The Role of Peridomestic Animals in the Eco-Epidemiology of
Anaplasma phagocytophilum

J 2021

The Role of Peridomestic Animals in the Eco-Epidemiology of Anaplasma phagocytophilum

LESICZKA, Paulina Maria, Kristýna HRAZDILOVÁ, Karolina MAJEROVÁ, Manoj FONVILLE, Hein SPRONG et. al.

Basic information

Original name

The Role of Peridomestic Animals in the Eco-Epidemiology of Anaplasma phagocytophilum

Authors

Edition

Microbial Ecology, New York, Springer, 2021, 0095-3628

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10511 Environmental sciences

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.192

RIV identification code

RIV/00216224:14310/21:00123519

Organization unit

Faculty of Science

DOI

http://dx.doi.org/10.1007/s00248-021-01704-z

UT WoS

000615177000001

Keywords in English

Tick-borne diseases; HGA; Urban wildlife; Hedgehog; Squirrel; Blackbird

Abstract

V originále

Anaplasma phagocytophilum is an important tick-borne zoonotic agent of human granulocytic anaplasmosis (HGA). In Europe, the Ixodes ticks are the main vector responsible for A. phagocytophilum transmission. A wide range of wild animals is involved in the circulation of this pathogen in the environment. Changes in populations of vertebrates living in different ecosystems impact the ecology of ticks and the epidemiology of tick-borne diseases. In this study, we investigated four species, Western European hedgehog (Erinaceus europaeus), northern white-breasted hedgehog (Erinaceus roumanicus), Eurasian red squirrel (Sciurus vulgaris), and the common blackbird (Turdus merula), to describe their role in the circulation of A. phagocytophilum in urban and periurban ecosystems. Ten different tissues were collected from cadavers of the four species, and blood and ear/skin samples from live blackbirds and hedgehogs. Using qPCR, we detected a high rate of A. phagocytophilum: Western European hedgehogs (96.4%), northern white-breasted hedgehogs (92.9%), Eurasian red squirrels (60%), and common blackbirds (33.8%). In the groEL gene, we found nine genotypes belonging to three ecotypes; seven of the genotypes are associated with HGA symptoms. Our findings underline the role of peridomestic animals in the ecology of A. phagocytophilum and indicate that cadavers are an important source of material for monitoring zoonotic pathogens. Concerning the high prevalence rate, all investigated species play an important role in the circulation of A. phagocytophilum in municipal areas; however, hedgehogs present the greatest anaplasmosis risk for humans. Common blackbirds and squirrels carry different A. phagocytophilum variants some of which are responsible for HGA.

Citovat

LESICZKA, Paulina Maria, Kristýna HRAZDILOVÁ, Karolina MAJEROVÁ, Manoj FONVILLE, Hein SPRONG, Václav HÖNIG, Lada HOFMANNOVÁ, Petr PAPEŽÍK, Daniel RŮŽEK, Ludek ZUREK, Jan VOTÝPKA and David MODRÝ. The Role of Peridomestic Animals in the Eco-Epidemiology of Anaplasma phagocytophilum. Microbial Ecology. New York: Springer, 2021, vol. 82, No 3, p. 602-612. ISSN 0095-3628. Available from: https://dx.doi.org/10.1007/s00248-021-01704-z.

@article{1817090,
   author = {Lesiczka, Paulina Maria and Hrazdilová, Kristýna and Majerová, Karolina and Fonville, Manoj and Sprong, Hein and Hönig, Václav and Hofmannová, Lada and Papežík, Petr and Růžek, Daniel and Zurek, Ludek and Votýpka, Jan and Modrý, David},
   article_location = {New York},
   article_number = {3},
   doi = {http://dx.doi.org/10.1007/s00248-021-01704-z},
   keywords = {Tick-borne diseases; HGA; Urban wildlife; Hedgehog; Squirrel; Blackbird},
   language = {eng},
   issn = {0095-3628},
   journal = {Microbial Ecology},
   title = {The Role of Peridomestic Animals in the Eco-Epidemiology of Anaplasma phagocytophilum},
   url = {https://doi.org/10.1007/s00248-021-01704-z},
   volume = {82},
   year = {2021}
}

TY  - JOUR
ID  - 1817090
AU  - Lesiczka, Paulina Maria - Hrazdilová, Kristýna - Majerová, Karolina - Fonville, Manoj - Sprong, Hein - Hönig, Václav - Hofmannová, Lada - Papežík, Petr - Růžek, Daniel - Zurek, Ludek - Votýpka, Jan - Modrý, David
PY  - 2021
TI  - The Role of Peridomestic Animals in the Eco-Epidemiology of Anaplasma phagocytophilum
JF  - Microbial Ecology
VL  - 82
IS  - 3
SP  - 602-612
EP  - 602-612
PB  - Springer
SN  - 00953628
KW  - Tick-borne diseases
KW  - HGA
KW  - Urban wildlife
KW  - Hedgehog
KW  - Squirrel
KW  - Blackbird
UR  - https://doi.org/10.1007/s00248-021-01704-z
N2  - Anaplasma phagocytophilum is an important tick-borne zoonotic agent of human granulocytic anaplasmosis (HGA). In Europe, the Ixodes ticks are the main vector responsible for A. phagocytophilum transmission. A wide range of wild animals is involved in the circulation of this pathogen in the environment. Changes in populations of vertebrates living in different ecosystems impact the ecology of ticks and the epidemiology of tick-borne diseases. In this study, we investigated four species, Western European hedgehog (Erinaceus europaeus), northern white-breasted hedgehog (Erinaceus roumanicus), Eurasian red squirrel (Sciurus vulgaris), and the common blackbird (Turdus merula), to describe their role in the circulation of A. phagocytophilum in urban and periurban ecosystems. Ten different tissues were collected from cadavers of the four species, and blood and ear/skin samples from live blackbirds and hedgehogs. Using qPCR, we detected a high rate of A. phagocytophilum: Western European hedgehogs (96.4%), northern white-breasted hedgehogs (92.9%), Eurasian red squirrels (60%), and common blackbirds (33.8%). In the groEL gene, we found nine genotypes belonging to three ecotypes; seven of the genotypes are associated with HGA symptoms. Our findings underline the role of peridomestic animals in the ecology of A. phagocytophilum and indicate that cadavers are an important source of material for monitoring zoonotic pathogens. Concerning the high prevalence rate, all investigated species play an important role in the circulation of A. phagocytophilum in municipal areas; however, hedgehogs present the greatest anaplasmosis risk for humans. Common blackbirds and squirrels carry different A. phagocytophilum variants some of which are responsible for HGA.
ER  -

LESICZKA, Paulina Maria, Kristýna HRAZDILOVÁ, Karolina MAJEROVÁ, Manoj FONVILLE, Hein SPRONG, Václav HÖNIG, Lada HOFMANNOVÁ, Petr PAPEŽÍK, Daniel RŮŽEK, Ludek ZUREK, Jan VOTÝPKA and David MODRÝ. The Role of Peridomestic Animals in the Eco-Epidemiology of Anaplasma phagocytophilum. \textit{Microbial Ecology}. New York: Springer, 2021, vol.~82, No~3, p.~602-612. ISSN~0095-3628. Available from: https://dx.doi.org/10.1007/s00248-021-01704-z.

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