RAŠKA, Jan, Hana KLÍMOVÁ, Kateřina SHEARDOVÁ, Veronika FEDOROVÁ, Hana HŘÍBKOVÁ, Veronika POSPÍŠILOVÁ, Simona VOCHYÁNOVÁ, Tereza VÁŇOVÁ and Dáša BOHAČIAKOVÁ. Generation of three human iPSC lines from patients with a spontaneous late-onset Alzheimer's disease and three sex- and age-matched healthy controls. Stem cell research. Amsterdam: Elsevier, 2021, vol. 53, May 2021, p. 1-5. ISSN 1873-5061. Available from: https://dx.doi.org/10.1016/j.scr.2021.102378. |
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@article{1809519, author = {Raška, Jan and Klímová, Hana and Sheardová, Kateřina and Fedorová, Veronika and Hříbková, Hana and Pospíšilová, Veronika and Vochyánová, Simona and Váňová, Tereza and Bohačiaková, Dáša}, article_location = {Amsterdam}, article_number = {May 2021}, doi = {http://dx.doi.org/10.1016/j.scr.2021.102378}, keywords = {human iPSC lines; spontaneous late-onset Alzheimer’s disease}, language = {eng}, issn = {1873-5061}, journal = {Stem cell research}, title = {Generation of three human iPSC lines from patients with a spontaneous late-onset Alzheimer's disease and three sex- and age-matched healthy controls}, url = {https://www.sciencedirect.com/science/article/pii/S1873506121002245?via%3Dihub}, volume = {53}, year = {2021} }
TY - JOUR ID - 1809519 AU - Raška, Jan - Klímová, Hana - Sheardová, Kateřina - Fedorová, Veronika - Hříbková, Hana - Pospíšilová, Veronika - Vochyánová, Simona - Váňová, Tereza - Bohačiaková, Dáša PY - 2021 TI - Generation of three human iPSC lines from patients with a spontaneous late-onset Alzheimer's disease and three sex- and age-matched healthy controls JF - Stem cell research VL - 53 IS - May 2021 SP - 1-5 EP - 1-5 PB - Elsevier SN - 18735061 KW - human iPSC lines KW - spontaneous late-onset Alzheimer’s disease UR - https://www.sciencedirect.com/science/article/pii/S1873506121002245?via%3Dihub N2 - Human induced pluripotent stem cell (iPSC) lines were generated from patients with spontaneous late-onset Alzheimer's disease (AD) and three healthy control individuals. Peripheral blood mononuclear cells were reprogrammed with Yamanaka factors (OSKM) using a commercially available Epi5 Reprogramming Kit. The pluripotency of iPSCs was confirmed by the expression of pluripotency factors and by their ability to differentiate to all three germ layers in vitro. Newly derived cell lines can be used to model Alzheimer's disease in vitro. ER -
RAŠKA, Jan, Hana KLÍMOVÁ, Kateřina SHEARDOVÁ, Veronika FEDOROVÁ, Hana HŘÍBKOVÁ, Veronika POSPÍŠILOVÁ, Simona VOCHYÁNOVÁ, Tereza VÁŇOVÁ and Dáša BOHAČIAKOVÁ. Generation of three human iPSC lines from patients with a spontaneous late-onset Alzheimer's disease and three sex- and age-matched healthy controls. \textit{Stem cell research}. Amsterdam: Elsevier, 2021, vol.~53, May 2021, p.~1-5. ISSN~1873-5061. Available from: https://dx.doi.org/10.1016/j.scr.2021.102378.
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