ŠTOURAČ, Pavel, Jan KOLČAVA, Miloš KEŘKOVSKÝ, Tereza KOPŘIVOVÁ, Leoš KŘEN and Josef BEDNAŘÍK. Progressive Tumefactive Demyelination as the Only Result of Extensive Diagnostic Work-Up: A Case Report. Frontiers in Neurology. Lausanne: Frontiers, vol. 12, July 2021, p. 1-4. ISSN 1664-2295. doi:10.3389/fneur.2021.701663. 2021.
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Basic information
Original name Progressive Tumefactive Demyelination as the Only Result of Extensive Diagnostic Work-Up: A Case Report
Authors ŠTOURAČ, Pavel (203 Czech Republic, belonging to the institution), Jan KOLČAVA (203 Czech Republic, guarantor, belonging to the institution), Miloš KEŘKOVSKÝ (203 Czech Republic, belonging to the institution), Tereza KOPŘIVOVÁ (203 Czech Republic, belonging to the institution), Leoš KŘEN (203 Czech Republic, belonging to the institution) and Josef BEDNAŘÍK (203 Czech Republic, belonging to the institution).
Edition Frontiers in Neurology, Lausanne, Frontiers, 2021, 1664-2295.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30210 Clinical neurology
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 4.086
RIV identification code RIV/00216224:14110/21:00123210
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.3389/fneur.2021.701663
UT WoS 000675581600001
Keywords in English demyelinating diseases; multiple sclerosis; neuropathology; neuroradiology; case report
Tags 14110216, 14110221, 14110230, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 10/12/2021 14:34.
Abstract
Tumefactive demyelinating lesions belong to the rare variants of multiple sclerosis, posing a diagnostic challenge since it is difficult to distinguish them from a neoplasm or other brain lesions and they require a careful differential diagnosis. This contribution presents the case report of a young female with progressive tumefactive demyelinating brain and spinal cord lesions. An extensive diagnostic process including two brain biopsies and an autopsy did not reveal any explanatory diagnosis other than multiple sclerosis. The patient was treated by various disease-modifying treatments without significant effect and died from ascendent infection via ventriculoperitoneal shunt resulting in Staphylococcus aureus meningitis.
Links
MUNI/A/1600/2020, interní kód MUName: Diagnostika a patofyziologie neuropatické bolesti (Acronym: PNB)
Investor: Masaryk University
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