J 2022

Movement disorders, cerebral palsy and vaccination

LIBA, Zuzana, Josef KRAUS, Tomáš NEČAS, Jiri NECAS, Miloslav KLUGAR et. al.

Basic information

Original name

Movement disorders, cerebral palsy and vaccination

Authors

LIBA, Zuzana (203 Czech Republic), Josef KRAUS (203 Czech Republic), Tomáš NEČAS (203 Czech Republic), Jiri NECAS (203 Czech Republic), Miloslav KLUGAR (203 Czech Republic, belonging to the institution) and Pavel KRSEK (203 Czech Republic, guarantor)

Edition

European Journal of Paediatric Neurology, OXFORD, ELSEVIER SCI LTD, 2022, 1090-3798

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30210 Clinical neurology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 3.100

RIV identification code

RIV/00216224:14110/22:00125125

Organization unit

Faculty of Medicine

DOI

UT WoS

000811339200024

Keywords in English

Immunization; Vaccination; Movement disorders; Adverse events; Cerebral palsy

Tags

Tags

International impact, Reviewed
Změněno: 19/7/2022 10:42, Mgr. Tereza Miškechová

Abstract

V originále

This review focused on vaccination in children with movement disorders, including cerebral palsy and the movement disorders triggered by vaccination in children with and without neurological disabilities. The following clinical questions were addressed: 1) Can children with movement disorders be vaccinated? 2) Can vaccination trigger movement disorders in children without neurological disabilities? 3) Can vaccination trigger movement disorders in children with neurological disabilities? and 4) Is there any consensus of care concerning vaccination in children with movement disorders? Following the PRISMA reporting guidelines, 1096 records were identified and 34 relevant papers were included. No evidence that vaccinations are contraindicated for children with movement disorders was noticed. Several reports of neurological adverse events, including movement disorders in children without neurological disabilities after various types of vaccination, were found. The reporting rates were low, the causality was controversial, and patient outcomes were mostly favourable. There was limited (if any) evidence in our search that any vaccination leads to any movement disorder exacerbation. Finally, no generally accepted consensus or standards of care concerning vaccination in patients with movement disorders were found. In summary, we found few precautions for vaccination in this group of patients and concluded that general best practice guidelines for immunization should be followed. In addition, influenza and pneumococcal vaccines are recommended because they can reduce morbidity and mortality in individuals severely affected by movement restrictions.