| RAŠKA, Jan, Hana KLÍMOVÁ, Kateřina SHEARDOVÁ, Veronika FEDOROVÁ, Hana HŘÍBKOVÁ, Veronika POSPÍŠILOVÁ, Simona VOCHYÁNOVÁ, Tereza VÁŇOVÁ a Dáša BOHAČIAKOVÁ. Generation of three human iPSC lines from patients with a spontaneous late-onset Alzheimer's disease and three sex- and age-matched healthy controls. Stem cell research. Amsterdam: Elsevier, 2021, roč. 53, May 2021, s. 1-5. ISSN 1873-5061. Dostupné z: https://dx.doi.org/10.1016/j.scr.2021.102378. |
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@article{1809519,
author = {Raška, Jan and Klímová, Hana and Sheardová, Kateřina and Fedorová, Veronika and Hříbková, Hana and Pospíšilová, Veronika and Vochyánová, Simona and Váňová, Tereza and Bohačiaková, Dáša},
article_location = {Amsterdam},
article_number = {May 2021},
doi = {http://dx.doi.org/10.1016/j.scr.2021.102378},
keywords = {human iPSC lines; spontaneous late-onset Alzheimer’s disease},
language = {eng},
issn = {1873-5061},
journal = {Stem cell research},
title = {Generation of three human iPSC lines from patients with a spontaneous late-onset Alzheimer's disease and three sex- and age-matched healthy controls},
url = {https://www.sciencedirect.com/science/article/pii/S1873506121002245?via%3Dihub},
volume = {53},
year = {2021}
}
TY - JOUR
ID - 1809519
AU - Raška, Jan - Klímová, Hana - Sheardová, Kateřina - Fedorová, Veronika - Hříbková, Hana - Pospíšilová, Veronika - Vochyánová, Simona - Váňová, Tereza - Bohačiaková, Dáša
PY - 2021
TI - Generation of three human iPSC lines from patients with a spontaneous late-onset Alzheimer's disease and three sex- and age-matched healthy controls
JF - Stem cell research
VL - 53
IS - May 2021
SP - 1-5
EP - 1-5
PB - Elsevier
SN - 18735061
KW - human iPSC lines
KW - spontaneous late-onset Alzheimer’s disease
UR - https://www.sciencedirect.com/science/article/pii/S1873506121002245?via%3Dihub
N2 - Human induced pluripotent stem cell (iPSC) lines were generated from patients with spontaneous late-onset Alzheimer's disease (AD) and three healthy control individuals. Peripheral blood mononuclear cells were reprogrammed with Yamanaka factors (OSKM) using a commercially available Epi5 Reprogramming Kit. The pluripotency of iPSCs was confirmed by the expression of pluripotency factors and by their ability to differentiate to all three germ layers in vitro. Newly derived cell lines can be used to model Alzheimer's disease in vitro.
ER -
RAŠKA, Jan, Hana KLÍMOVÁ, Kateřina SHEARDOVÁ, Veronika FEDOROVÁ, Hana HŘÍBKOVÁ, Veronika POSPÍŠILOVÁ, Simona VOCHYÁNOVÁ, Tereza VÁŇOVÁ a Dáša BOHAČIAKOVÁ. Generation of three human iPSC lines from patients with a spontaneous late-onset Alzheimer's disease and three sex- and age-matched healthy controls. \textit{Stem cell research}. Amsterdam: Elsevier, 2021, roč.~53, May 2021, s.~1-5. ISSN~1873-5061. Dostupné z: https://dx.doi.org/10.1016/j.scr.2021.102378.
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