MIHALČIN, Matúš, M. TVRDA, Petra VAŠÍČKOVÁ and Petr HUSA. Aseptic meningitis during acute hepatitis E - single center experience. Ceska a slovenska neurologie a neurochirurgie. Prague: CZECH MEDICAL SOC, 2021, vol. 84, No 6, p. 572-573. ISSN 1210-7859. Available from: https://dx.doi.org/10.48095/cccsnn2021572.
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Basic information
Original name Aseptic meningitis during acute hepatitis E - single center experience
Name in Czech Aseptická meningitida při akutní hepatitidě E - zkušenosti z jednoho centra
Authors MIHALČIN, Matúš (703 Slovakia, guarantor, belonging to the institution), M. TVRDA (203 Czech Republic), Petra VAŠÍČKOVÁ (203 Czech Republic) and Petr HUSA (203 Czech Republic, belonging to the institution).
Edition Ceska a slovenska neurologie a neurochirurgie, Prague, CZECH MEDICAL SOC, 2021, 1210-7859.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30210 Clinical neurology
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 0.411
RIV identification code RIV/00216224:14110/21:00124167
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.48095/cccsnn2021572
UT WoS 000748803200001
Keywords in English Aseptic meningitis; acute hepatitis E
Tags 14110214, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 26/4/2022 10:42.
Abstract
We would like to describe two rare cases of CNS involvement (aseptic meningitis) in immunocompetent patients with acute hepatitis E, treated at the Department of Infectious Diseases, University Hospital Brno, Czech Republic. In the last decade, it has been recognized that hepatitis E virus (HEV) is also endemic in the CR with the incidence of about 2.6/ 100 000 inhabitants. Most cases of hepatitis E in Europe arise from infected animals such as pigs, wild boar, deer and rabbits. Zoonotic HEV genotypes (HEV genotypes 3–8) are mainly food-borne or transmitted by direct contact, but recent data suggest that infection can also be water-borne or iatrogenic through contaminated blood products. Most patients with acute hepatitis E have no symptoms or the symptoms are indistinguishable from other forms of acute viral hepatitis. There have been several extrahepatic manifestations reported with hepatitis E. We present two cases of neurological involvement in patients with acute hepatitis E, hospitalized from 2018–2020.
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