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@article{1808051, author = {Frelich, M. and Divak, J. and Vodicka, V. and Masarova, M. and Jor, O. and Gal, R.}, article_location = {MELVILLE}, doi = {http://dx.doi.org/10.12659/MSM.911231}, keywords = {Adenoidectomy; Dexamethasone; Postoperative Complications; Postoperative Nausea and Vomiting}, language = {eng}, issn = {1643-3750}, journal = {MEDICAL SCIENCE MONITOR}, note = {RIV/65269705:_____/18:00069466}, title = {Dexamethasone Reduces the Incidence of Postoperative Nausea and Vomiting in Children Undergoing Endoscopic Adenoidectomy under General Anesthesia Without Increasing the Risk of Postoperative Hemorrhage}, url = {https://www.medscimonit.com/abstract/index/idArt/911231}, volume = {24}, year = {2018} }
TY - JOUR ID - 1808051 AU - Frelich, M. - Divak, J. - Vodicka, V. - Masarova, M. - Jor, O. - Gal, R. PY - 2018 TI - Dexamethasone Reduces the Incidence of Postoperative Nausea and Vomiting in Children Undergoing Endoscopic Adenoidectomy under General Anesthesia Without Increasing the Risk of Postoperative Hemorrhage JF - MEDICAL SCIENCE MONITOR VL - 24 SP - 8430-8438 EP - 8430-8438 PB - INT SCIENTIFIC INFORMATION, INC SN - 16433750 N1 - RIV/65269705:_____/18:00069466 KW - Adenoidectomy KW - Dexamethasone KW - Postoperative Complications KW - Postoperative Nausea and Vomiting UR - https://www.medscimonit.com/abstract/index/idArt/911231 N2 - Background: Postoperative nausea and vomiting (PONV) is a common complication of pediatric anesthesia, but the overall incidence of PONV in patients undergoing adenoidectomy is unknown. The aim of this controlled study was to compare the effect of dexamethasone administration with placebo to reduce PONV in children undergoing endoscopic adenoidectomy under general anesthesia. Material/Methods: A randomized placebo-controlled study included 118 pediatric patients who underwent elective endoscopic adenoidectomy under general anesthesia. A dexamethasone-treated (0.15 mg/kg) group (Group D) (n=56) and a placebo group (Group C) (n=62) were randomly assigned. The incidence of nausea and vomiting was recorded on the day of surgery. Postoperative nausea was assessed according to illustrated Baxter Animated Retching Faces (BARF) scale. The Face, Legs, Activity, Cry, and Consolability (FLACC) scale (scores between 0-10) was used to assess pain. Follow-up was performed on the 14th postoperative day by a telephone call. Results: Overall prevalence of postoperative nausea was 25% (30/118) and postoperative vomiting was 14% (17/118). In the first 24 hours following surgery, in Group D, the incidence of nausea and vomiting was 13% and 7%, respectively; in Group C, without pharmacological prophylaxis, the incidence of postoperative nausea and vomiting was 37%, and 21%, respectively. Conclusions: A prospective controlled study in children undergoing endoscopic adenoidectomy under general anesthesia showed that dexamethasone (0.15 mg/kg) significantly reduced the incidence of PONV without increasing the risk of postoperative hemorrhage. Dexamethasone is a safe method for the prevention of PONV that may be recommended in pediatric anesthesiology. ER -
FRELICH, M., J. DIVAK, V. VODICKA, M. MASAROVA, O. JOR and R. GAL. Dexamethasone Reduces the Incidence of Postoperative Nausea and Vomiting in Children Undergoing Endoscopic Adenoidectomy under General Anesthesia Without Increasing the Risk of Postoperative Hemorrhage. \textit{MEDICAL SCIENCE MONITOR}. MELVILLE: INT SCIENTIFIC INFORMATION, INC, 2018, vol.~24, p.~8430-8438. ISSN~1643-3750. Available from: https://dx.doi.org/10.12659/MSM.911231.
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