Arterial Spin Labeling is a Useful MRI Method for Presurgical
Evaluation in MRI-Negative Focal Epilepsy

J 2021

Arterial Spin Labeling is a Useful MRI Method for Presurgical Evaluation in MRI-Negative Focal Epilepsy

KOJAN, Martin, Martin GAJDOŠ, Pavel ŘÍHA, Irena DOLEŽALOVÁ, Zdeněk ŘEHÁK et. al.

Basic information

Original name

Arterial Spin Labeling is a Useful MRI Method for Presurgical Evaluation in MRI-Negative Focal Epilepsy

Authors

KOJAN, Martin (703 Slovakia, belonging to the institution), Martin GAJDOŠ (203 Czech Republic, belonging to the institution), Pavel ŘÍHA (203 Czech Republic, belonging to the institution), Irena DOLEŽALOVÁ (203 Czech Republic, belonging to the institution), Zdeněk ŘEHÁK (203 Czech Republic) and Ivan REKTOR (203 Czech Republic, guarantor, belonging to the institution)

Edition

Brain Topography, Dordrecht, Springer, 2021, 0896-0267

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30210 Clinical neurology

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.275

RIV identification code

RIV/00216224:14740/21:00120199

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1007/s10548-021-00833-5

UT WoS

000635032600001

Keywords in English

PET; MRI; ASL; CBF; Epilepsy surgery

Abstract

V originále

Arterial spin labeling (ASL) is an MRI technique measuring brain perfusion using magnetically labeled blood as a tracer. The clinical utility of ASL for presurgical evaluation in non-lesional epilepsy as compared with the quantitative analysis of interictal [F-18] fluorodeoxyglucose PET (FDG-PET) was studied. In 10 patients (4 female; median age 29 years) who underwent a complete presurgical evaluation followed by surgical resection, the presurgical FDG-PET and ASL scans were compared with the resection masks using asymmetry index (AI) maps. The positive predictive value (PPV) and sensitivity (SEN), were calculated from the number of voxels inside the mask (true positive), and outside the mask (false positive). The comparison of the PPVs showed better PPV in 6 patients using ASL and in 2 patients with PET. SEN was better in 4 patients using ASL and in 5 patients with PET. According to the Wilcoxon signed rank test for PPV (p = 0.74) and for SEN (p = 0.43), these methods have similar predictive power. ASL is a useful method for presurgical evaluation in non-lesional epilepsy. The main benefits of ASL over PET are that it avoids radiation exposure for patients, and it offers lower costs, higher availability, and better time efficiency.

Links

NV17-32292A, research and development project

Name: Detekce léze u nelezionální epilepsie s využitím multimodálního zobrazování

90129, large research infrastructures

Name: Czech-BioImaging II

Citovat

KOJAN, Martin, Martin GAJDOŠ, Pavel ŘÍHA, Irena DOLEŽALOVÁ, Zdeněk ŘEHÁK and Ivan REKTOR. Arterial Spin Labeling is a Useful MRI Method for Presurgical Evaluation in MRI-Negative Focal Epilepsy. Brain Topography. Dordrecht: Springer, 2021, vol. 34, No 4, p. 504-510. ISSN 0896-0267. Available from: https://dx.doi.org/10.1007/s10548-021-00833-5.

@article{1816725,
   author = {Kojan, Martin and Gajdoš, Martin and Říha, Pavel and Doležalová, Irena and Řehák, Zdeněk and Rektor, Ivan},
   article_location = {Dordrecht},
   article_number = {4},
   doi = {http://dx.doi.org/10.1007/s10548-021-00833-5},
   keywords = {PET; MRI; ASL; CBF; Epilepsy surgery},
   language = {eng},
   issn = {0896-0267},
   journal = {Brain Topography},
   title = {Arterial Spin Labeling is a Useful MRI Method for Presurgical Evaluation in MRI-Negative Focal Epilepsy},
   url = {https://link.springer.com/article/10.1007%2Fs10548-021-00833-5},
   volume = {34},
   year = {2021}
}

TY  - JOUR
ID  - 1816725
AU  - Kojan, Martin - Gajdoš, Martin - Říha, Pavel - Doležalová, Irena - Řehák, Zdeněk - Rektor, Ivan
PY  - 2021
TI  - Arterial Spin Labeling is a Useful MRI Method for Presurgical Evaluation in MRI-Negative Focal Epilepsy
JF  - Brain Topography
VL  - 34
IS  - 4
SP  - 504-510
EP  - 504-510
PB  - Springer
SN  - 08960267
KW  - PET
KW  - MRI
KW  - ASL
KW  - CBF
KW  - Epilepsy surgery
UR  - https://link.springer.com/article/10.1007%2Fs10548-021-00833-5
N2  - Arterial spin labeling (ASL) is an MRI technique measuring brain perfusion using magnetically labeled blood as a tracer. The clinical utility of ASL for presurgical evaluation in non-lesional epilepsy as compared with the quantitative analysis of interictal [F-18] fluorodeoxyglucose PET (FDG-PET) was studied. In 10 patients (4 female; median age 29 years) who underwent a complete presurgical evaluation followed by surgical resection, the presurgical FDG-PET and ASL scans were compared with the resection masks using asymmetry index (AI) maps. The positive predictive value (PPV) and sensitivity (SEN), were calculated from the number of voxels inside the mask (true positive), and outside the mask (false positive). The comparison of the PPVs showed better PPV in 6 patients using ASL and in 2 patients with PET. SEN was better in 4 patients using ASL and in 5 patients with PET. According to the Wilcoxon signed rank test for PPV (p = 0.74) and for SEN (p = 0.43), these methods have similar predictive power. ASL is a useful method for presurgical evaluation in non-lesional epilepsy. The main benefits of ASL over PET are that it avoids radiation exposure for patients, and it offers lower costs, higher availability, and better time efficiency.
ER  -

KOJAN, Martin, Martin GAJDOŠ, Pavel ŘÍHA, Irena DOLEŽALOVÁ, Zdeněk ŘEHÁK and Ivan REKTOR. Arterial Spin Labeling is a Useful MRI Method for Presurgical Evaluation in MRI-Negative Focal Epilepsy. \textit{Brain Topography}. Dordrecht: Springer, 2021, vol.~34, No~4, p.~504-510. ISSN~0896-0267. Available from: https://dx.doi.org/10.1007/s10548-021-00833-5.

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