Metastatic intracranial spread of adenocarcinoma mimicking
Creutzfeldt-Jakob disease in two cases

J 2021

Metastatic intracranial spread of adenocarcinoma mimicking Creutzfeldt-Jakob disease in two cases

RUSINA, R., Lenka KRAJČOVIČOVÁ, B. SRPOVA and R. MATEJ

Basic information

Original name

Metastatic intracranial spread of adenocarcinoma mimicking Creutzfeldt-Jakob disease in two cases

Authors

RUSINA, R. (203 Czech Republic, guarantor), Lenka KRAJČOVIČOVÁ (703 Slovakia, belonging to the institution), B. SRPOVA (203 Czech Republic) and R. MATEJ (203 Czech Republic)

Edition

Revue neurologique, Paris, Elsevier Masson Editeur, 2021, 0035-3787

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30210 Clinical neurology

Country of publisher

France

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.313

RIV identification code

RIV/00216224:14110/21:00123240

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1016/j.neurol.2020.12.009

UT WoS

000717497200002

Keywords in English

adenocarcinoma; Creutzfeldt-Jakob disease

Abstract

V originále

A 54-year-old female with a known pulmonary adenocarcinoma presented with rapid memory and language disturbances, she was anosognostic and apathetic with a Mini-Mental State Exam score 24/30. MRI showed parieto-occipital cortical ribboning in diffusion-weighted sequences (DWI) (Fig. 1A); cerebrospinal fluid (CSF) analysis found normal proteinorhachia (0,48 g/l), highly increased total tau (1481 ng/ml, N 116–370) and negative protein 14-3-3; testing for paraneoplastic antibodies (anti-Hu, Yo, Ri, CV2, PNMa2/Ta, amphiphysin) and antibodies associated with autoimmune limbic encephalitis (anti-NMDAR, AMPAR, CASPR2, LGI, GABABR) was negative. EEGs were nonspecific. Intravenous methylprednisolone and immunoglobulins were ineffective.

Citovat

RUSINA, R., Lenka KRAJČOVIČOVÁ, B. SRPOVA and R. MATEJ. Metastatic intracranial spread of adenocarcinoma mimicking Creutzfeldt-Jakob disease in two cases. Revue neurologique. Paris: Elsevier Masson Editeur, 2021, vol. 177, No 8, p. 1006-1008. ISSN 0035-3787. Available from: https://dx.doi.org/10.1016/j.neurol.2020.12.009.

@article{1809562,
   author = {Rusina, R. and Krajčovičová, Lenka and Srpova, B. and Matej, R.},
   article_location = {Paris},
   article_number = {8},
   doi = {http://dx.doi.org/10.1016/j.neurol.2020.12.009},
   keywords = {adenocarcinoma; Creutzfeldt-Jakob disease},
   language = {eng},
   issn = {0035-3787},
   journal = {Revue neurologique},
   title = {Metastatic intracranial spread of adenocarcinoma mimicking Creutzfeldt-Jakob disease in two cases},
   url = {https://www.sciencedirect.com/science/article/pii/S0035378721005580?via%3Dihub},
   volume = {177},
   year = {2021}
}

TY  - JOUR
ID  - 1809562
AU  - Rusina, R. - Krajčovičová, Lenka - Srpova, B. - Matej, R.
PY  - 2021
TI  - Metastatic intracranial spread of adenocarcinoma mimicking Creutzfeldt-Jakob disease in two cases
JF  - Revue neurologique
VL  - 177
IS  - 8
SP  - 1006-1008
EP  - 1006-1008
PB  - Elsevier Masson Editeur
SN  - 00353787
KW  - adenocarcinoma
KW  - Creutzfeldt-Jakob disease
UR  - https://www.sciencedirect.com/science/article/pii/S0035378721005580?via%3Dihub
N2  - A 54-year-old female with a known pulmonary adenocarcinoma presented with rapid memory and language disturbances, she was anosognostic and apathetic with a Mini-Mental State Exam score 24/30. MRI showed parieto-occipital cortical ribboning in diffusion-weighted sequences (DWI) (Fig. 1A); cerebrospinal fluid (CSF) analysis found normal proteinorhachia (0,48 g/l), highly increased total tau (1481 ng/ml, N 116–370) and negative protein 14-3-3; testing for paraneoplastic antibodies (anti-Hu, Yo, Ri, CV2, PNMa2/Ta, amphiphysin) and antibodies associated with autoimmune limbic encephalitis (anti-NMDAR, AMPAR, CASPR2, LGI, GABABR) was negative. EEGs were nonspecific. Intravenous methylprednisolone and immunoglobulins were ineffective.
ER  -

RUSINA, R., Lenka KRAJČOVIČOVÁ, B. SRPOVA and R. MATEJ. Metastatic intracranial spread of adenocarcinoma mimicking Creutzfeldt-Jakob disease in two cases. \textit{Revue neurologique}. Paris: Elsevier Masson Editeur, 2021, vol.~177, No~8, p.~1006-1008. ISSN~0035-3787. Available from: https://dx.doi.org/10.1016/j.neurol.2020.12.009.

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