Detailed Information on Publication Record
2021
Exploring the Emission Pathways in Nitrogen-Doped Graphene Quantum Dots for Bioimaging
GOMEZ PEREZ, Inmaculada Jennifer, Manuel Vasques SULLEIRO, Anna DOLEČKOVÁ, Naděžda PIZÚROVÁ, Jiřina MEDALOVÁ et. al.Basic information
Original name
Exploring the Emission Pathways in Nitrogen-Doped Graphene Quantum Dots for Bioimaging
Authors
GOMEZ PEREZ, Inmaculada Jennifer (724 Spain, belonging to the institution), Manuel Vasques SULLEIRO (724 Spain), Anna DOLEČKOVÁ (203 Czech Republic, belonging to the institution), Naděžda PIZÚROVÁ (203 Czech Republic), Jiřina MEDALOVÁ (203 Czech Republic, belonging to the institution), Rajarshi ROY (356 India, belonging to the institution), David NEČAS (203 Czech Republic) and Lenka ZAJÍČKOVÁ (203 Czech Republic, guarantor, belonging to the institution)
Edition
Journal of Physical Chemistry C, American Chemical Society, 2021, 1932-7447
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
10305 Fluids and plasma physics
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 4.177
RIV identification code
RIV/00216224:14310/21:00119558
Organization unit
Faculty of Science
UT WoS
000704295900032
Keywords in English
Fluorescence; Chemical synthesis; Transmission electron microscopy; Quantum mechanics; Functional groups
Tags
Tags
International impact, Reviewed
Změněno: 15/2/2023 16:48, doc. Mgr. Lenka Zajíčková, Ph.D.
Abstract
V originále
Graphene quantum dots (GQDs) with tunable fluorescence emission promise excellent bioapplication potential, especially in bioimaging. We report the synthesis of nitrogen-doped GQDs (N-GQDs) from glucose and ethylenediamine, cheap and safe chemicals, using a one-step and fast microwave-assisted hydrothermal method. Our N-GQDs exhibit fluorescence in the entire visible spectral region, which extends to near-ultraviolet and slightly to near-infrared. Since the origin of fluorescence and its relation to the structure and synthesis conditions are not yet fully understood, we also concentrated on the fluorescence mechanism explanation. Structural characterization with steady-state and time-resolved photoluminescence measurements indicated that band-to-band transitions, size effect, and different nitrogen and oxygen functional groups play a role in this multicolor emission. Remarkably, we found for the first time the evidence that directly relates a change in the N-GQD work function to the change in oxygen groups under UV irradiation via ultraviolet photoelectron spectroscopy. Thus, we confirmed that for λex ≲ 380 nm, photooxidation processes occurred, which led to chemical modification, thereby lowering the work function in the N-GQDs. The N-GQDs were proved to be highly biocompatible by a cell viability assay using vascular smooth muscle cells. Together with the wide spectral range emission observed in confocal fluorescence imaging, it demonstrated the potential of the N-GQDs for in vitro bioimaging applications.
Links
| EF17_043/0009632, research and development project |
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| EF18_070/0009846, research and development project |
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| EF20_079/0017045, research and development project |
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| GA18-12774S, research and development project |
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| LM2018121, research and development project |
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| LM2018129, research and development project |
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| LQ1601, research and development project |
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| 857560, interní kód MU (CEP code: EF17_043/0009632) |
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