Additive prognostic value of high baseline coronary flow
velocity to ejection fraction during resting echocardiography:
3-year prospective study

J 2023

Additive prognostic value of high baseline coronary flow velocity to ejection fraction during resting echocardiography: 3-year prospective study

ZAGATINA, A., O. GUSEVA, E. KALININA, F. RIGO, M. CAPRNDA et. al.

Basic information

Original name

Additive prognostic value of high baseline coronary flow velocity to ejection fraction during resting echocardiography: 3-year prospective study

Authors

ZAGATINA, A., O. GUSEVA, E. KALININA, F. RIGO, M. CAPRNDA, J. MASAN, K. GAZDIKOVA, P. FIRMENT, D. ULLRICH, L. GASPAR, Peter KRUŽLIAK (703 Slovakia, guarantor, belonging to the institution) and D. SHMATOV

Edition

Acta Cardiologica, Leuven, Acta Cardiologica, 2023, 0001-5385

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

United Kingdom of Great Britain and Northern Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 1.600 in 2022

RIV identification code

RIV/00216224:14110/23:00129951

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1080/00015385.2021.2013004

UT WoS

000738401800001

Keywords in English

Coronary artery flow velocity; transthoracic echocardiography; coronary Doppler; coronary stenoses; cardiovascular prognosis

Abstract

V originále

Background There is a lack of information about the prognostic value of high velocity in coronary arteries during echocardiography. The present study was aimed at investigating the three-year prognostic value of coronary velocity assessment in all patients who were referred for echocardiography examination. Methods The prospective study comprises 747 consecutive patients. Death, myocardial infarction (MI), acute coronary syndrome (ACS), and/or revascularisation were defined as major adverse cardiac events (MACE). Routine echocardiography was added with coronary velocity assessment in the left main, anterior descending, or circumflex coronary arteries by the Doppler method. Results During a median follow-up of 36 months, 192 patients experienced MACE. Deaths occurred more frequently in patients with high local velocity in proximal left-sided segments vs. in middle left-sided segments vs. patients without high coronary velocity (9 vs. 3 vs. 1%, p < 0.0001). Death/MI/ACS occurred in 17 vs. 7 vs. 1%, p < 0.0001, respectively. Age (HR 1.04, 95% CI 1.00; 1.06; p < 0.04), a velocity more than 65 cm/s in any proximal segments of the arteries (HR 4.7, 95% CI 1.9; 11.9; p < 0.002), ejection fraction (HR 0.97, 95% CI 0.94; 0.99; p < 0.007) were strong independent prognostic predictors of death/MI/ACS. The maximal velocity of coronary flow velocity had a significant additive prognostic value to ejection fraction. Conclusions The coronary velocity parameters give long-term prognostic information that can be used to identify persons with a high risk of MACE in consecutive non-selected patients.

Citovat

ZAGATINA, A., O. GUSEVA, E. KALININA, F. RIGO, M. CAPRNDA, J. MASAN, K. GAZDIKOVA, P. FIRMENT, D. ULLRICH, L. GASPAR, Peter KRUŽLIAK and D. SHMATOV. Additive prognostic value of high baseline coronary flow velocity to ejection fraction during resting echocardiography: 3-year prospective study. Acta Cardiologica. Leuven: Acta Cardiologica, 2023, vol. 78, No 4, p. 389-399. ISSN 0001-5385. Available from: https://dx.doi.org/10.1080/00015385.2021.2013004.

@article{1834655,
   author = {Zagatina, A. and Guseva, O. and Kalinina, E. and Rigo, F. and Caprnda, M. and Masan, J. and Gazdikova, K. and Firment, P. and Ullrich, D. and Gaspar, L. and Kružliak, Peter and Shmatov, D.},
   article_location = {Leuven},
   article_number = {4},
   doi = {http://dx.doi.org/10.1080/00015385.2021.2013004},
   keywords = {Coronary artery flow velocity; transthoracic echocardiography; coronary Doppler; coronary stenoses; cardiovascular prognosis},
   language = {eng},
   issn = {0001-5385},
   journal = {Acta Cardiologica},
   title = {Additive prognostic value of high baseline coronary flow velocity to ejection fraction during resting echocardiography: 3-year prospective study},
   url = {https://www.tandfonline.com/doi/full/10.1080/00015385.2021.2013004},
   volume = {78},
   year = {2023}
}

TY  - JOUR
ID  - 1834655
AU  - Zagatina, A. - Guseva, O. - Kalinina, E. - Rigo, F. - Caprnda, M. - Masan, J. - Gazdikova, K. - Firment, P. - Ullrich, D. - Gaspar, L. - Kružliak, Peter - Shmatov, D.
PY  - 2023
TI  - Additive prognostic value of high baseline coronary flow velocity to ejection fraction during resting echocardiography: 3-year prospective study
JF  - Acta Cardiologica
VL  - 78
IS  - 4
SP  - 389-399
EP  - 389-399
PB  - Acta Cardiologica
SN  - 00015385
KW  - Coronary artery flow velocity
KW  - transthoracic echocardiography
KW  - coronary Doppler
KW  - coronary stenoses
KW  - cardiovascular prognosis
UR  - https://www.tandfonline.com/doi/full/10.1080/00015385.2021.2013004
N2  - Background There is a lack of information about the prognostic value of high velocity in coronary arteries during echocardiography. The present study was aimed at investigating the three-year prognostic value of coronary velocity assessment in all patients who were referred for echocardiography examination. Methods The prospective study comprises 747 consecutive patients. Death, myocardial infarction (MI), acute coronary syndrome (ACS), and/or revascularisation were defined as major adverse cardiac events (MACE). Routine echocardiography was added with coronary velocity assessment in the left main, anterior descending, or circumflex coronary arteries by the Doppler method. Results During a median follow-up of 36 months, 192 patients experienced MACE. Deaths occurred more frequently in patients with high local velocity in proximal left-sided segments vs. in middle left-sided segments vs. patients without high coronary velocity (9 vs. 3 vs. 1%, p < 0.0001). Death/MI/ACS occurred in 17 vs. 7 vs. 1%, p < 0.0001, respectively. Age (HR 1.04, 95% CI 1.00; 1.06; p < 0.04), a velocity more than 65 cm/s in any proximal segments of the arteries (HR 4.7, 95% CI 1.9; 11.9; p < 0.002), ejection fraction (HR 0.97, 95% CI 0.94; 0.99; p < 0.007) were strong independent prognostic predictors of death/MI/ACS. The maximal velocity of coronary flow velocity had a significant additive prognostic value to ejection fraction. Conclusions The coronary velocity parameters give long-term prognostic information that can be used to identify persons with a high risk of MACE in consecutive non-selected patients.
ER  -

ZAGATINA, A., O. GUSEVA, E. KALININA, F. RIGO, M. CAPRNDA, J. MASAN, K. GAZDIKOVA, P. FIRMENT, D. ULLRICH, L. GASPAR, Peter KRUŽLIAK and D. SHMATOV. Additive prognostic value of high baseline coronary flow velocity to ejection fraction during resting echocardiography: 3-year prospective study. \textit{Acta Cardiologica}. Leuven: Acta Cardiologica, 2023, vol.~78, No~4, p.~389-399. ISSN~0001-5385. Available from: https://dx.doi.org/10.1080/00015385.2021.2013004.

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