Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers
Authors
COHEN-ADAD, Julien, Eva ALONSO-ORTIZ, Mihael ABRAMOVIC, Carina ARNEITZ, Nicole ATCHESON, Laura BARLOW, Robert L BARRY, Markus BARTH, Marco BATTISTON, Christian BÜCHEL, Matthew BUDDE, Virginie CALLOT, Anna J E COMBES, Benjamin De LEENER, Maxime DESCOTEAUX, Paulo Loureiro de SOUSA, Marek DOSTÁL (203 Czech Republic, belonging to the institution), Julien DOYON, Adam DVORAK, Falk EIPPERT, Karla R EPPERSON, Kevin S EPPERSON, Patrick FREUND, Jürgen FINSTERBUSCH, Alexandru FOIAS, Michela FRATINI, Issei FUKUNAGA, Claudia A M Gandini WHEELER-KINGSHOTT, Giancarlo GERMANI, Guillaume GILBERT, Federico GIOVE, Charley GROS, Francesco GRUSSU, Akifumi HAGIWARA, Pierre-Gilles HENRY, Tomáš HORÁK (203 Czech Republic, belonging to the institution), Masaaki HORI, James JOERS, Kouhei KAMIYA, Haleh KARBASFOROUSHAN, Miloš KEŘKOVSKÝ (203 Czech Republic, belonging to the institution), Ali KHATIBI, Joo-Won KIM, Nawal KINANY, Hagen H KITZLER, Shannon KOLIND, Yazhuo KONG, Petr KUDLIČKA (203 Czech Republic, belonging to the institution), Paul KUNTKE, Nyoman D KURNIAWAN, Slawomir KUSMIA, René LABOUNEK, Maria Marcella LAGANÀ, Cornelia LAULE, Christine S LAW, Christophe LENGLET, Tobias LEUTRITZ, Yaou LIU, Sara LLUFRIU, Sean MACKEY, Eloy MARTINEZ-HERAS, Loan MATTERA, Igor NESTRASIL, Kristin P O GRADY, Nico PAPINUTTO, Daniel PAPP, Deborah PARETO, Todd B PARRISH, Anna PICHIECCHIO, Ferran PRADOS, Àlex ROVIRA, Marc J RUITENBERG, Rebecca S SAMSON, Giovanni SAVINI, Maryam SEIF, Alan C SEIFERT, Alex K SMITH, Seth A. SMITH, Zachary A. SMITH, Elisabeth SOLANA, Y. SUZUKI, George TACKLEY, Alexandra TINNERMANN, Jan VALOŠEK, Dimitri Van De VILLE, Marios C. YIANNAKAS, Kenneth A. II. WEBER, Nikolaus WEISKOPF, Richard G. WISE, Patrik O. WYSS and Junqian XU
In a companion paper by Cohen-Adad et al. we introduce the spine generic quantitative MRI protocol that provides valuable metrics for assessing spinal cord macrostructural and microstructural integrity. This protocol was used to acquire a single subject dataset across 19 centers and a multi-subject dataset across 42 centers (for a total of 260 participants), spanning the three main MRI manufacturers: GE, Philips and Siemens. Both datasets are publicly available via git-annex. Data were analysed using the Spinal Cord Toolbox to produce normative values as well as inter/intra-site and inter/intra-manufacturer statistics. Reproducibility for the spine generic protocol was high across sites and manufacturers, with an average inter-site coefficient of variation of less than 5% for all the metrics. Full documentation and results can be found at https://spine-generic.rtfd.io/. The datasets and analysis pipeline will help pave the way towards accessible and reproducible quantitative MRI in the spinal cord.
Links
NV18-04-00159, research and development project
Name: Využití pokročilých magneticko-rezonančních technik k odhalení patofyziologie a zlepšení diagnostiky a praktického managementu degenerativní komprese krční míchy
Investor: Ministry of Health of the CR
681094, interní kód MU
Name: NISCI - Antibodies against Nogo-A to enhance plasticity, regeneration and functional recovery after acute spinal cord injury, a multicenter European randomized double blinded placebo controlled phase II clinical proof of concept trial (Acronym: NISCI)
Investor: European Union, Health, demographic change and wellbeing (Societal Challenges)
COHEN-ADAD, Julien, Eva ALONSO-ORTIZ, Mihael ABRAMOVIC, Carina ARNEITZ, Nicole ATCHESON, Laura BARLOW, Robert L BARRY, Markus BARTH, Marco BATTISTON, Christian BÜCHEL, Matthew BUDDE, Virginie CALLOT, Anna J E COMBES, Benjamin De LEENER, Maxime DESCOTEAUX, Paulo Loureiro de SOUSA, Marek DOSTÁL, Julien DOYON, Adam DVORAK, Falk EIPPERT, Karla R EPPERSON, Kevin S EPPERSON, Patrick FREUND, Jürgen FINSTERBUSCH, Alexandru FOIAS, Michela FRATINI, Issei FUKUNAGA, Claudia A M Gandini WHEELER-KINGSHOTT, Giancarlo GERMANI, Guillaume GILBERT, Federico GIOVE, Charley GROS, Francesco GRUSSU, Akifumi HAGIWARA, Pierre-Gilles HENRY, Tomáš HORÁK, Masaaki HORI, James JOERS, Kouhei KAMIYA, Haleh KARBASFOROUSHAN, Miloš KEŘKOVSKÝ, Ali KHATIBI, Joo-Won KIM, Nawal KINANY, Hagen H KITZLER, Shannon KOLIND, Yazhuo KONG, Petr KUDLIČKA, Paul KUNTKE, Nyoman D KURNIAWAN, Slawomir KUSMIA, René LABOUNEK, Maria Marcella LAGANÀ, Cornelia LAULE, Christine S LAW, Christophe LENGLET, Tobias LEUTRITZ, Yaou LIU, Sara LLUFRIU, Sean MACKEY, Eloy MARTINEZ-HERAS, Loan MATTERA, Igor NESTRASIL, Kristin P O GRADY, Nico PAPINUTTO, Daniel PAPP, Deborah PARETO, Todd B PARRISH, Anna PICHIECCHIO, Ferran PRADOS, Àlex ROVIRA, Marc J RUITENBERG, Rebecca S SAMSON, Giovanni SAVINI, Maryam SEIF, Alan C SEIFERT, Alex K SMITH, Seth A. SMITH, Zachary A. SMITH, Elisabeth SOLANA, Y. SUZUKI, George TACKLEY, Alexandra TINNERMANN, Jan VALOŠEK, Dimitri Van De VILLE, Marios C. YIANNAKAS, Kenneth A. II. WEBER, Nikolaus WEISKOPF, Richard G. WISE, Patrik O. WYSS and Junqian XU. Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers. Scientific Data. Berlin: Nature Research, 2021, vol. 8, No 1, p. 1-17. ISSN 2052-4463. Available from: https://dx.doi.org/10.1038/s41597-021-00941-8.
@article{1812585, author = {CohenandAdad, Julien and AlonsoandOrtiz, Eva and Abramovic, Mihael and Arneitz, Carina and Atcheson, Nicole and Barlow, Laura and Barry, Robert L and Barth, Markus and Battiston, Marco and Büchel, Christian and Budde, Matthew and Callot, Virginie and Combes, Anna J E and Leener, Benjamin De and Descoteaux, Maxime and Sousa, Paulo Loureiro de and Dostál, Marek and Doyon, Julien and Dvorak, Adam and Eippert, Falk and Epperson, Karla R and Epperson, Kevin S and Freund, Patrick and Finsterbusch, Jürgen and Foias, Alexandru and Fratini, Michela and Fukunaga, Issei and WheelerandKingshott, Claudia A M Gandini and Germani, Giancarlo and Gilbert, Guillaume and Giove, Federico and Gros, Charley and Grussu, Francesco and Hagiwara, Akifumi and Henry, PierreandGilles and Horák, Tomáš and Hori, Masaaki and Joers, James and Kamiya, Kouhei and Karbasforoushan, Haleh and Keřkovský, Miloš and Khatibi, Ali and Kim, JooandWon and Kinany, Nawal and Kitzler, Hagen H and Kolind, Shannon and Kong, Yazhuo and Kudlička, Petr and Kuntke, Paul and Kurniawan, Nyoman D and Kusmia, Slawomir and Labounek, René and Laganà, Maria Marcella and Laule, Cornelia and Law, Christine S and Lenglet, Christophe and Leutritz, Tobias and Liu, Yaou and Llufriu, Sara and Mackey, Sean and MartinezandHeras, Eloy and Mattera, Loan and Nestrasil, Igor and Grady, Kristin P O and Papinutto, Nico and Papp, Daniel and Pareto, Deborah and Parrish, Todd B and Pichiecchio, Anna and Prados, Ferran and Rovira, Àlex and Ruitenberg, Marc J and Samson, Rebecca S and Savini, Giovanni and Seif, Maryam and Seifert, Alan C and Smith, Alex K and Smith, Seth A. and Smith, Zachary A. and Solana, Elisabeth and Suzuki, Y. and Tackley, George and Tinnermann, Alexandra and Valošek, Jan and Ville, Dimitri Van De and Yiannakas, Marios C. and Weber, Kenneth A. II. and Weiskopf, Nikolaus and Wise, Richard G. and Wyss, Patrik O. and Xu, Junqian}, article_location = {Berlin}, article_number = {1}, doi = {http://dx.doi.org/10.1038/s41597-021-00941-8}, keywords = {spinal cord; reproducibility; MRI}, language = {eng}, issn = {2052-4463}, journal = {Scientific Data}, title = {Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers}, url = {https://www.nature.com/articles/s41597-021-00941-8}, volume = {8}, year = {2021} }
TY - JOUR ID - 1812585 AU - Cohen-Adad, Julien - Alonso-Ortiz, Eva - Abramovic, Mihael - Arneitz, Carina - Atcheson, Nicole - Barlow, Laura - Barry, Robert L - Barth, Markus - Battiston, Marco - Büchel, Christian - Budde, Matthew - Callot, Virginie - Combes, Anna J E - Leener, Benjamin De - Descoteaux, Maxime - Sousa, Paulo Loureiro de - Dostál, Marek - Doyon, Julien - Dvorak, Adam - Eippert, Falk - Epperson, Karla R - Epperson, Kevin S - Freund, Patrick - Finsterbusch, Jürgen - Foias, Alexandru - Fratini, Michela - Fukunaga, Issei - Wheeler-Kingshott, Claudia A M Gandini - Germani, Giancarlo - Gilbert, Guillaume - Giove, Federico - Gros, Charley - Grussu, Francesco - Hagiwara, Akifumi - Henry, Pierre-Gilles - Horák, Tomáš - Hori, Masaaki - Joers, James - Kamiya, Kouhei - Karbasforoushan, Haleh - Keřkovský, Miloš - Khatibi, Ali - Kim, Joo-Won - Kinany, Nawal - Kitzler, Hagen H - Kolind, Shannon - Kong, Yazhuo - Kudlička, Petr - Kuntke, Paul - Kurniawan, Nyoman D - Kusmia, Slawomir - Labounek, René - Laganà, Maria Marcella - Laule, Cornelia - Law, Christine S - Lenglet, Christophe - Leutritz, Tobias - Liu, Yaou - Llufriu, Sara - Mackey, Sean - Martinez-Heras, Eloy - Mattera, Loan - Nestrasil, Igor - Grady, Kristin P O - Papinutto, Nico - Papp, Daniel - Pareto, Deborah - Parrish, Todd B - Pichiecchio, Anna - Prados, Ferran - Rovira, Àlex - Ruitenberg, Marc J - Samson, Rebecca S - Savini, Giovanni - Seif, Maryam - Seifert, Alan C - Smith, Alex K - Smith, Seth A. - Smith, Zachary A. - Solana, Elisabeth - Suzuki, Y. - Tackley, George - Tinnermann, Alexandra - Valošek, Jan - Ville, Dimitri Van De - Yiannakas, Marios C. - Weber, Kenneth A. II. - Weiskopf, Nikolaus - Wise, Richard G. - Wyss, Patrik O. - Xu, Junqian PY - 2021 TI - Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers JF - Scientific Data VL - 8 IS - 1 SP - 1-17 EP - 1-17 PB - Nature Research SN - 20524463 KW - spinal cord KW - reproducibility KW - MRI UR - https://www.nature.com/articles/s41597-021-00941-8 N2 - In a companion paper by Cohen-Adad et al. we introduce the spine generic quantitative MRI protocol that provides valuable metrics for assessing spinal cord macrostructural and microstructural integrity. This protocol was used to acquire a single subject dataset across 19 centers and a multi-subject dataset across 42 centers (for a total of 260 participants), spanning the three main MRI manufacturers: GE, Philips and Siemens. Both datasets are publicly available via git-annex. Data were analysed using the Spinal Cord Toolbox to produce normative values as well as inter/intra-site and inter/intra-manufacturer statistics. Reproducibility for the spine generic protocol was high across sites and manufacturers, with an average inter-site coefficient of variation of less than 5% for all the metrics. Full documentation and results can be found at https://spine-generic.rtfd.io/. The datasets and analysis pipeline will help pave the way towards accessible and reproducible quantitative MRI in the spinal cord. ER -
COHEN-ADAD, Julien, Eva ALONSO-ORTIZ, Mihael ABRAMOVIC, Carina ARNEITZ, Nicole ATCHESON, Laura BARLOW, Robert L BARRY, Markus BARTH, Marco BATTISTON, Christian BÜCHEL, Matthew BUDDE, Virginie CALLOT, Anna J E COMBES, Benjamin De LEENER, Maxime DESCOTEAUX, Paulo Loureiro de SOUSA, Marek DOSTÁL, Julien DOYON, Adam DVORAK, Falk EIPPERT, Karla R EPPERSON, Kevin S EPPERSON, Patrick FREUND, Jürgen FINSTERBUSCH, Alexandru FOIAS, Michela FRATINI, Issei FUKUNAGA, Claudia A M Gandini WHEELER-KINGSHOTT, Giancarlo GERMANI, Guillaume GILBERT, Federico GIOVE, Charley GROS, Francesco GRUSSU, Akifumi HAGIWARA, Pierre-Gilles HENRY, Tomáš HORÁK, Masaaki HORI, James JOERS, Kouhei KAMIYA, Haleh KARBASFOROUSHAN, Miloš KEŘKOVSKÝ, Ali KHATIBI, Joo-Won KIM, Nawal KINANY, Hagen H KITZLER, Shannon KOLIND, Yazhuo KONG, Petr KUDLIČKA, Paul KUNTKE, Nyoman D KURNIAWAN, Slawomir KUSMIA, René LABOUNEK, Maria Marcella LAGANÀ, Cornelia LAULE, Christine S LAW, Christophe LENGLET, Tobias LEUTRITZ, Yaou LIU, Sara LLUFRIU, Sean MACKEY, Eloy MARTINEZ-HERAS, Loan MATTERA, Igor NESTRASIL, Kristin P O GRADY, Nico PAPINUTTO, Daniel PAPP, Deborah PARETO, Todd B PARRISH, Anna PICHIECCHIO, Ferran PRADOS, Àlex ROVIRA, Marc J RUITENBERG, Rebecca S SAMSON, Giovanni SAVINI, Maryam SEIF, Alan C SEIFERT, Alex K SMITH, Seth A. SMITH, Zachary A. SMITH, Elisabeth SOLANA, Y. SUZUKI, George TACKLEY, Alexandra TINNERMANN, Jan VALOŠEK, Dimitri Van De VILLE, Marios C. YIANNAKAS, Kenneth A. II. WEBER, Nikolaus WEISKOPF, Richard G. WISE, Patrik O. WYSS and Junqian XU. Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers. \textit{Scientific Data}. Berlin: Nature Research, 2021, vol.~8, No~1, p.~1-17. ISSN~2052-4463. Available from: https://dx.doi.org/10.1038/s41597-021-00941-8.