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@article{1836322,
author = {Brázdil, Vojtěch and Kala, Petr and Hudec, Martin and Poloczek, Martin and Kaňovský, Jan and Štípal, Roman and Jerabek, Petr and Boček, Otakar and Pail, Martin and Brázdil, Milan},
article_location = {HEIDELBERG},
article_number = {1},
doi = {http://dx.doi.org/10.1007/s10286-021-00844-z},
keywords = {Takotsubo syndrome; Brain-heart axis; Insular cortex; Amygdala; Brain connectivity},
language = {eng},
issn = {0959-9851},
journal = {Clinical Autonomic Research},
title = {The role of central autonomic nervous system dysfunction in Takotsubo syndrome: a systematic review},
url = {https://link.springer.com/article/10.1007/s10286-021-00844-z},
volume = {32},
year = {2022}
}
TY - JOUR
ID - 1836322
AU - Brázdil, Vojtěch - Kala, Petr - Hudec, Martin - Poloczek, Martin - Kaňovský, Jan - Štípal, Roman - Jerabek, Petr - Boček, Otakar - Pail, Martin - Brázdil, Milan
PY - 2022
TI - The role of central autonomic nervous system dysfunction in Takotsubo syndrome: a systematic review
JF - Clinical Autonomic Research
VL - 32
IS - 1
SP - 9-17
EP - 9-17
PB - Springer GmbH
SN - 09599851
KW - Takotsubo syndrome
KW - Brain-heart axis
KW - Insular cortex
KW - Amygdala
KW - Brain connectivity
UR - https://link.springer.com/article/10.1007/s10286-021-00844-z
N2 - Introduction Takotsubo syndrome (TTS), also known as stress cardiomyopathy or "broken heart" syndrome, is a mysterious condition that often mimics an acute myocardial infarction. Both are characterized by left ventricular systolic dysfunction. However, this dysfunction is reversible in the majority of TTS patients. Purpose Recent studies surprisingly demonstrated that TTS, initially perceived as a benign condition, has a long-term prognosis akin to myocardial infarction. Therefore, the health consequences and societal impact of TTS are not trivial. The pathophysiological mechanisms of TTS are not yet completely understood. In the last decade, attention has been increasingly focused on the putative role of the central nervous system in the pathogenesis of TTS. Conclusion In this review, we aim to summarize the state of the art in the field of the brain-heart axis, regional structural and functional brain abnormalities, and connectivity aberrancies in TTS.
ER -
BRÁZDIL, Vojtěch, Petr KALA, Martin HUDEC, Martin POLOCZEK, Jan KAŇOVSKÝ, Roman ŠTÍPAL, Petr JERABEK, Otakar BOČEK, Martin PAIL and Milan BRÁZDIL. The role of central autonomic nervous system dysfunction in Takotsubo syndrome: a systematic review. \textit{Clinical Autonomic Research}. HEIDELBERG: Springer GmbH, 2022, vol.~32, No~1, p.~9-17. ISSN~0959-9851. Available from: https://dx.doi.org/10.1007/s10286-021-00844-z.
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