Autoimmune and limbic encephalitis: case series with some
atypical variables in clinical practice

J 2022

Autoimmune and limbic encephalitis: case series with some atypical variables in clinical practice

ŠTOURAČ, Pavel, Jana BEDNÁŘOVÁ, Pavel ZICHACEK, Zdena CERMAKOVA, Zbysek PAVELEK et. al.

Basic information

Original name

Autoimmune and limbic encephalitis: case series with some atypical variables in clinical practice

Authors

ŠTOURAČ, Pavel (203 Czech Republic, guarantor, belonging to the institution), Jana BEDNÁŘOVÁ (203 Czech Republic, belonging to the institution), Pavel ZICHACEK (203 Czech Republic), Zdena CERMAKOVA (203 Czech Republic), Zbysek PAVELEK (203 Czech Republic) and Martin VALIS (203 Czech Republic)

Edition

NEUROLOGICAL SCIENCES, New York, Springer, 2022, 1590-1874

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30210 Clinical neurology

Country of publisher

Italy

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.300

RIV identification code

RIV/00216224:14110/22:00125087

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1007/s10072-021-05563-x

UT WoS

000687902800001

Keywords in English

Autoimmune and limbic encephalitis; Anti-N-methyl-D-aspartate receptor antibodies

Abstract

V originále

Autoimmune and limbic encephalitides are still rare diseases characterized by rapid diagnostics and treatment development in recent years. The incidence of anti-N-methyl-D- aspartate receptor [NMDAR] encephalitis is about 1.5 per million person per year, and the incidence of paraneoplastic neurological syndromes [PNS] including limbic encephalitis [LE] is about 1.22 per 100 000 person per year (Vogrig et al. J Neurol 267:26-35, 1; Dalmau et al. Ann Neurol 61:25-36, 2). The diagnostic criteria of anti-NMDAR encephalitis are already well established (Zuliani et al. Neurol Sci 40:2017-2030, 10). We provide immunological and clinical characteristics of anti-NMDAR encephalitis case series emphasizing unusual association with colon tumour in one case and complete recovery in two cases. Then we report two cases of onconeural and cell surface antibody negative limbic encephalitis [LE] associated with tumours, seizures, cognitive and behavioural changes resulting in severe cerebellar syndrome and fatal outcome. The clinical characteristics and results of selected paraclinical examinations as electroencephalography [EEG], magnetic resonance imaging [MRI] and cerebrospinal fluid [CSF] analysis are reviewed.

Citovat

ŠTOURAČ, Pavel, Jana BEDNÁŘOVÁ, Pavel ZICHACEK, Zdena CERMAKOVA, Zbysek PAVELEK and Martin VALIS. Autoimmune and limbic encephalitis: case series with some atypical variables in clinical practice. NEUROLOGICAL SCIENCES. New York: Springer, 2022, vol. 43, No 1, p. 687-690. ISSN 1590-1874. Available from: https://dx.doi.org/10.1007/s10072-021-05563-x.

@article{1808665,
   author = {Štourač, Pavel and Bednářová, Jana and Zichacek, Pavel and Cermakova, Zdena and Pavelek, Zbysek and Valis, Martin},
   article_location = {New York},
   article_number = {1},
   doi = {http://dx.doi.org/10.1007/s10072-021-05563-x},
   keywords = {Autoimmune and limbic encephalitis; Anti-N-methyl-D-aspartate receptor antibodies},
   language = {eng},
   issn = {1590-1874},
   journal = {NEUROLOGICAL SCIENCES},
   title = {Autoimmune and limbic encephalitis: case series with some atypical variables in clinical practice},
   url = {https://link.springer.com/article/10.1007%2Fs10072-021-05563-x},
   volume = {43},
   year = {2022}
}

TY  - JOUR
ID  - 1808665
AU  - Štourač, Pavel - Bednářová, Jana - Zichacek, Pavel - Cermakova, Zdena - Pavelek, Zbysek - Valis, Martin
PY  - 2022
TI  - Autoimmune and limbic encephalitis: case series with some atypical variables in clinical practice
JF  - NEUROLOGICAL SCIENCES
VL  - 43
IS  - 1
SP  - 687-690
EP  - 687-690
PB  - Springer
SN  - 15901874
KW  - Autoimmune and limbic encephalitis
KW  - Anti-N-methyl-D-aspartate receptor antibodies
UR  - https://link.springer.com/article/10.1007%2Fs10072-021-05563-x
N2  - Autoimmune and limbic encephalitides are still rare diseases characterized by rapid diagnostics and treatment development in recent years. The incidence of anti-N-methyl-D- aspartate receptor [NMDAR] encephalitis is about 1.5 per million person per year, and the incidence of paraneoplastic neurological syndromes [PNS] including limbic encephalitis [LE] is about 1.22 per 100 000 person per year (Vogrig et al. J Neurol 267:26-35, 1; Dalmau et al. Ann Neurol 61:25-36, 2). The diagnostic criteria of anti-NMDAR encephalitis are already well established (Zuliani et al. Neurol Sci 40:2017-2030, 10). We provide immunological and clinical characteristics of anti-NMDAR encephalitis case series emphasizing unusual association with colon tumour in one case and complete recovery in two cases. Then we report two cases of onconeural and cell surface antibody negative limbic encephalitis [LE] associated with tumours, seizures, cognitive and behavioural changes resulting in severe cerebellar syndrome and fatal outcome. The clinical characteristics and results of selected paraclinical examinations as electroencephalography [EEG], magnetic resonance imaging [MRI] and cerebrospinal fluid [CSF] analysis are reviewed.
ER  -

ŠTOURAČ, Pavel, Jana BEDNÁŘOVÁ, Pavel ZICHACEK, Zdena CERMAKOVA, Zbysek PAVELEK and Martin VALIS. Autoimmune and limbic encephalitis: case series with some atypical variables in clinical practice. \textit{NEUROLOGICAL SCIENCES}. New York: Springer, 2022, vol.~43, No~1, p.~687-690. ISSN~1590-1874. Available from: https://dx.doi.org/10.1007/s10072-021-05563-x.

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