J 2022

Predictors of Short- and Long-Term Mortality in Ischemic Stroke: A Community-Based Study in Brno, Czech Republic

BRYNDZIAR, Tomáš, Dominika MATYSKOVÁ, Petra ŠEDOVÁ, Silvie BĚLAŠKOVÁ, Miroslav ZVOLSKÝ et. al.

Basic information

Original name

Predictors of Short- and Long-Term Mortality in Ischemic Stroke: A Community-Based Study in Brno, Czech Republic

Authors

BRYNDZIAR, Tomáš (703 Slovakia, belonging to the institution), Dominika MATYSKOVÁ (203 Czech Republic, belonging to the institution), Petra ŠEDOVÁ (203 Czech Republic, guarantor, belonging to the institution), Silvie BĚLAŠKOVÁ (203 Czech Republic, belonging to the institution), Miroslav ZVOLSKÝ (203 Czech Republic), Josef BEDNAŘÍK (203 Czech Republic, belonging to the institution), Robert D. BROWN and Robert MIKULÍK (203 Czech Republic, belonging to the institution)

Edition

Cerebrovascular Diseases, Basel, S. Karger AG, 2022, 1015-9770

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30210 Clinical neurology

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 2.900

RIV identification code

RIV/00216224:14110/22:00125065

Organization unit

Faculty of Medicine

DOI

UT WoS

000721620800001

Keywords in English

Czech Republic; Ischemic stroke; Mortality

Tags

Tags

International impact, Reviewed
Změněno: 10/8/2023 09:49, Mgr. Marie Šípková, DiS.

Abstract

V originále

Background and Objective: Short- and long-term mortality following ischemic stroke (IS) and their predictors have not been defined in the Czech population, and studies on long-term mortality are largely missing for the populations of Central Europe. Methods: Using the National Register of Hospitalized Patients and the Czech National Mortality Registry, we analyzed data on 1-month, 1-year, and 3-year all-cause mortality for patients admitted with IS to any of the 4 hospitals with a certified stroke unit in Brno, Czech Republic, in 2011. We reviewed discharge summaries and recorded potential factors impacting mortality after the index stroke event. Using univariate and multivariable analyses, we identified predictors of mortality at all 3 time points. Results: In our multivariable model, statin use (odds ratio [OR] 0.095, p < 0.0001), age at stroke (OR 1.03, p = 0.0445), and admission National Institutes of Health Stroke Scale (NIHSS) score (OR 1.16, p < 0.0001) predicted 1-month mortality, while statin use (OR 0.43, p = 0.0004), history of cardiac failure (OR 2.17, p = 0.0137), age at stroke (OR 1.07, p < 0.0001), and admission NIHSS score (OR 1.14, p < 0.0001) predicted 1-year mortality. Statin use (OR 0.54, p = 0.0051), history of cardiac failure (OR 2.13, p = 0.0206), age at stroke (OR 1.07, p < 0.0001), and admission NIHSS score (OR 1.11, p < 0.0001) also predicted 3-year mortality. Conclusions: Our study is the first to report data on short- and long-term mortality rates and their predictors in patients hospitalized with IS in the Czech population. Our results indicate that mortality rates and predictors of mortality are consistent with those reported in studies from other populations throughout the world.