BEDANOVA, Helena, Jiri ONDRASEK, Petr FILIPENSKÝ, Petr NEMEC and Petr DOBŠÁK. Inverted Takotsubo Cardiomyopathy as an Early Complication After Liver Transplantation. American Journal of Case Reports. Melville: INT SCIENTIFIC INFORMATION, INC, 2021, vol. 22, April 2021, p. "e930484-1"-"e930484-4", 4 pp. ISSN 1941-5923. Available from: https://dx.doi.org/10.12659/AJCR.930484.
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Basic information
Original name Inverted Takotsubo Cardiomyopathy as an Early Complication After Liver Transplantation
Authors BEDANOVA, Helena (203 Czech Republic, guarantor), Jiri ONDRASEK (203 Czech Republic), Petr FILIPENSKÝ (203 Czech Republic, belonging to the institution), Petr NEMEC (203 Czech Republic) and Petr DOBŠÁK (203 Czech Republic, belonging to the institution).
Edition American Journal of Case Reports, Melville, INT SCIENTIFIC INFORMATION, INC, 2021, 1941-5923.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30218 General and internal medicine
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
RIV identification code RIV/00216224:14110/21:00124031
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.12659/AJCR.930484
UT WoS 000653065900001
Keywords in English Female; Liver Diseases Alcoholic; Stress Psychological; Takotsubo Cardiomyopathy
Tags 14110118, 14110225, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 2/2/2022 14:07.
Abstract
Objective: Rare disease Background: Takotsubo cardiomyopathy (TTC) is a cardiac syndrome characterized by transient left ventricle (LV) dysfunction, typically showing apical ballooning due to apical akinesis with preserved basal segment contractility. The inverted form is very uncommon and is characterized by basal segment hypokinesis or akinesis and normal LV apical segment contractility. Case Report: We describe the case of a 49-year-old woman who developed inverted TTC after orthotopic liver transplantation. On day 1 (D1), dyspnea and oliguria suddenly appeared. A chest X-ray showed pulmonary edema, and echocardiography showed severe systolic LV dysfunction with an estimated ejection fraction of approximately 25% and akinesis of basal and midventricular LV segments, normal apical segment contractility, and mild mitral regurgitation. Elevated troponin T, creatine kinase-MB, and N-terminal pro B-type natriuretic peptide were found in the blood sample. Suspected inverted takotsubo cardiomyopathy was confirmed by left ventriculography, with normal apical part motion, akinesis in the other LV parts, and negative coronary angiography. The echocardiographic findings returned to normal on D14, and the patient was discharged from the hospital on D19 with normal LV motion and an ejection fraction of 65%. The transplanted liver function was excellent. Conclusions: Organ transplantation is connected with a great emotional stress because the patient's life depends on the death of another person. Therefore, we have to think about the possibility of stress cardiomyopathy even after liver transplantation, because early diagnosis and treatment can be life-saving for the patient. To our knowledge, this is the first described case of inverted takotsubo cardiomyopathy after liver transplantation.
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