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@article{1834338, author = {Koukalová, Renata and Vašina, Jiří and Štika, Jiří and Doubek, Michael and Szturz, Petr}, article_location = {Stuttgart}, article_number = {01}, doi = {http://dx.doi.org/10.1055/a-1650-9704}, keywords = {mastocytosis; positron emission tomography; computed tomography; KIT D816V mutation; osteopenia; osteosclerosis}, language = {eng}, issn = {0029-5566}, journal = {Nuklearmedizin-Nuclear Medicine}, title = {Aggressive systemic mastocytosis with diffuse bone marrow (18) F-FDG uptake}, url = {https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1650-9704}, volume = {61}, year = {2022} }
TY - JOUR ID - 1834338 AU - Koukalová, Renata - Vašina, Jiří - Štika, Jiří - Doubek, Michael - Szturz, Petr PY - 2022 TI - Aggressive systemic mastocytosis with diffuse bone marrow (18) F-FDG uptake JF - Nuklearmedizin-Nuclear Medicine VL - 61 IS - 01 SP - 58-61 EP - 58-61 PB - Schattauer GmbH-Verlag Medizin Naturwissenschaften SN - 00295566 KW - mastocytosis KW - positron emission tomography KW - computed tomography KW - KIT D816V mutation KW - osteopenia KW - osteosclerosis UR - https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1650-9704 N2 - Mastocytosis is a clonal hematopoietic disorder characterized by proliferation of abnormal mast cells in various organs including the skin, digestive system, lymph nodes, and bone marrow. We report on a 75-year-old woman presenting with abdominal pain, vomiting, diarrhoea, myalgia, and weight loss. Abdominal CT showed hepatosplenomegaly with heterogeneous splenic parenchyma, lymphadenopathy, and osteopenia with areas of osteosclerosis but no primary tumour. An 18F-FDG PET/CT revealed an overall low metabolic activity of the lesions with a diffuse bone marrow involvement raising suspicion of a haematological neoplasm. Subsequently, bone marrow and peripheral blood examinations confirmed the diagnosis of aggressive systemic mastocytosis. ER -
KOUKALOVÁ, Renata, Jiří VAŠINA, Jiří ŠTIKA, Michael DOUBEK and Petr SZTURZ. Aggressive systemic mastocytosis with diffuse bone marrow (18) F-FDG uptake. \textit{Nuklearmedizin-Nuclear Medicine}. Stuttgart: Schattauer GmbH-Verlag Medizin Naturwissenschaften, 2022, vol.~61, No~01, p.~58-61. ISSN~0029-5566. Available from: https://dx.doi.org/10.1055/a-1650-9704.
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