LIBA, Zuzana, Josef KRAUS, Tomáš NEČAS, Jiri NECAS, Miloslav KLUGAR and Pavel KRSEK. Movement disorders, cerebral palsy and vaccination. European Journal of Paediatric Neurology. OXFORD: ELSEVIER SCI LTD, 2022, vol. 36, January 2022, p. 143-150. ISSN 1090-3798. Available from: https://dx.doi.org/10.1016/j.ejpn.2021.12.006.
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Basic information
Original name Movement disorders, cerebral palsy and vaccination
Authors LIBA, Zuzana (203 Czech Republic), Josef KRAUS (203 Czech Republic), Tomáš NEČAS (203 Czech Republic), Jiri NECAS (203 Czech Republic), Miloslav KLUGAR (203 Czech Republic, belonging to the institution) and Pavel KRSEK (203 Czech Republic, guarantor).
Edition European Journal of Paediatric Neurology, OXFORD, ELSEVIER SCI LTD, 2022, 1090-3798.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30210 Clinical neurology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.100
RIV identification code RIV/00216224:14110/22:00125125
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1016/j.ejpn.2021.12.006
UT WoS 000811339200024
Keywords in English Immunization; Vaccination; Movement disorders; Adverse events; Cerebral palsy
Tags 14119612, 14119613, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 19/7/2022 10:42.
Abstract
This review focused on vaccination in children with movement disorders, including cerebral palsy and the movement disorders triggered by vaccination in children with and without neurological disabilities. The following clinical questions were addressed: 1) Can children with movement disorders be vaccinated? 2) Can vaccination trigger movement disorders in children without neurological disabilities? 3) Can vaccination trigger movement disorders in children with neurological disabilities? and 4) Is there any consensus of care concerning vaccination in children with movement disorders? Following the PRISMA reporting guidelines, 1096 records were identified and 34 relevant papers were included. No evidence that vaccinations are contraindicated for children with movement disorders was noticed. Several reports of neurological adverse events, including movement disorders in children without neurological disabilities after various types of vaccination, were found. The reporting rates were low, the causality was controversial, and patient outcomes were mostly favourable. There was limited (if any) evidence in our search that any vaccination leads to any movement disorder exacerbation. Finally, no generally accepted consensus or standards of care concerning vaccination in patients with movement disorders were found. In summary, we found few precautions for vaccination in this group of patients and concluded that general best practice guidelines for immunization should be followed. In addition, influenza and pneumococcal vaccines are recommended because they can reduce morbidity and mortality in individuals severely affected by movement restrictions.
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