KUSHKEVYCH, Ivan and Josef JAMPÍLEK. Effect of intestinal microbiome, antibiotics, and probiotics in the prevention and management of ulcerative colitis. In Mitesh Kumar Dwivedi; N. Amaresan; A. Sankaranarayanan; E. Helen Kemp. Probiotics in the Prevention and Management of Human Diseases : A Scientific Perspective. Cambridge: Elsevier, 2022, p. 59-92. ISBN 978-0-12-823733-5. Available from: https://dx.doi.org/10.1016/B978-0-12-823733-5.00016-7.
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Basic information
Original name Effect of intestinal microbiome, antibiotics, and probiotics in the prevention and management of ulcerative colitis
Authors KUSHKEVYCH, Ivan (203 Czech Republic, guarantor, belonging to the institution) and Josef JAMPÍLEK.
Edition Cambridge, Probiotics in the Prevention and Management of Human Diseases : A Scientific Perspective, p. 59-92, 34 pp. 2022.
Publisher Elsevier
Other information
Original language English
Type of outcome Chapter(s) of a specialized book
Field of Study 10606 Microbiology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Publication form printed version "print"
WWW URL
RIV identification code RIV/00216224:14310/22:00125081
Organization unit Faculty of Science
ISBN 978-0-12-823733-5
Doi http://dx.doi.org/10.1016/B978-0-12-823733-5.00016-7
Keywords in English Intestinal microbiota; sulfate-reducing bacteria; hydrogen sulfide; bowel diseases; ulcerative colitis; probiotics; prebiotics
Tags rivok, topvydavatel
Tags International impact, Reviewed
Changed by Changed by: Mgr. Marie Šípková, DiS., učo 437722. Changed: 28/3/2023 12:27.
Abstract
More and more people suffer from a variety of chronic inflammatory diseases, which are mainly caused by stress and a deteriorating environment. Chronic inflammatory bowel diseases are one of the most common such diseases. Their treatment is problematic and lengthy, and in fact, patients are never really cured. In addition, these diseases are associated with a number of other intestinal problems. The intestinal microbiome is a great help in the fight against these chronic diseases. This chapter summarizes current literature data on the role of microbiota in the development of human colon diseases. Special attention is paid to the involvement of sulfate- reducing bacteria in the development of ulcerative colitis. They are characterized by methods of molecular hydrogen metabolism by sulfate-reducing bacteria in the intestine. The influence and mechanism of action of the main product of metabolism of these microorganisms—hydrogen sulfide—on cells is described. The properties of antimicrobial drugs used in intestinal diseases are presented, and the importance of probiotics for the prevention and treatment of intestinal diseases is described.
Links
MUNI/A/1425/2020, interní kód MUName: Podpora výzkumné činnosti studentů Mikrobiologie
Investor: Masaryk University
PrintDisplayed: 18/7/2024 03:27