Aggressive systemic mastocytosis with diffuse bone marrow (18)
F-FDG uptake

J 2022

Aggressive systemic mastocytosis with diffuse bone marrow (18) F-FDG uptake

KOUKALOVÁ, Renata, Jiří VAŠINA, Jiří ŠTIKA, Michael DOUBEK, Petr SZTURZ et. al.

Basic information

Original name

Aggressive systemic mastocytosis with diffuse bone marrow (18) F-FDG uptake

Authors

KOUKALOVÁ, Renata (203 Czech Republic, belonging to the institution), Jiří VAŠINA (203 Czech Republic, belonging to the institution), Jiří ŠTIKA (203 Czech Republic, belonging to the institution), Michael DOUBEK (203 Czech Republic, belonging to the institution) and Petr SZTURZ (203 Czech Republic, guarantor)

Edition

Nuklearmedizin-Nuclear Medicine, Stuttgart, Schattauer GmbH-Verlag Medizin Naturwissenschaften, 2022, 0029-5566

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30224 Radiology, nuclear medicine and medical imaging

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 1.500

RIV identification code

RIV/00216224:14110/22:00125372

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1055/a-1650-9704

UT WoS

000715521100001

Keywords in English

mastocytosis; positron emission tomography; computed tomography; KIT D816V mutation; osteopenia; osteosclerosis

Abstract

V originále

Mastocytosis is a clonal hematopoietic disorder characterized by proliferation of abnormal mast cells in various organs including the skin, digestive system, lymph nodes, and bone marrow. We report on a 75-year-old woman presenting with abdominal pain, vomiting, diarrhoea, myalgia, and weight loss. Abdominal CT showed hepatosplenomegaly with heterogeneous splenic parenchyma, lymphadenopathy, and osteopenia with areas of osteosclerosis but no primary tumour. An 18F-FDG PET/CT revealed an overall low metabolic activity of the lesions with a diffuse bone marrow involvement raising suspicion of a haematological neoplasm. Subsequently, bone marrow and peripheral blood examinations confirmed the diagnosis of aggressive systemic mastocytosis.

Citovat

KOUKALOVÁ, Renata, Jiří VAŠINA, Jiří ŠTIKA, Michael DOUBEK and Petr SZTURZ. Aggressive systemic mastocytosis with diffuse bone marrow (18) F-FDG uptake. Nuklearmedizin-Nuclear Medicine. Stuttgart: Schattauer GmbH-Verlag Medizin Naturwissenschaften, 2022, vol. 61, No 01, p. 58-61. ISSN 0029-5566. Available from: https://dx.doi.org/10.1055/a-1650-9704.

@article{1834338,
   author = {Koukalová, Renata and Vašina, Jiří and Štika, Jiří and Doubek, Michael and Szturz, Petr},
   article_location = {Stuttgart},
   article_number = {01},
   doi = {http://dx.doi.org/10.1055/a-1650-9704},
   keywords = {mastocytosis; positron emission tomography; computed tomography; KIT D816V mutation; osteopenia; osteosclerosis},
   language = {eng},
   issn = {0029-5566},
   journal = {Nuklearmedizin-Nuclear Medicine},
   title = {Aggressive systemic mastocytosis with diffuse bone marrow (18) F-FDG uptake},
   url = {https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1650-9704},
   volume = {61},
   year = {2022}
}

TY  - JOUR
ID  - 1834338
AU  - Koukalová, Renata - Vašina, Jiří - Štika, Jiří - Doubek, Michael - Szturz, Petr
PY  - 2022
TI  - Aggressive systemic mastocytosis with diffuse bone marrow (18) F-FDG uptake
JF  - Nuklearmedizin-Nuclear Medicine
VL  - 61
IS  - 01
SP  - 58-61
EP  - 58-61
PB  - Schattauer GmbH-Verlag Medizin Naturwissenschaften
SN  - 00295566
KW  - mastocytosis
KW  - positron emission tomography
KW  - computed tomography
KW  - KIT D816V mutation
KW  - osteopenia
KW  - osteosclerosis
UR  - https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-1650-9704
N2  - Mastocytosis is a clonal hematopoietic disorder characterized by proliferation of abnormal mast cells in various organs including the skin, digestive system, lymph nodes, and bone marrow. We report on a 75-year-old woman presenting with abdominal pain, vomiting, diarrhoea, myalgia, and weight loss. Abdominal CT showed hepatosplenomegaly with heterogeneous splenic parenchyma, lymphadenopathy, and osteopenia with areas of osteosclerosis but no primary tumour. An 18F-FDG PET/CT revealed an overall low metabolic activity of the lesions with a diffuse bone marrow involvement raising suspicion of a haematological neoplasm. Subsequently, bone marrow and peripheral blood examinations confirmed the diagnosis of aggressive systemic mastocytosis.
ER  -

KOUKALOVÁ, Renata, Jiří VAŠINA, Jiří ŠTIKA, Michael DOUBEK and Petr SZTURZ. Aggressive systemic mastocytosis with diffuse bone marrow (18) F-FDG uptake. \textit{Nuklearmedizin-Nuclear Medicine}. Stuttgart: Schattauer GmbH-Verlag Medizin Naturwissenschaften, 2022, vol.~61, No~01, p.~58-61. ISSN~0029-5566. Available from: https://dx.doi.org/10.1055/a-1650-9704.

Detailed Information on Publication Record