ZAGATINA, A., O. GUSEVA, E. KALININA, F. RIGO, M. CAPRNDA, J. MASAN, K. GAZDIKOVA, P. FIRMENT, D. ULLRICH, L. GASPAR, Peter KRUŽLIAK and D. SHMATOV. Additive prognostic value of high baseline coronary flow velocity to ejection fraction during resting echocardiography: 3-year prospective study. Acta Cardiologica. Leuven: Acta Cardiologica, 2023, vol. 78, No 4, p. 389-399. ISSN 0001-5385. Available from: https://dx.doi.org/10.1080/00015385.2021.2013004.
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Basic information
Original name Additive prognostic value of high baseline coronary flow velocity to ejection fraction during resting echocardiography: 3-year prospective study
Authors ZAGATINA, A., O. GUSEVA, E. KALININA, F. RIGO, M. CAPRNDA, J. MASAN, K. GAZDIKOVA, P. FIRMENT, D. ULLRICH, L. GASPAR, Peter KRUŽLIAK (703 Slovakia, guarantor, belonging to the institution) and D. SHMATOV.
Edition Acta Cardiologica, Leuven, Acta Cardiologica, 2023, 0001-5385.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30201 Cardiac and Cardiovascular systems
Country of publisher United Kingdom of Great Britain and Northern Ireland
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 1.600 in 2022
RIV identification code RIV/00216224:14110/23:00129951
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1080/00015385.2021.2013004
UT WoS 000738401800001
Keywords in English Coronary artery flow velocity; transthoracic echocardiography; coronary Doppler; coronary stenoses; cardiovascular prognosis
Tags 14110121, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Tereza Miškechová, učo 341652. Changed: 5/4/2024 07:26.
Abstract
Background There is a lack of information about the prognostic value of high velocity in coronary arteries during echocardiography. The present study was aimed at investigating the three-year prognostic value of coronary velocity assessment in all patients who were referred for echocardiography examination. Methods The prospective study comprises 747 consecutive patients. Death, myocardial infarction (MI), acute coronary syndrome (ACS), and/or revascularisation were defined as major adverse cardiac events (MACE). Routine echocardiography was added with coronary velocity assessment in the left main, anterior descending, or circumflex coronary arteries by the Doppler method. Results During a median follow-up of 36 months, 192 patients experienced MACE. Deaths occurred more frequently in patients with high local velocity in proximal left-sided segments vs. in middle left-sided segments vs. patients without high coronary velocity (9 vs. 3 vs. 1%, p < 0.0001). Death/MI/ACS occurred in 17 vs. 7 vs. 1%, p < 0.0001, respectively. Age (HR 1.04, 95% CI 1.00; 1.06; p < 0.04), a velocity more than 65 cm/s in any proximal segments of the arteries (HR 4.7, 95% CI 1.9; 11.9; p < 0.002), ejection fraction (HR 0.97, 95% CI 0.94; 0.99; p < 0.007) were strong independent prognostic predictors of death/MI/ACS. The maximal velocity of coronary flow velocity had a significant additive prognostic value to ejection fraction. Conclusions The coronary velocity parameters give long-term prognostic information that can be used to identify persons with a high risk of MACE in consecutive non-selected patients.
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