ADÁMKOVÁ KRÁKOROVÁ, Dagmar, Jana HALÁMKOVÁ, Štěpán TUČEK, Ondřej BÍLEK, Jan KRISTEK, Tomáš KAZDA, Iva ZAMBO, Regina DEMLOVÁ and Igor KISS. Penis as a primary site of an extraskeletal Ewing sarcoma A case report. Medicine. Philadelphia: Lippincott Williams & Wilkins, 2021, vol. 100, No 11, p. 1-5. ISSN 0025-7974. Available from: https://dx.doi.org/10.1097/MD.0000000000025074.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Penis as a primary site of an extraskeletal Ewing sarcoma A case report
Authors ADÁMKOVÁ KRÁKOROVÁ, Dagmar (203 Czech Republic), Jana HALÁMKOVÁ (203 Czech Republic, guarantor, belonging to the institution), Štěpán TUČEK (203 Czech Republic, belonging to the institution), Ondřej BÍLEK (203 Czech Republic, belonging to the institution), Jan KRISTEK (203 Czech Republic), Tomáš KAZDA (203 Czech Republic, belonging to the institution), Iva ZAMBO (203 Czech Republic, belonging to the institution), Regina DEMLOVÁ (203 Czech Republic, belonging to the institution) and Igor KISS (203 Czech Republic, belonging to the institution).
Edition Medicine, Philadelphia, Lippincott Williams & Wilkins, 2021, 0025-7974.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30218 General and internal medicine
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 1.817
RIV identification code RIV/00216224:14110/21:00120171
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1097/MD.0000000000025074
UT WoS 000659055900064
Keywords (in Czech) extraskeletal Ewing sarcoma; multidisciplinary treatment; penis
Keywords in English extraskeletal Ewing sarcoma; multidisciplinary treatment; penis
Tags 14110112, 14110516, 14110522, 14110811, 14110812, MOÚ, MU, RIV, rivok, user
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 8/2/2022 08:47.
Abstract
Rationale: The Ewing sarcoma family of malignant tumors is a group of tumors characterized by morphologically similar round-cell neoplasms and by the presence of a common chromosomal translocation; Ewing sarcoma family of tumors typically occur in children and young adults between 4 to 15 years of age. The primary tumor usually originates in the bone, extraskeletal localization is rare. Patient concern: We present a case report concerning a 32-year-old male patient with a primary involvement of the penis. Diagnosis: The histopathology from the first penile biopsy showed a small-cell neuroendocrine carcinoma; however, that result was based on a sample obtained at a different facility than the Sarcoma Center, where the investigating pathologist did not have the adequate expertise. The patient then underwent a radical penectomy and a second reading of the histology was demanded after a radical penile amputation when Ewing sarcoma with R1 resection was confirmed. Interventions: The patient was referred to the national Sarcoma Center, where - using a multidisciplinary approach - the treatment was started with curative intent. However, it was preceded by a non-standard initiation of the therapy due to the poor primary diagnosis. Outcomes: The non-standard therapy at the onset of the disease caused a poor prognosis of an otherwise curable diagnosis. Despite all that, the patient survived for a relatively long time. Lessons: The treatment of sarcomas with atypical localizations should be conducted by an experienced multidisciplinary team in a center with experience in sarcoma treatment.
Links
NV18-07-00073, research and development projectName: c-Myb a jeho transkripční program ve fyziologických a patologických osteogenních procesech
Investor: Ministry of Health of the CR
90128, large research infrastructuresName: CZECRIN III
PrintDisplayed: 27/4/2024 05:45