J 2021

Mozart effect in epilepsy: Why is Mozart better than Haydn? Acoustic qualities-based analysis of stereoelectroencephalography

ŠTILLOVÁ, Klára, Tomáš KISKA, Eva KORIŤÁKOVÁ, Ondřej STRÝČEK, J. MEKYSKA et. al.

Basic information

Original name

Mozart effect in epilepsy: Why is Mozart better than Haydn? Acoustic qualities-based analysis of stereoelectroencephalography

Authors

ŠTILLOVÁ, Klára (703 Slovakia, belonging to the institution), Tomáš KISKA (203 Czech Republic, belonging to the institution), Eva KORIŤÁKOVÁ (203 Czech Republic, belonging to the institution), Ondřej STRÝČEK (203 Czech Republic, belonging to the institution), J. MEKYSKA, Jan CHRASTINA (203 Czech Republic, belonging to the institution) and Ivan REKTOR (203 Czech Republic, guarantor, belonging to the institution)

Edition

European Journal of Neurology, Oxford, Rapid Science Ltd. 2021, 1351-5101

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30210 Clinical neurology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 6.288

RIV identification code

RIV/00216224:14740/21:00120200

Organization unit

Central European Institute of Technology

UT WoS

000621067800001

Keywords in English

acoustic characteristics; classical music; epileptiform discharges; Mozart effect

Tags

International impact, Reviewed
Změněno: 5/1/2022 15:23, Mgr. Pavla Foltynová, Ph.D.

Abstract

V originále

Background and purpose We aimed to confirm the Mozart effect in epileptic patients using intracerebral electroencephalography recordings and the hypothesis that the reduction of epileptiform discharges (EDs) can be explained by the music's acoustic properties. Methods Eighteen epilepsy surgery candidates were implanted with depth electrodes in the temporal medial and lateral cortex. Patients listened to the first movement of Mozart's Sonata for Two Pianos K. 448 and to the first movement of Haydn's Symphony No. 94. Musical features from each composition with respect to rhythm, melody, and harmony were analyzed. Results Epileptiform discharges in intracerebral electroencephalography were reduced by Mozart's music. Listening to Haydn's music led to reduced EDs only in women; in men, the EDs increased. The acoustic analysis revealed that nondissonant music with a harmonic spectrum and decreasing tempo with significant high-frequency parts has a reducing effect on EDs in men. To reduce EDs in women, the music should additionally be gradually less dynamic in terms of loudness. Finally, we were able to demonstrate that these acoustic characteristics are more dominant in Mozart's music than in Haydn's music. Conclusions We confirmed the reduction of intracerebral EDs while listening to classical music. An analysis of the musical features revealed that the acoustic characteristics of music are responsible for suppressing brain epileptic activity. Based on our study, we suggest studying the use of musical pieces with well-defined acoustic properties as an alternative noninvasive method to reduce epileptic activity in patients with epilepsy.

Links

NV17-32292A, research and development project
Name: Detekce léze u nelezionální epilepsie s využitím multimodálního zobrazování