J 2021

Aseptic meningitis during acute hepatitis E - single center experience

MIHALČIN, Matúš, M. TVRDA, Petra VAŠÍČKOVÁ and Petr HUSA

Basic information

Original name

Aseptic meningitis during acute hepatitis E - single center experience

Name in Czech

Aseptická meningitida při akutní hepatitidě E - zkušenosti z jednoho centra

Authors

MIHALČIN, Matúš (703 Slovakia, guarantor, belonging to the institution), M. TVRDA (203 Czech Republic), Petra VAŠÍČKOVÁ (203 Czech Republic) and Petr HUSA (203 Czech Republic, belonging to the institution)

Edition

Ceska a slovenska neurologie a neurochirurgie, Prague, CZECH MEDICAL SOC, 2021, 1210-7859

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30210 Clinical neurology

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 0.411

RIV identification code

RIV/00216224:14110/21:00124167

Organization unit

Faculty of Medicine

UT WoS

000748803200001

Keywords in English

Aseptic meningitis; acute hepatitis E

Tags

Tags

International impact, Reviewed
Změněno: 26/4/2022 10:42, Mgr. Tereza Miškechová

Abstract

V originále

We would like to describe two rare cases of CNS involvement (aseptic meningitis) in immunocompetent patients with acute hepatitis E, treated at the Department of Infectious Diseases, University Hospital Brno, Czech Republic. In the last decade, it has been recognized that hepatitis E virus (HEV) is also endemic in the CR with the incidence of about 2.6/ 100 000 inhabitants. Most cases of hepatitis E in Europe arise from infected animals such as pigs, wild boar, deer and rabbits. Zoonotic HEV genotypes (HEV genotypes 3–8) are mainly food-borne or transmitted by direct contact, but recent data suggest that infection can also be water-borne or iatrogenic through contaminated blood products. Most patients with acute hepatitis E have no symptoms or the symptoms are indistinguishable from other forms of acute viral hepatitis. There have been several extrahepatic manifestations reported with hepatitis E. We present two cases of neurological involvement in patients with acute hepatitis E, hospitalized from 2018–2020.