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STRÝČEK, Ondřej, Martin LAMOŠ and Ivan REKTOR. Memory retrieval in temporal lobe epilepsy is related to functional segregation of the mesiotemporal structures. EPILEPSY & BEHAVIOR. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE, 2021, vol. 122, SEP, p. 108196-108199. ISSN 1525-5050. Available from: https://dx.doi.org/10.1016/j.yebeh.2021.108196.
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Basic information
Original name Memory retrieval in temporal lobe epilepsy is related to functional segregation of the mesiotemporal structures
Authors STRÝČEK, Ondřej (203 Czech Republic, belonging to the institution), Martin LAMOŠ (203 Czech Republic, belonging to the institution) and Ivan REKTOR (203 Czech Republic, guarantor, belonging to the institution).
Edition EPILEPSY & BEHAVIOR, SAN DIEGO, ACADEMIC PRESS INC ELSEVIER SCIENCE, 2021, 1525-5050.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30103 Neurosciences
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.337
RIV identification code RIV/00216224:14740/21:00120192
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.1016/j.yebeh.2021.108196
UT WoS 000693182100013
Keywords in English Temporal lobe epilepsy; High-density EEG; Functional connectivity; Memory network
Tags 14110127, podil, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Pavla Foltynová, Ph.D., učo 106624. Changed: 3/1/2022 09:35.
Abstract
Objective: We analyzed the impact of temporal lobe epilepsy (TLE) with hippocampal sclerosis (HS) on functional connectivity (FC) between mesiotemporal structures. Functional connectivity modifications related to word retrieval were investigated. Methods: High-density EEG of 21 patients with TLE with HS (12 left TLE and 9 right TLE) and 10 healthy controls (HCs) were recorded during a verbal subsequent memory paradigm. Electroencephalography data were reconstructed into the source space and FC was calculated from the source activity of regions of interest. Results: A significant decrease in FC between the right-and left-sided mesiotemporal structures in TLE was observed. The decrease was significant only with words that were correctly recognized. The decrease in interhemispheric FC between mesiotemporal structures was found in the 8-to 20-Hz frequency range in both left and right TLE. Significance: The decreased FC between the mesiotemporal structures in TLE is a condition for successful performance of a memory retrieval task. The successful memory retrieval in TLE is related to functional segregation of lesional from nonlesional mesiotemporal structures. This decrease was absent in non successful responses. (c) 2021 Elsevier Inc. All rights reserved.
Links
NU21-04-00254, research and development projectName: Detekce zóny počátku záchvatu u multi-lezionální epilepsie s užitím multimodálního neurozobrazování (Acronym: MultiEPI)
Investor: Ministry of Health of the CR, Detection of seizure onset zone in multi-lesional epilepsies using multimodal imaging methods, Subprogram 1 - standard
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