Biliary obstruction in patients with gallbladder cancer:
national  registry-based analysis

a 2021

Biliary obstruction in patients with gallbladder cancer: national registry-based analysis

ANDRAŠINA, Tomáš, Michal UHER, Matej STRAKA, Peter MATKULČÍK, Tomáš ROHAN et. al.

Basic information

Original name

Biliary obstruction in patients with gallbladder cancer: national registry-based analysis

Authors

ANDRAŠINA, Tomáš (703 Slovakia, guarantor, belonging to the institution), Michal UHER (203 Czech Republic, belonging to the institution), Matej STRAKA (703 Slovakia, belonging to the institution), Peter MATKULČÍK (703 Slovakia, belonging to the institution) and Tomáš ROHAN (203 Czech Republic, belonging to the institution)

Edition

CIRSE 2021, 2021

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30224 Radiology, nuclear medicine and medical imaging

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

RIV identification code

RIV/00216224:14110/21:00120213

Organization unit

Faculty of Medicine

Keywords in English

biliary obstruction; gallbladder cancer; survival analysis

Změněno: 29/1/2022 20:01, MUDr. Tomáš Rohan, Ph.D.

Abstract

V originále

Purpose: To compare efectiveness of plastic and metal stents insertion on survival in patients with gallbladder cancer. Materials and Methods: 3741 patients with diagnosis of gallbladder cancer between 2010-2018 were extracted from the databases of The Czech National Cancer Registry. The analysis was supported by data from the National Registry of Paid Health Services and the Death Records Database. 934 and 201 patients underwent plastic drain insertion and metal stent insertion, respectively. Patients treated with surgical procedure prior or after interventional procedure were analyzed separately. Overall survival after drain/stent insertion and disease diagnosis was assessed. Descriptive statistics and Kaplan-Maier analyses were used. Results: 577 patients with plastic drain insertion and 128 patients with metal stent insertion were enrolled for survival analyses. The survival after plastic drain and metal stent insertion was 2.7 months (95%CI 2.4-3.0) and 3.2 months (95%CI 2.6-3.7), respectively, p>0.05. The patients with inserted plastic drain followed by surgical treatment survived 3.2 - 15.1 months, patients treated only with plastic drain just 1.7 (95%CI 1.5-2.0) months. Insertion of plastic drain after surgery results in survival of 10.1 - 13.1 months. The metal stent insertion in patients without any additional treatment results in survival of 2.4 (95%CI 0.7-4.2) months. Conclusion: According to population-based data, the treatment of biliary obstruction in patients with unresectable gallbladder cancer with metal stent insertion is not accompanied with survival beneft compared to treatment with plastic drain. Data gathering from cancer register databases can provide further information on treatment efectiveness.

Links

MUNI/A/1342/2020, interní kód MU

Name: Význam radiologických intervencí a pokročilých zobrazovacích metod v diagnostice a léčbě onkologických pacientů II

Investor: Masaryk University

NU21-08-00561, research and development project

Name: Využití ireverzibilní elektroporace a vysokofrekvenční ireverzibilní elektroporace k léčbě okluzí metalických stentů

Investor: Ministry of Health of the CR, Subprogram 1 - standard

Citovat

ANDRAŠINA, Tomáš, Michal UHER, Matej STRAKA, Peter MATKULČÍK and Tomáš ROHAN. Biliary obstruction in patients with gallbladder cancer: national registry-based analysis. In CIRSE 2021. 2021.

@proceedings{1823807,
   author = {Andrašina, Tomáš and Uher, Michal and Straka, Matej and Matkulčík, Peter and Rohan, Tomáš},
   booktitle = {CIRSE 2021},
   keywords = {biliary obstruction; gallbladder cancer; survival analysis},
   language = {eng},
   title = {Biliary obstruction in patients with gallbladder cancer: national registry-based analysis},
   url = {https://link.springer.com/content/pdf/10.1007/s00270-021-02939-6.pdf},
   year = {2021}
}

TY  - CONF
ID  - 1823807
AU  - Andrašina, Tomáš - Uher, Michal - Straka, Matej - Matkulčík, Peter - Rohan, Tomáš
PY  - 2021
TI  - Biliary obstruction in patients with gallbladder cancer: national registry-based analysis
KW  - biliary obstruction
KW  - gallbladder cancer
KW  - survival analysis
UR  - https://link.springer.com/content/pdf/10.1007/s00270-021-02939-6.pdf
N2  - Purpose: To compare efectiveness of plastic and metal stents insertion on survival in patients with gallbladder cancer. Materials and Methods: 3741 patients with diagnosis of gallbladder cancer between 2010-2018 were extracted from the databases of The Czech National Cancer Registry. The analysis was supported by data from the National Registry of Paid Health Services and the Death Records Database. 934 and 201 patients underwent plastic drain insertion and metal stent insertion, respectively. Patients treated with surgical procedure prior or after interventional procedure were analyzed separately. Overall survival after drain/stent insertion and disease diagnosis was assessed. Descriptive statistics and Kaplan-Maier analyses were used. Results: 577 patients with plastic drain insertion and 128 patients with metal stent insertion were enrolled for survival analyses. The survival after plastic drain and metal stent insertion was 2.7 months (95%CI 2.4-3.0) and 3.2 months (95%CI 2.6-3.7), respectively, p>0.05. The patients with inserted plastic drain followed by surgical treatment survived 3.2 - 15.1 months, patients treated only with plastic drain just 1.7 (95%CI 1.5-2.0) months. Insertion of plastic drain after surgery results in survival of 10.1 - 13.1 months. The metal stent insertion in patients without any additional treatment results in survival of 2.4 (95%CI 0.7-4.2) months. Conclusion: According to population-based data, the treatment of biliary obstruction in patients with unresectable gallbladder cancer with metal stent insertion is not accompanied with survival beneft compared to treatment with plastic drain. Data gathering from cancer register databases can provide further information on treatment efectiveness.
ER  -

ANDRAŠINA, Tomáš, Michal UHER, Matej STRAKA, Peter MATKULČÍK and Tomáš ROHAN. Biliary obstruction in patients with gallbladder cancer: national registry-based analysis. In \textit{CIRSE 2021}. 2021.

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