LAMOŠ, Martin, Ivona MORÁVKOVÁ, David ONDRÁČEK, Martina BOČKOVÁ and Irena REKTOROVÁ. Altered Spatiotemporal Dynamics of the Resting Brain in Mild Cognitive Impairment with Lewy Bodies. Movement Disorders. Hoboken: Wiley-Blackwell, 2021, vol. 36, No 10, p. 2435-2440. ISSN 0885-3185. Available from: https://dx.doi.org/10.1002/mds.28741.
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Basic information
Original name Altered Spatiotemporal Dynamics of the Resting Brain in Mild Cognitive Impairment with Lewy Bodies
Authors LAMOŠ, Martin (203 Czech Republic, belonging to the institution), Ivona MORÁVKOVÁ (703 Slovakia, belonging to the institution), David ONDRÁČEK (203 Czech Republic, belonging to the institution), Martina BOČKOVÁ (203 Czech Republic, belonging to the institution) and Irena REKTOROVÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition Movement Disorders, Hoboken, Wiley-Blackwell, 2021, 0885-3185.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30103 Neurosciences
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 9.698
RIV identification code RIV/00216224:14740/21:00120175
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.1002/mds.28741
UT WoS 000680728300001
Keywords in English EEG microstates; synucleinopathy; medication-naive; MCI-LB; prodromal DLB
Tags 14110127, CF MAFIL, podil, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Pavla Foltynová, Ph.D., učo 106624. Changed: 9/2/2022 12:55.
Abstract
Background Electrophysiological markers of prodromal dementia with Lewy bodies were described in the spectral domain. The sub-second temporal resolution may provide additional information. Objective To evaluate electroencephalography (EEG) microstates in patients with mild cognitive impairment with Lewy bodies and to assess the association between their temporal dynamics and the spectral marker. Methods Temporal parameters of microstates were compared between 21 patients with mild cognitive impairment with Lewy bodies and 21 healthy controls. The dominant alpha frequency was correlated with microstate parameters. Results Microstates A-D showed higher occurrence in the patient group. Microstate B additionally revealed shorter mean duration and increased time coverage; its occurrence correlated with the dominant alpha frequency in the patient group. Conclusions Temporal dynamics of all EEG microstates were altered in medication-naive subjects with prodromal dementia with Lewy bodies. Longitudinal follow-up may reveal how EEG microstates reflect progression of brain function deficits and effects of treatment manipulations. (c) 2021 International Parkinson and Movement Disorder Society
Links
LM2018129, research and development projectName: Národní infrastruktura pro biologické a medicínské zobrazování Czech-BioImaging
Investor: Ministry of Education, Youth and Sports of the CR
NU20-04-00294, research and development projectName: Diagnostika onemocnění s Lewyho tělísky v prodromálním stadiu založená na analýze multimodálních dat
Investor: Ministry of Health of the CR, Diagnostics of Lewy body diseases in prodromal stage based on multimodal data analysis
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