BRYNDZIAR, Tomáš, Dominika MATYSKOVÁ, Petra ŠEDOVÁ, Silvie BĚLAŠKOVÁ, Miroslav ZVOLSKÝ, Josef BEDNAŘÍK, Robert D. BROWN and Robert MIKULÍK. Predictors of Short- and Long-Term Mortality in Ischemic Stroke: A Community-Based Study in Brno, Czech Republic. Cerebrovascular Diseases. Basel: S. Karger AG, 2022, vol. 51, No 3, p. 296-303. ISSN 1015-9770. Available from: https://dx.doi.org/10.1159/000519937.
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Basic information
Original name Predictors of Short- and Long-Term Mortality in Ischemic Stroke: A Community-Based Study in Brno, Czech Republic
Authors BRYNDZIAR, Tomáš (703 Slovakia, belonging to the institution), Dominika MATYSKOVÁ (203 Czech Republic, belonging to the institution), Petra ŠEDOVÁ (203 Czech Republic, guarantor, belonging to the institution), Silvie BĚLAŠKOVÁ (203 Czech Republic, belonging to the institution), Miroslav ZVOLSKÝ (203 Czech Republic), Josef BEDNAŘÍK (203 Czech Republic, belonging to the institution), Robert D. BROWN and Robert MIKULÍK (203 Czech Republic, belonging to the institution).
Edition Cerebrovascular Diseases, Basel, S. Karger AG, 2022, 1015-9770.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30210 Clinical neurology
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 2.900
RIV identification code RIV/00216224:14110/22:00125065
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1159/000519937
UT WoS 000721620800001
Keywords in English Czech Republic; Ischemic stroke; Mortality
Tags 14110127, 14110212, 14110221, 14110313, podil
Tags International impact, Reviewed
Changed by Changed by: Mgr. Marie Šípková, DiS., učo 437722. Changed: 10/8/2023 09:49.
Abstract
Background and Objective: Short- and long-term mortality following ischemic stroke (IS) and their predictors have not been defined in the Czech population, and studies on long-term mortality are largely missing for the populations of Central Europe. Methods: Using the National Register of Hospitalized Patients and the Czech National Mortality Registry, we analyzed data on 1-month, 1-year, and 3-year all-cause mortality for patients admitted with IS to any of the 4 hospitals with a certified stroke unit in Brno, Czech Republic, in 2011. We reviewed discharge summaries and recorded potential factors impacting mortality after the index stroke event. Using univariate and multivariable analyses, we identified predictors of mortality at all 3 time points. Results: In our multivariable model, statin use (odds ratio [OR] 0.095, p < 0.0001), age at stroke (OR 1.03, p = 0.0445), and admission National Institutes of Health Stroke Scale (NIHSS) score (OR 1.16, p < 0.0001) predicted 1-month mortality, while statin use (OR 0.43, p = 0.0004), history of cardiac failure (OR 2.17, p = 0.0137), age at stroke (OR 1.07, p < 0.0001), and admission NIHSS score (OR 1.14, p < 0.0001) predicted 1-year mortality. Statin use (OR 0.54, p = 0.0051), history of cardiac failure (OR 2.13, p = 0.0206), age at stroke (OR 1.07, p < 0.0001), and admission NIHSS score (OR 1.11, p < 0.0001) also predicted 3-year mortality. Conclusions: Our study is the first to report data on short- and long-term mortality rates and their predictors in patients hospitalized with IS in the Czech population. Our results indicate that mortality rates and predictors of mortality are consistent with those reported in studies from other populations throughout the world.
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