Insights into deja vu: Associations between the frequency of
experience and amplitudes of low-frequency oscillations in
resting-state functional magnetic resonance imaging

J 2022

Insights into deja vu: Associations between the frequency of experience and amplitudes of low-frequency oscillations in resting-state functional magnetic resonance imaging

ZATLOUKALOVÁ, Eva, Michal MIKL, Daniel Joel SHAW, Radek MAREČEK, Lenka SAKÁLOŠOVÁ et. al.

Basic information

Original name

Insights into deja vu: Associations between the frequency of experience and amplitudes of low-frequency oscillations in resting-state functional magnetic resonance imaging

Authors

ZATLOUKALOVÁ, Eva (203 Czech Republic, guarantor, belonging to the institution), Michal MIKL (203 Czech Republic, belonging to the institution), Daniel Joel SHAW (826 United Kingdom of Great Britain and Northern Ireland, belonging to the institution), Radek MAREČEK (203 Czech Republic, belonging to the institution), Lenka SAKÁLOŠOVÁ (703 Slovakia, belonging to the institution), Marie KUŘÁTKOVÁ (203 Czech Republic, belonging to the institution), Kristína MITTEROVÁ (703 Slovakia, belonging to the institution), Barbora SKLENÁROVÁ (703 Slovakia, belonging to the institution) and Milan BRÁZDIL (203 Czech Republic, belonging to the institution)

Edition

European Journal of Neuroscience, Hoboken, WILEY-BLACKWELL, 2022, 0953-816X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30103 Neurosciences

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 3.400

RIV identification code

RIV/00216224:14110/22:00125188

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1111/ejn.15570

UT WoS

000735105600001

Keywords in English

ALFF; default mode network; deja vu; fALFF; resting-state fMRI

Abstract

V originále

The phenomenon of deja vu (DV) has intrigued scientists for decades, yet its neurophysiological underpinnings remain elusive. Brain regions have been identified in which morphometry differs between healthy individuals according to the frequency of their DV experiences. This study built upon these findings by assessing if and how neural activity in these and other brain regions also differ with respect to DV experience. Resting-state fMRI was performed on 68 healthy volunteers, 44 of whom reported DV experiences (DV group) and 24 who did not (NDV group). Using multivariate analyses, we then assessed the (fractional) amplitude of low-frequency fluctuations (fALFF/ALFF), a metric that is believed to index brain tissue excitability, for five discrete frequency bands within sets of brain regions implicated in DV and those comprising the default mode network (DMN). Analyses revealed significantly lower values of fALFF/ALFF for specific frequency bands in the DV relative to the NDV group, particularly within mesiotemporal structures, bilateral putamina, right caudatum, bilateral superior frontal cortices, left lateral parietal cortex, dorsal and ventral medial prefrontal cortex, and the posterior cingulate cortex. The pattern of differences in fALFF/ALFF measures between the brains of individuals who have experienced DV and those who have not provides new neurophysiological insights into this phenomenon, including the potential role of the DMN. We suggest that the erroneous feeling of familiarity arises from a temporary disruption of cortico-subcortical circuitry together with the upregulation of cortical excitability.

Links

EF16_013/0001775, research and development project

Name: Modernizace a podpora výzkumných aktivit národní infrastruktury pro biologické a medicínské zobrazování Czech-BioImaging

90129, large research infrastructures

Name: Czech-BioImaging II

Citovat

ZATLOUKALOVÁ, Eva, Michal MIKL, Daniel Joel SHAW, Radek MAREČEK, Lenka SAKÁLOŠOVÁ, Marie KUŘÁTKOVÁ, Kristína MITTEROVÁ, Barbora SKLENÁROVÁ and Milan BRÁZDIL. Insights into deja vu: Associations between the frequency of experience and amplitudes of low-frequency oscillations in resting-state functional magnetic resonance imaging. European Journal of Neuroscience. Hoboken: WILEY-BLACKWELL, 2022, vol. 55, No 2, p. 426-437. ISSN 0953-816X. Available from: https://dx.doi.org/10.1111/ejn.15570.

@article{1823139,
   author = {Zatloukalová, Eva and Mikl, Michal and Shaw, Daniel Joel and Mareček, Radek and Sakálošová, Lenka and Kuřátková, Marie and Mitterová, Kristína and Sklenárová, Barbora and Brázdil, Milan},
   article_location = {Hoboken},
   article_number = {2},
   doi = {http://dx.doi.org/10.1111/ejn.15570},
   keywords = {ALFF; default mode network; deja vu; fALFF; resting-state fMRI},
   language = {eng},
   issn = {0953-816X},
   journal = {European Journal of Neuroscience},
   title = {Insights into deja vu: Associations between the frequency of experience and amplitudes of low-frequency oscillations in resting-state functional magnetic resonance imaging},
   url = {https://onlinelibrary.wiley.com/doi/10.1111/ejn.15570},
   volume = {55},
   year = {2022}
}

TY  - JOUR
ID  - 1823139
AU  - Zatloukalová, Eva - Mikl, Michal - Shaw, Daniel Joel - Mareček, Radek - Sakálošová, Lenka - Kuřátková, Marie - Mitterová, Kristína - Sklenárová, Barbora - Brázdil, Milan
PY  - 2022
TI  - Insights into deja vu: Associations between the frequency of experience and amplitudes of low-frequency oscillations in resting-state functional magnetic resonance imaging
JF  - European Journal of Neuroscience
VL  - 55
IS  - 2
SP  - 426-437
EP  - 426-437
PB  - WILEY-BLACKWELL
SN  - 0953816X
KW  - ALFF
KW  - default mode network
KW  - deja vu
KW  - fALFF
KW  - resting-state fMRI
UR  - https://onlinelibrary.wiley.com/doi/10.1111/ejn.15570
N2  - The phenomenon of deja vu (DV) has intrigued scientists for decades, yet its neurophysiological underpinnings remain elusive. Brain regions have been identified in which morphometry differs between healthy individuals according to the frequency of their DV experiences. This study built upon these findings by assessing if and how neural activity in these and other brain regions also differ with respect to DV experience. Resting-state fMRI was performed on 68 healthy volunteers, 44 of whom reported DV experiences (DV group) and 24 who did not (NDV group). Using multivariate analyses, we then assessed the (fractional) amplitude of low-frequency fluctuations (fALFF/ALFF), a metric that is believed to index brain tissue excitability, for five discrete frequency bands within sets of brain regions implicated in DV and those comprising the default mode network (DMN). Analyses revealed significantly lower values of fALFF/ALFF for specific frequency bands in the DV relative to the NDV group, particularly within mesiotemporal structures, bilateral putamina, right caudatum, bilateral superior frontal cortices, left lateral parietal cortex, dorsal and ventral medial prefrontal cortex, and the posterior cingulate cortex. The pattern of differences in fALFF/ALFF measures between the brains of individuals who have experienced DV and those who have not provides new neurophysiological insights into this phenomenon, including the potential role of the DMN. We suggest that the erroneous feeling of familiarity arises from a temporary disruption of cortico-subcortical circuitry together with the upregulation of cortical excitability.
ER  -

ZATLOUKALOVÁ, Eva, Michal MIKL, Daniel Joel SHAW, Radek MAREČEK, Lenka SAKÁLOŠOVÁ, Marie KUŘÁTKOVÁ, Kristína MITTEROVÁ, Barbora SKLENÁROVÁ and Milan BRÁZDIL. Insights into deja vu: Associations between the frequency of experience and amplitudes of low-frequency oscillations in resting-state functional magnetic resonance imaging. \textit{European Journal of Neuroscience}. Hoboken: WILEY-BLACKWELL, 2022, vol.~55, No~2, p.~426-437. ISSN~0953-816X. Available from: https://dx.doi.org/10.1111/ejn.15570.

Detailed Information on Publication Record