Other formats:
BibTeX
LaTeX
RIS
@article{1809527,
author = {Venclíček, Ondřej and Skřičková, Jana and Brat, Kristián and Fischer, Ondrej and Havel, Libor and Hrnciarik, Michal and Marel, Miloslav and Opalka, Petr and Krakorova, Gabriela and Rozsivalova, Denisa and Kultan, Juraj and Mullerova, Andrea and Zarnayova, Lydia and Smickova, Petra and Vasakova, Martina and Gyorfy, Zsuzsanna and Jirousek, Michal and Krejci, Daniel and Krejci, Jana and Zuna, Petr and Svaton, Martin and Hrda, Kristyna and Duba, Jaroslav and Alahakoon, Jana and Svoboda, Michal and Silar, Jiri},
article_location = {Athens},
article_number = {11},
doi = {http://dx.doi.org/10.21873/anticanres.15368},
keywords = {Lung cancer; non-smokers; clinical registry; NSCLC; survival; driving mutations},
language = {eng},
issn = {0250-7005},
journal = {Anticancer Research},
title = {Lung Cancer in Non-smokers in Czech Republic: Data from LUCAS Lung Cancer Clinical Registry},
url = {https://ar.iiarjournals.org/content/41/11/5549},
volume = {41},
year = {2021}
}
TY - JOUR
ID - 1809527
AU - Venclíček, Ondřej - Skřičková, Jana - Brat, Kristián - Fischer, Ondrej - Havel, Libor - Hrnciarik, Michal - Marel, Miloslav - Opalka, Petr - Krakorova, Gabriela - Rozsivalova, Denisa - Kultan, Juraj - Mullerova, Andrea - Zarnayova, Lydia - Smickova, Petra - Vasakova, Martina - Gyorfy, Zsuzsanna - Jirousek, Michal - Krejci, Daniel - Krejci, Jana - Zuna, Petr - Svaton, Martin - Hrda, Kristyna - Duba, Jaroslav - Alahakoon, Jana - Svoboda, Michal - Silar, Jiri
PY - 2021
TI - Lung Cancer in Non-smokers in Czech Republic: Data from LUCAS Lung Cancer Clinical Registry
JF - Anticancer Research
VL - 41
IS - 11
SP - 5549-5556
EP - 5549-5556
PB - International Institute of Anticancer Research
SN - 02507005
KW - Lung cancer
KW - non-smokers
KW - clinical registry
KW - NSCLC
KW - survival
KW - driving mutations
UR - https://ar.iiarjournals.org/content/41/11/5549
N2 - Background/Aim: LUCAS is a clinical lung cancer registry (ClinicalTrials.gov identifier is NCT04228237), prospectively collecting data from newly diagnosed lung cancer patients in seven pneumooncology centers in the Czech Republic, since June 1, 2018. The aim of the study was to assess the stage of the disease at the time of diagnosis, percentage of morphological types, survival, percentage of driving mutations, eligibility for radical surgery, and percentage of patients who undergo radical surgery, in the non-smoking population in comparison with smokers and former smokers. Patients and Methods: The total number of patients in the registry at the time of the analysis was 2,743. Only 2,439 patients with complete records (smoking status, stage, and type of tumor) were included in this study. Results: The analysis indicated that non-smokers are diagnosed at a later stage of the disease but they have a better survival rate than smokers. Fewer smokers with stage III disease who are eligible for radical surgery will undergo surgery compared to non-smokers with the same clinical stage. Driving mutations are more common in non-smokers, even after adjustment for the more frequent occurrence of adenocarcinoma in the group of non-smokers. Conclusion: The data from LUCAS registry are consistent with already known facts, suggesting that the LUCAS registry is a useful clinical tool.
ER -
VENCLÍČEK, Ondřej, Jana SKŘIČKOVÁ, Kristián BRAT, Ondrej FISCHER, Libor HAVEL, Michal HRNCIARIK, Miloslav MAREL, Petr OPALKA, Gabriela KRAKOROVA, Denisa ROZSIVALOVA, Juraj KULTAN, Andrea MULLEROVA, Lydia ZARNAYOVA, Petra SMICKOVA, Martina VASAKOVA, Zsuzsanna GYORFY, Michal JIROUSEK, Daniel KREJCI, Jana KREJCI, Petr ZUNA, Martin SVATON, Kristyna HRDA, Jaroslav DUBA, Jana ALAHAKOON, Michal SVOBODA and Jiri SILAR. Lung Cancer in Non-smokers in Czech Republic: Data from LUCAS Lung Cancer Clinical Registry. \textit{Anticancer Research}. Athens: International Institute of Anticancer Research, 2021, vol.~41, No~11, p.~5549-5556. ISSN~0250-7005. Available from: https://dx.doi.org/10.21873/anticanres.15368.
|
