developed the 2DProts database, which contains secondary structure 2D diagrams for all domains from the CATH and all proteins from PDB databases. These 2D diagrams are generated based on a whole protein family, and they also consider information about the 3D arrangement of secondary structure elements. Moreover, 2DProts database contains multiple 2D diagrams, which provide an overview of a whole protein family’s secondary structures. 2DProts is updated weekly and is integrated into CATH.
ER -
HUTAŘOVÁ VAŘEKOVÁ, Ivana, Jan HUTAŘ, Adam MIDLIK, Vladimír HORSKÝ, Eva HLADKÁ, Radka SVOBODOVÁ and Karel BERKA. 2DProts: database of family-wide protein secondary structure diagrams. \textit{Bioinformatics}. Oxford University Press, 2021, vol.~37, No~23, p.~4599-4601. ISSN~1367-4803. Available from: https://dx.doi.org/10.1093/bioinformatics/btab505.
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