Abietane diterpenes of the genus plectranthus sensu lato

J 2022

Abietane diterpenes of the genus plectranthus sensu lato

GÁBOROVÁ, Mária, Karel ŠMEJKAL and Renata KUBÍNOVÁ

Basic information

Original name

Abietane diterpenes of the genus plectranthus sensu lato

Authors

GÁBOROVÁ, Mária (703 Slovakia, guarantor, belonging to the institution), Karel ŠMEJKAL (203 Czech Republic, belonging to the institution) and Renata KUBÍNOVÁ (203 Czech Republic, belonging to the institution)

Edition

Molecules, Basel, MDPI, 2022, 1420-3049

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 4.600

RIV identification code

RIV/00216224:14160/22:00125323

Organization unit

Faculty of Pharmacy

DOI

http://dx.doi.org/10.3390/molecules27010166

UT WoS

000748211400001

Keywords in English

Abietane; Coleon; Diterpene; Hydroquinone; Lanugon; Plectranthus; Royleanone; Spirocoleon

Abstract

V originále

Plectranthus (Lamiaceae), which—according to the latest systematic revision—includes three separate genera (Coleus, Plectranthus sensu stricto, and Equilabium), is a genus widely used in traditional medicine—mainly in the treatment of various ailments of the digestive tract, respiratory tract, and skin. Many species of Plectranthus s.l. have been shown to produce phenolic compounds and terpenes. Diterpenes, especially those of the abietane class, are the most studied group of secondary metabolites found in Plectranthus s.l., which is characterized by a significant structural diversity arising from the oxygenation and further rearrangement of the basic tricyclic abietane skeleton to a complete aromatization of the ring system. This review summarizes the known information on abietane diterpenes, showing their structures, sources, and biosynthesis. A classification of these compounds into nine groups, according to the arrangement of their ring C, is used. Royleanones, spirocoleons, and hydroquinones are the largest classes of abietane diterpenes, covering more than 70% of all the compounds reviewed.

Links

MUNI/A/1688/2020, interní kód MU

Name: Izolace sekundárních metabolitů s potenciální biologickou aktivitou z rostlinných zdrojů (Acronym: Izolace sekundárních metabolitů)

Investor: Masaryk University

Citovat

GÁBOROVÁ, Mária, Karel ŠMEJKAL and Renata KUBÍNOVÁ. Abietane diterpenes of the genus plectranthus sensu lato. Molecules. Basel: MDPI, 2022, vol. 27, No 1, p. 1-64. ISSN 1420-3049. Available from: https://dx.doi.org/10.3390/molecules27010166.

@article{1829958,
   author = {Gáborová, Mária and Šmejkal, Karel and Kubínová, Renata},
   article_location = {Basel},
   article_number = {1},
   doi = {http://dx.doi.org/10.3390/molecules27010166},
   keywords = {Abietane; Coleon; Diterpene; Hydroquinone; Lanugon; Plectranthus; Royleanone; Spirocoleon},
   language = {eng},
   issn = {1420-3049},
   journal = {Molecules},
   title = {Abietane diterpenes of the genus plectranthus sensu lato},
   url = {https://www.mdpi.com/1420-3049/27/1/166},
   volume = {27},
   year = {2022}
}

TY  - JOUR
ID  - 1829958
AU  - Gáborová, Mária - Šmejkal, Karel - Kubínová, Renata
PY  - 2022
TI  - Abietane diterpenes of the genus plectranthus sensu lato
JF  - Molecules
VL  - 27
IS  - 1
SP  - 1-64
EP  - 1-64
PB  - MDPI
SN  - 14203049
KW  - Abietane
KW  - Coleon
KW  - Diterpene
KW  - Hydroquinone
KW  - Lanugon
KW  - Plectranthus
KW  - Royleanone
KW  - Spirocoleon
UR  - https://www.mdpi.com/1420-3049/27/1/166
N2  - Plectranthus (Lamiaceae), which—according to the latest systematic revision—includes three separate genera (Coleus, Plectranthus sensu stricto, and Equilabium), is a genus widely used in traditional medicine—mainly in the treatment of various ailments of the digestive tract, respiratory tract, and skin. Many species of Plectranthus s.l. have been shown to produce phenolic compounds and terpenes. Diterpenes, especially those of the abietane class, are the most studied group of secondary metabolites found in Plectranthus s.l., which is characterized by a significant structural diversity arising from the oxygenation and further rearrangement of the basic tricyclic abietane skeleton to a complete aromatization of the ring system. This review summarizes the known information on abietane diterpenes, showing their structures, sources, and biosynthesis. A classification of these compounds into nine groups, according to the arrangement of their ring C, is used. Royleanones, spirocoleons, and hydroquinones are the largest classes of abietane diterpenes, covering more than 70% of all the compounds reviewed.
ER  -

GÁBOROVÁ, Mária, Karel ŠMEJKAL and Renata KUBÍNOVÁ. Abietane diterpenes of the genus plectranthus sensu lato. \textit{Molecules}. Basel: MDPI, 2022, vol.~27, No~1, p.~1-64. ISSN~1420-3049. Available from: https://dx.doi.org/10.3390/molecules27010166.

Detailed Information on Publication Record