CIMFLOVÁ, Petra, R. MCDONOUGH, M. KAPPELHOF, N. SINGH, N. KASHANI, J. M. OSPEL, A. M. DEMCHUK, B. K. MENON, M. CHEN, N. SAKAI, J. FIEHLER and M. GOYAL. Perceived Limits of Endovascular Treatment for Secondary Medium-Vessel-Occlusion Stroke. American Journal of Neuroradiology. Denville: American Society of Neuroradiology, 2021, vol. 42, No 12, p. 2188-2193. ISSN 0195-6108. Available from: https://dx.doi.org/10.3174/ajnr.A7327.
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Basic information
Original name Perceived Limits of Endovascular Treatment for Secondary Medium-Vessel-Occlusion Stroke
Authors CIMFLOVÁ, Petra (203 Czech Republic, belonging to the institution), R. MCDONOUGH, M. KAPPELHOF, N. SINGH, N. KASHANI, J. M. OSPEL, A. M. DEMCHUK, B. K. MENON, M. CHEN, N. SAKAI, J. FIEHLER and M. GOYAL (guarantor).
Edition American Journal of Neuroradiology, Denville, American Society of Neuroradiology, 2021, 0195-6108.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30224 Radiology, nuclear medicine and medical imaging
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 4.966
RIV identification code RIV/00216224:14110/21:00124155
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.3174/ajnr.A7327
UT WoS 000711963300001
Keywords in English Endovascular Treatment; Secondary Medium-Vessel-Occlusion Stroke
Tags 14110119, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 15/2/2022 10:03.
Abstract
BACKGROUND AND PURPOSE: Thrombus embolization during mechanical thrombectomy occurs in up to 9% of cases, making secondary medium vessel occlusions of particular interest to neurointerventionalists. We sought to gain insight into the current endovascular treatment approaches for secondary medium vessel occlusion stroke in an international case-based survey because there are currently no clear recommendations for endovascular treatment in these patients. MATERIALS AND METHODS: Survey participants were presented with 3 cases involving secondary medium vessel occlusions, each consisting of 3 case vignettes with changes in the patient?s neurologic status (improvement, no change, unable to assess). Multivariable logistic regression analyses clustered by the respondent?s identity were used to assess factors influencing the decision to treat. RESULTS: In total, 366 physicians (56 women, 308 men, 2 undisclosed) from 44 countries provided 3294 responses to 9 scenarios. Most (54.1%, 1782/3294) were in favor of endovascular treatment. Participants were more likely to treat occlusions in the anterior M2/3 (74.3%; risk ratio = 2.62; 95% CI, 2.27?3.03) or A3 (59.7%; risk ratio = 2.11; 95% CI, 1.83?2.42) segment compared with the M3/4 segment (28.3%; reference). Physicians were less likely to pursue endovascular treatment in patients who showed neurologic improvement than in patients with an unchanged neurologic deficit (49.9% versus 57.0% responses in favor of endovascular treatment, respectively; risk ratio = 0.88, 95% CI, 0.83?0.92). Interventionalists and more experienced physicians were more likely to treat secondary medium vessel occlusions. CONCLUSIONS: Physicians? willingness to treat secondary medium vessel occlusions endovascularly is limited and varies per occlusion location and change in neurologic status. More evidence on the safety and efficacy of endovascular treatment for secondary medium vessel occlusion stroke is needed.
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