Thalamic oscillatory activity may predict response to deep
brain stimulation of the anterior nuclei of the thalamus

J 2021

Thalamic oscillatory activity may predict response to deep brain stimulation of the anterior nuclei of the thalamus

DEUTSCHOVÁ, Barbora, P. KLIMES, Z. JORDAN, P. JURAK, L. EROSS et. al.

Basic information

Original name

Thalamic oscillatory activity may predict response to deep brain stimulation of the anterior nuclei of the thalamus

Authors

DEUTSCHOVÁ, Barbora (203 Czech Republic, belonging to the institution), P. KLIMES, Z. JORDAN, P. JURAK, L. EROSS, Martin LAMOŠ (203 Czech Republic, belonging to the institution), J. HALAMEK, Pavel DANIEL (203 Czech Republic, belonging to the institution), Ivan REKTOR (203 Czech Republic, guarantor, belonging to the institution) and D. FABO

Edition

Epilepsia, Hoboken, Wiley-Blackwell, 2021, 0013-9580

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30210 Clinical neurology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 6.740

RIV identification code

RIV/00216224:14740/21:00119502

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1111/epi.16883

UT WoS

000631593800001

Keywords in English

anterior thalamic nucleus; deep brain stimulation; oscillations; prediction

Abstract

V originále

We hypothesized that local/regional properties of stimulated structure/circuitry contribute to the effect of deep brain stimulation (DBS). We analyzed intracerebral electroencephalographic (EEG) recordings from externalized DBS electrodes targeted bilaterally in the anterior nuclei of the thalamus (ANT) in 12 patients (six responders, six nonresponders) with more than 1 year of follow-up care. In the bipolar local field potentials of the EEG, spectral power (PW) and power spectral entropy (PSE) were calculated in the passbands 1-4, 4-8, 8-12, 12-20, 20-45, 65-80, 80-200 and 200-500 Hz. The most significant differences between responders and nonresponders were observed in the BRIDGE area (bipolar recordings with one contact within the ANT and the second contact in adjacent tissue). In responders, PW was significantly decreased in the frequency bands of 65-80, 80-200, and 200-500 Hz (p < .05); PSE was significantly increased in all frequency bands (p < .05) except for 200-500 Hz (p = .06). The local EEG characteristics of ANT recorded after implantation may play a significant role in DBS response prediction.

Links

GA21-25953S, research and development project

Name: Subkortikální jádra a kortikální funkce z perspektivy hluboké mozkové stimulace (Acronym: DBS3D)

Investor: Czech Science Foundation, Subcortical nuclei and cortical functions – insight from the deep brain stimulation perspective

Citovat

DEUTSCHOVÁ, Barbora, P. KLIMES, Z. JORDAN, P. JURAK, L. EROSS, Martin LAMOŠ, J. HALAMEK, Pavel DANIEL, Ivan REKTOR and D. FABO. Thalamic oscillatory activity may predict response to deep brain stimulation of the anterior nuclei of the thalamus. Epilepsia. Hoboken: Wiley-Blackwell, 2021, vol. 62, No 5, p. "E70"-"E75", 6 pp. ISSN 0013-9580. Available from: https://dx.doi.org/10.1111/epi.16883.

@article{1816727,
   author = {Deutschová, Barbora and Klimes, P. and Jordan, Z. and Jurak, P. and Eross, L. and Lamoš, Martin and Halamek, J. and Daniel, Pavel and Rektor, Ivan and Fabo, D.},
   article_location = {Hoboken},
   article_number = {5},
   doi = {http://dx.doi.org/10.1111/epi.16883},
   keywords = {anterior thalamic nucleus; deep brain stimulation; oscillations; prediction},
   language = {eng},
   issn = {0013-9580},
   journal = {Epilepsia},
   title = {Thalamic oscillatory activity may predict response to deep brain stimulation of the anterior nuclei of the thalamus},
   url = {https://onlinelibrary.wiley.com/doi/10.1111/epi.16883},
   volume = {62},
   year = {2021}
}

TY  - JOUR
ID  - 1816727
AU  - Deutschová, Barbora - Klimes, P. - Jordan, Z. - Jurak, P. - Eross, L. - Lamoš, Martin - Halamek, J. - Daniel, Pavel - Rektor, Ivan - Fabo, D.
PY  - 2021
TI  - Thalamic oscillatory activity may predict response to deep brain stimulation of the anterior nuclei of the thalamus
JF  - Epilepsia
VL  - 62
IS  - 5
SP  - "E70"-"E75"
EP  - "E70"-"E75"
PB  - Wiley-Blackwell
SN  - 00139580
KW  - anterior thalamic nucleus
KW  - deep brain stimulation
KW  - oscillations
KW  - prediction
UR  - https://onlinelibrary.wiley.com/doi/10.1111/epi.16883
N2  - We hypothesized that local/regional properties of stimulated structure/circuitry contribute to the effect of deep brain stimulation (DBS). We analyzed intracerebral electroencephalographic (EEG) recordings from externalized DBS electrodes targeted bilaterally in the anterior nuclei of the thalamus (ANT) in 12 patients (six responders, six nonresponders) with more than 1 year of follow-up care. In the bipolar local field potentials of the EEG, spectral power (PW) and power spectral entropy (PSE) were calculated in the passbands 1-4, 4-8, 8-12, 12-20, 20-45, 65-80, 80-200 and 200-500 Hz. The most significant differences between responders and nonresponders were observed in the BRIDGE area (bipolar recordings with one contact within the ANT and the second contact in adjacent tissue). In responders, PW was significantly decreased in the frequency bands of 65-80, 80-200, and 200-500 Hz (p < .05); PSE was significantly increased in all frequency bands (p < .05) except for 200-500 Hz (p = .06). The local EEG characteristics of ANT recorded after implantation may play a significant role in DBS response prediction.
ER  -

DEUTSCHOVÁ, Barbora, P. KLIMES, Z. JORDAN, P. JURAK, L. EROSS, Martin LAMOŠ, J. HALAMEK, Pavel DANIEL, Ivan REKTOR and D. FABO. Thalamic oscillatory activity may predict response to deep brain stimulation of the anterior nuclei of the thalamus. \textit{Epilepsia}. Hoboken: Wiley-Blackwell, 2021, vol.~62, No~5, p.~''E70''-''E75'', 6 pp. ISSN~0013-9580. Available from: https://dx.doi.org/10.1111/epi.16883.

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