Pilot study of the multicentre DISCHARGE Trial: image quality
and protocol adherence results of computed tomography and
invasive coronary angiography

J 2020

Pilot study of the multicentre DISCHARGE Trial: image quality and protocol adherence results of computed tomography and invasive coronary angiography

RUBEIS, De., G. NAPP, A. E. SCHLATTMANN, P. GELEIJNS, J. LAULE et. al.

Basic information

Original name

Pilot study of the multicentre DISCHARGE Trial: image quality and protocol adherence results of computed tomography and invasive coronary angiography

Authors

RUBEIS, De., G. NAPP, A. E. SCHLATTMANN, P. GELEIJNS, J. LAULE, M. DREGER, H. KOFOED, K. SORGAARD, M. ENGSTROM, T. TILSTED, H. H. BOI, A. PORCU, M. COSSA, S. RODRIGUEZ-PALOMARES, J. F. VALENTE, F. X. ROQUE, A. FEUCHTNER, G. PLANK, F. STECHOVSKY, C. ADLA, T. SCHROEDER, S. ZELESNY, T. GUTBERLET, M.. WOINKE, M. KAROLYI, M. KARADY, J. DONNELLY, P. BALL, P. DODD, J. HENSEY, M. MANCONE, M. CECCACCI, A. BERZINA, M. ZVAIGZNE, L. SAKALYTE, G. BASEVICIUS, A. ILNICKA-SUCKIEL, M. KUSMIERZ, D. FARIA, R. GAMA-RIBEIRO, V. BENEDEK, I. BENEDEK, T. ADJIC, F. CANKOVIC, M. BERRY, C. DELLES, C. THWAITE, E. DAVIS, G. KNUUTI, J. PIETILA, M. KEPKA, C. KRUK, M. VIDAKOVIC, R. NESKOVIC, A. N. LECUMBERRI, I. GONZALES, I. D. RUZSICS, B. FISHER, M. DEWEY and M. FRANCONE

Edition

European Radiology, New York, Springer, 2020, 0938-7994

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30230 Other clinical medicine subjects

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 5.315

DOI

http://dx.doi.org/10.1007/s00330-019-06522-z

UT WoS

000519659200020

Keywords in English

Medical imaging; CT angiography; Angiography; coronary; Coronary artery disease; Trial protocols

Abstract

V originále

Objective To implement detailed EU cardiac computed tomography angiography (CCTA) quality criteria in the multicentre DISCHARGE trial (FP72007-2013, EC-GA 603266), we reviewed image quality and adherence to CCTA protocol and to the recommendations of invasive coronary angiography (ICA) in a pilot study. Materials and methods From every clinical centre, imaging datasets of three patients per arm were assessed for adherence to the inclusion/exclusion criteria of the pilot study, predefined standards for the CCTA protocol and ICA recommendations, image quality and non-diagnostic (NDX) rate. These parameters were compared via multinomial regression and ANOVA. If a site did not reach the minimum quality level, additional datasets had to be sent before entering into the final accepted database (FADB). Results We analysed 226 cases (150 CCTA/76 ICA). The inclusion/exclusion criteria were not met by 6 of the 226 (2.7%) datasets. The predefined standard was not met by 13 of 76 ICA datasets (17.1%). This percentage decreased between the initial CCTA database and the FADB (multinomial regression, 53 of 70 vs 17 of 75 [76%] vs [23%]). The signal-to-noise ratio and contrast-to-noise ratio of the FADB did not improve significantly (ANOVA, p = 0.20; p = 0.09). The CTA NDX rate was reduced, but not significantly (initial CCTA database 15 of 70 [21.4%]) and FADB 9 of 75 [12%]; p = 0.13). Conclusion We were able to increase conformity to the inclusion/exclusion criteria and CCTA protocol, improve image quality and decrease the CCTA NDX rate by implementing EU CCTA quality criteria and ICA recommendations.

Links

90128, large research infrastructures

Name: CZECRIN III

Citovat

@article{1808018,
   author = {Rubeis, De. and Napp, G. and Schlattmann, A. E. and Geleijns, P. and Laule, J. and Dreger, M. and Kofoed, H. and Sorgaard, K. and Engstrom, M. and Tilsted, T. and Boi, H. H. and Porcu, A. and Cossa, M. and RodriguezandPalomares, S. and Valente, J. F. and Roque, F. X. and Feuchtner, A. and Plank, G. and Stechovsky, F. and Adla, C. and Schroeder, T. and Zelesny, S. and Gutberlet, T. and Woinke, M.. and Karolyi, M. and Karady, M. and Donnelly, J. and Ball, P. and Dodd, P. and Hensey, J. and Mancone, M. and Ceccacci, M. and Berzina, A. and Zvaigzne, M. and Sakalyte, L. and Basevicius, G. and IlnickaandSuckiel, A. and Kusmierz, M. and Faria, D. and GamaandRibeiro, R. and Benedek, V. and Benedek, I. and Adjic, T. and Cankovic, F. and Berry, M. and Delles, C. and Thwaite, C. and Davis, E. and Knuuti, G. and Pietila, J. and Kepka, M. and Kruk, C. and Vidakovic, M. and Neskovic, R. and Lecumberri, A. N. and Gonzales, I. and Ruzsics, I. D. and Fisher, B. and Dewey, M. and Francone, M.},
   article_location = {New York},
   article_number = {4},
   doi = {http://dx.doi.org/10.1007/s00330-019-06522-z},
   keywords = {Medical imaging; CT angiography; Angiography; coronary; Coronary artery disease; Trial protocols},
   language = {eng},
   issn = {0938-7994},
   journal = {European Radiology},
   title = {Pilot study of the multicentre DISCHARGE Trial: image quality and protocol adherence results of computed tomography and invasive coronary angiography},
   volume = {30},
   year = {2020}
}

TY  - JOUR
ID  - 1808018
AU  - Rubeis, De. - Napp, G. - Schlattmann, A. E. - Geleijns, P. - Laule, J. - Dreger, M. - Kofoed, H. - Sorgaard, K. - Engstrom, M. - Tilsted, T. - Boi, H. H. - Porcu, A. - Cossa, M. - Rodriguez-Palomares, S. - Valente, J. F. - Roque, F. X. - Feuchtner, A. - Plank, G. - Stechovsky, F. - Adla, C. - Schroeder, T. - Zelesny, S. - Gutberlet, T. - Woinke, M.. - Karolyi, M. - Karady, M. - Donnelly, J. - Ball, P. - Dodd, P. - Hensey, J. - Mancone, M. - Ceccacci, M. - Berzina, A. - Zvaigzne, M. - Sakalyte, L. - Basevicius, G. - Ilnicka-Suckiel, A. - Kusmierz, M. - Faria, D. - Gama-Ribeiro, R. - Benedek, V. - Benedek, I. - Adjic, T. - Cankovic, F. - Berry, M. - Delles, C. - Thwaite, C. - Davis, E. - Knuuti, G. - Pietila, J. - Kepka, M. - Kruk, C. - Vidakovic, M. - Neskovic, R. - Lecumberri, A. N. - Gonzales, I. - Ruzsics, I. D. - Fisher, B. - Dewey, M. - Francone, M.
PY  - 2020
TI  - Pilot study of the multicentre DISCHARGE Trial: image quality and protocol adherence results of computed tomography and invasive coronary angiography
JF  - European Radiology
VL  - 30
IS  - 4
SP  - 1997-2009
EP  - 1997-2009
PB  - Springer
SN  - 09387994
KW  - Medical imaging
KW  - CT angiography
KW  - Angiography
KW  - coronary
KW  - Coronary artery disease
KW  - Trial protocols
N2  - Objective To implement detailed EU cardiac computed tomography angiography (CCTA) quality criteria in the multicentre DISCHARGE trial (FP72007-2013, EC-GA 603266), we reviewed image quality and adherence to CCTA protocol and to the recommendations of invasive coronary angiography (ICA) in a pilot study. Materials and methods From every clinical centre, imaging datasets of three patients per arm were assessed for adherence to the inclusion/exclusion criteria of the pilot study, predefined standards for the CCTA protocol and ICA recommendations, image quality and non-diagnostic (NDX) rate. These parameters were compared via multinomial regression and ANOVA. If a site did not reach the minimum quality level, additional datasets had to be sent before entering into the final accepted database (FADB). Results We analysed 226 cases (150 CCTA/76 ICA). The inclusion/exclusion criteria were not met by 6 of the 226 (2.7%) datasets. The predefined standard was not met by 13 of 76 ICA datasets (17.1%). This percentage decreased between the initial CCTA database and the FADB (multinomial regression, 53 of 70 vs 17 of 75 [76%] vs [23%]). The signal-to-noise ratio and contrast-to-noise ratio of the FADB did not improve significantly (ANOVA, p = 0.20; p = 0.09). The CTA NDX rate was reduced, but not significantly (initial CCTA database 15 of 70 [21.4%]) and FADB 9 of 75 [12%]; p = 0.13). Conclusion We were able to increase conformity to the inclusion/exclusion criteria and CCTA protocol, improve image quality and decrease the CCTA NDX rate by implementing EU CCTA quality criteria and ICA recommendations.
ER  -

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