J 2021

Inverted Takotsubo Cardiomyopathy as an Early Complication After Liver Transplantation

BEDANOVA, Helena, Jiri ONDRASEK, Petr FILIPENSKÝ, Petr NEMEC, Petr DOBŠÁK et. al.

Basic information

Original name

Inverted Takotsubo Cardiomyopathy as an Early Complication After Liver Transplantation

Authors

BEDANOVA, Helena (203 Czech Republic, guarantor), Jiri ONDRASEK (203 Czech Republic), Petr FILIPENSKÝ (203 Czech Republic, belonging to the institution), Petr NEMEC (203 Czech Republic) and Petr DOBŠÁK (203 Czech Republic, belonging to the institution)

Edition

American Journal of Case Reports, Melville, INT SCIENTIFIC INFORMATION, INC, 2021, 1941-5923

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30218 General and internal medicine

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

RIV identification code

RIV/00216224:14110/21:00124031

Organization unit

Faculty of Medicine

DOI

UT WoS

000653065900001

Keywords in English

Female; Liver Diseases Alcoholic; Stress Psychological; Takotsubo Cardiomyopathy

Tags

Tags

International impact, Reviewed
Změněno: 2/2/2022 14:07, Mgr. Tereza Miškechová

Abstract

V originále

Objective: Rare disease Background: Takotsubo cardiomyopathy (TTC) is a cardiac syndrome characterized by transient left ventricle (LV) dysfunction, typically showing apical ballooning due to apical akinesis with preserved basal segment contractility. The inverted form is very uncommon and is characterized by basal segment hypokinesis or akinesis and normal LV apical segment contractility. Case Report: We describe the case of a 49-year-old woman who developed inverted TTC after orthotopic liver transplantation. On day 1 (D1), dyspnea and oliguria suddenly appeared. A chest X-ray showed pulmonary edema, and echocardiography showed severe systolic LV dysfunction with an estimated ejection fraction of approximately 25% and akinesis of basal and midventricular LV segments, normal apical segment contractility, and mild mitral regurgitation. Elevated troponin T, creatine kinase-MB, and N-terminal pro B-type natriuretic peptide were found in the blood sample. Suspected inverted takotsubo cardiomyopathy was confirmed by left ventriculography, with normal apical part motion, akinesis in the other LV parts, and negative coronary angiography. The echocardiographic findings returned to normal on D14, and the patient was discharged from the hospital on D19 with normal LV motion and an ejection fraction of 65%. The transplanted liver function was excellent. Conclusions: Organ transplantation is connected with a great emotional stress because the patient's life depends on the death of another person. Therefore, we have to think about the possibility of stress cardiomyopathy even after liver transplantation, because early diagnosis and treatment can be life-saving for the patient. To our knowledge, this is the first described case of inverted takotsubo cardiomyopathy after liver transplantation.