HORN, van N., H. KNIEP, G. BROOCKS, L. MEYER, F. FLOTTMANN, M. BECHSTEIN, J. GOTZ, G. THOMALLA, M. BENDSZUS, S. BONEKAMP, JAR. PFAFF, PR. DELLANI, J. FIEHLER and U. HANNING. ASPECTS Interobserver Agreement of 100 Investigators from the TENSION Study. CLINICAL NEURORADIOLOGY. HEIDELBERG: SPRINGER HEIDELBERG, 2021, vol. 31, No 4, p. 1093-1100. ISSN 1869-1439. Available from: https://dx.doi.org/10.1007/s00062-020-00988-x.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name ASPECTS Interobserver Agreement of 100 Investigators from the TENSION Study
Authors HORN, van N. (guarantor), H. KNIEP, G. BROOCKS, L. MEYER, F. FLOTTMANN, M. BECHSTEIN, J. GOTZ, G. THOMALLA, M. BENDSZUS, S. BONEKAMP, JAR. PFAFF, PR. DELLANI, J. FIEHLER and U. HANNING.
Edition CLINICAL NEURORADIOLOGY, HEIDELBERG, SPRINGER HEIDELBERG, 2021, 1869-1439.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30230 Other clinical medicine subjects
Country of publisher Germany
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.156
RIV identification code RIV/00216224:14110/21:00124106
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1007/s00062-020-00988-x
UT WoS 000612304600001
Keywords (in Czech) Acute stroke therapy; Brain; Endovascular treatment; Interrater reliability; Ischemic stroke; Krippendorff's alpha
Keywords in English Acute stroke therapy; Brain; Endovascular treatment; Interrater reliability; Ischemic stroke; Krippendorff's alpha
Tags Excelence Science, INT, RIV, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 3/5/2022 08:46.
Abstract
Purpose Evaluating the extent of cerebral ischemic infarction is essential for treatment decisions and assessment of possible complications in patients with acute ischemic stroke. Patients are often triaged according to image-based early signs of infarction, defined by Alberta Stroke Program Early CT Score (ASPECTS). Our aim was to evaluate interrater reliability in a large group of readers. Methods We retrospectively analyzed 100 investigators who independently evaluated 20 non-contrast computed tomography (NCCT) scans as part of their qualification program for the TENSION study. Test cases were chosen by four neuroradiologists who had previously scored NCCT scans with ASPECTS between 0 and 8 and high interrater agreement. Percent and interrater agreements were calculated for total ASPECTS, as well as for each ASPECTS region. Results Percent agreements for ASPECTS ratings was 28%, with interrater agreement of 0.13 (95% confidence interval, CI 0.09-0.16), at zero tolerance allowance and 66%, with interrater agreement of 0.32 (95% CI: 0.21-0.44), at tolerance allowance set by TENSION inclusion criteria. ASPECTS region with highest level of agreement was the insular cortex (percent agreement = 96%, interrater agreement = 0.96 (95% CI: 0.94-0.97)) and with lowest level of agreement the M3 region (percent agreement = 68%, interrater agreement = 0.39 [95% CI: 0.17-0.61]). Conclusion Interrater agreement reliability for total ASPECTS and study enrollment was relatively low but seems sufficient for practical application. Individual region analysis suggests that some are particularly difficult to evaluate, with varying levels of reliability. Potential impairment of the supraganglionic region must be examined carefully, particularly with respect to the decision whether or not to perform mechanical thrombectomy.
Links
90128, large research infrastructuresName: CZECRIN III
PrintDisplayed: 25/5/2024 20:41