SIN, Robin and Denisa ŠTRUNCOVÁ. Status epilepticus as a complication after COVID-19 mRNA-1273 vaccine: A case report. World Journal of Clinical Cases. PLEASANTON: BAISHIDENG PUBLISHING GROUP INC, 2021, vol. 9, No 24, p. 7218-7223. ISSN 2307-8960. Available from: https://dx.doi.org/10.12998/wjcc.v9.i24.7218.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Status epilepticus as a complication after COVID-19 mRNA-1273 vaccine: A case report
Authors SIN, Robin (203 Czech Republic) and Denisa ŠTRUNCOVÁ (203 Czech Republic, guarantor, belonging to the institution).
Edition World Journal of Clinical Cases, PLEASANTON, BAISHIDENG PUBLISHING GROUP INC, 2021, 2307-8960.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30218 General and internal medicine
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 1.534
RIV identification code RIV/00216224:14110/21:00124181
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.12998/wjcc.v9.i24.7218
UT WoS 000727979500031
Keywords in English SARS-CoV-2; COVID-19; mRNA vaccine; Complication of vaccination; Status epilepticus; Case report
Tags 14110131, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 3/3/2022 13:21.
Abstract
BACKGROUND We present a rare case of status epilepticus in a 56-year-old man which arose as a complication after vaccination with the coronavirus disease 2019 (COVID-19) mRNA-1273 vaccine. The patient's history included well-compensated secondary epilepsy. The root cause of the situation was a fever which had developed as a side effect of the vaccination. CASE SUMMARY A 56-year-old man received the first dose of mRNA-1273 vaccine against the severe acute respiratory syndrome-coronavirus-2. The vaccine was administered intramuscularly (100 mg, 0.5 mL). The next morning the man was found to be suffering from fever and headaches while at the same time experiencing general weakness. He lost consciousness suddenly and experienced generalized clonic seizures which turned into status epilepticus. When the Emergency Medical Service arrived the patient was unconscious with spontaneous breathing and generalized clonic seizures. It was necessary to administer diazepam repeatedly. It was also necessary to administer high doses of levetiracetam and temporary propofol. The status epilepticus was brought under control approximately 90 min after the patient's transport to the Emergency Department. A follow-up electroencephalogram no longer revealed abnormal indications of epileptic fit. The patient was temporarily hospitalized in the Intensive Care Unit and after seven days care was discharged without any further apparent effects. CONCLUSION There is currently no specific treatment against COVID-19. Therefore, the benefits of COVID-19 vaccine protection outweigh the risks.
PrintDisplayed: 7/8/2024 18:24